- Energy, Environment, Economic Growth
- Multiple Myeloma Research and Treatments
- Sports Performance and Training
- Cardiovascular and exercise physiology
- Urban Transport and Accessibility
- Acute Myeloid Leukemia Research
- Genetics and Physical Performance
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Protein Degradation and Inhibitors
- Sport and Mega-Event Impacts
- Respiratory viral infections research
- Genomics, phytochemicals, and oxidative stress
- Metabolomics and Mass Spectrometry Studies
- Air Quality and Health Impacts
- Environmental Impact and Sustainability
- Hematopoietic Stem Cell Transplantation
- CAR-T cell therapy research
- Adipose Tissue and Metabolism
- Cardiovascular Effects of Exercise
- Innovation Policy and R&D
- Heart Rate Variability and Autonomic Control
- Diverse Aspects of Tourism Research
- Redox biology and oxidative stress
- Platelet Disorders and Treatments
- Immune responses and vaccinations
Second Affiliated Hospital of Xi'an Jiaotong University
2024-2025
Jackson Laboratory
2023-2025
UConn Health
2023-2025
Shanghai University of Medicine and Health Sciences
2020-2024
Northeast Agricultural University
2024
The Wistar Institute
2024
Princeton University
2024
Thomas Jefferson University
2024
Xi'an Jiaotong University
2024
Civil Aviation University of China
2020-2021
Yang, R, Shen, X, Wang, Y, Voisin, S, Cai, G, Fu, Xu, W, Eynon, N, Bishop, DJ, and Yan, X. ACTN3 R577X gene variant is associated with muscle-related phenotypes in elite Chinese sprint/power athletes. J Strength Cond Res 31(4): 1107-1115, 2017-The polymorphism (rs1815739) has been shown to influence athletic performance. The aim of this study was investigate the prevalence track field athletes, explore its effects on athletes' level competition lower-extremity power. We compared genotypes...
Whether government behaviour or enterprise investment promotes regional innovation performance more effectively remains unclear. This study empirically analyses Chinese panel data from 2008 to 2016 and examines the influences of determination high new technology enterprises, R&D investment, institutional environment on performance. The results indicate that enterprises has a limited positive effect performance, whereas mostly significant effect. Furthermore, moderating relationships negative...
The steady and healthy development of the sports industry can promote regional sustainable development. In order to explore coordination situation driving factors between development, this article builds a coupling evaluation index system dynamic factor for Using entropy method, model random effect model, analyzes comprehensive level, relationship in eleven provinces cities eastern China, from 2013 2017. results show that level China is showing growth trend, growing faster than degree among...
Abstract Background High intensity interval training (HIIT) has been reported to exert better effects on cardiovascular fitness in obesity, but little known about the arterial stiffness (AS) female university students with normal weight obesity (NWO). Thus, this study aimed investigate of HIIT body composition, heart rate (HR), blood pressure (BP), lipids metabolism as well novel parameters propensity for AS (arterial velocity pulse index [AVI], volume [API]) NWO. Methods Forty NWO were...
Peroxiredoxin 6 (PRDX6) is one of the family members with only 1-Cys, using glutathione as electron donor to reduce peroxides in cells. PRDX6 has been frequently studied and its expression was associated poor prognosis many tumors. However, multiple myeloma (MM) relevance MM remain unclear. In our study, we found that overexpressed patients. Its high inversely correlated but positively levels β2-microglobulin (B2M), lactate dehydrogenase (LDH), International Staging System (ISS) stage...
Background: Medical resources, especially blood products, were in short supply during the COVID-19. Less intensive therapy with hypomethylating agents/venetoclax (VEN) seems an effective treatment option for patients acute myeloid leukemia (AML). Objectives: To retrospectively analyze efficacy and safety of VEN combined azacitidine (AZA) young adult newly diagnosed (ND) AML. Design: This was a retrospective study. Methods: The clinical data 25 AML treated + AZA regimen from January 2021 to...
The microbiome regulates the respiratory epithelium's immunomodulatory functions. To explore how microbiome's biodiversity affects microbe-epithelial interactions, we screened 58 phylogenetically diverse microbes for their transcriptomic effect on human primary bronchial air–liquid interface (ALI) cell cultures. We found distinct species- and strain-level differences in host innate immunity epithelial barrier response. Strikingly, that interferon, an antiviral response, was one of most...
Chimeric antigen receptor T-cell (CAR-T) therapy targeting B-cell maturation (BCMA) has shown profound efficacy and manageable toxicity in patients with relapsed/refractory multiple myeloma (RRMM). However, determining the best course of treatment for post-CAR-T relapse remains a significant challenge. We conducted retrospective analysis from phase I LEGEND-2 study (NCT03090659) enrolled at Xi'an site, analysing first salvage line outcomes RRMM who progressed after receiving LCAR-B38M CAR-T...
Based on provincial panel data from 2005 to 2016, this paper analyzes evolving temporal–spatial trends, spatial correlation and influencing factors of carbon emissions in China. The results show that there is a great heterogeneity the trends among provinces regions China, with eastern most obvious. At same time, exists significant agglomeration 30 provinces. It found distribution characteristics are affected by various economic social based extended STIRPAT (Stochastic Impacts Regression...
In order to study the present situation regarding SO2 emissions in China, problems are identified and countermeasures suggestions put forward. This paper analyzes spatial correlation, influencing factors regulatory tools of air pollution 30 provinces on Chinese mainland from 2006–2015. The results exploratory data analysis (ESDA) show that have obvious positive correlations, atmospheric China shows overflow effects agglomeration characteristics. On this basis, impact seven socioeconomical...
Alzheimer's disease (AD) is currently one of the main diseases afflicting elderly in world. In recent years, more and studies have shown that brain energy metabolism disorders are key pathogenic factors early pathological features AD. Many risk such as insulin resistance, mitochondrial dysfunction, oxidative stress, Aβ-amyloid plaques, neurofibrillary tangles hyperphosphorylated tau, aging, neuroinflammation involved disorders. this study, 1,379 Web Science publications on mechanisms AD, all...
Based on the panel data of 30 provinces and cities in China from 2008 to 2017, this paper empirically analyzes current situation development China’s sports industry impact concentration green economic growth by using exploratory spatial analysis method (ESDA), static model dynamic model. The empirical results show that southeast coastal has a good foundation for concentration. along Yangtze River Economic Belt is stage rapid development. obvious positive aggregation characteristics,...
Abstract Acute myeloid leukemia (AML) is one of the most prevalent types and challenging to cure for patients. Basic Leucine Zipper ATF‐Like Transcription Factor (BATF) has been reported participate in development progression numerous tumors. However, its role AML largely unknown. In this study, expression prognostic value BATF were examined AML. Our results demonstrated that was upregulated patients, which significantly correlated with poor clinical characteristics survival. Afterward,...
Objectives:The study aims to analyze the status quo of public health emergency measures taken in China dealing with spread new coronavirus pneumonia , and put forward policy suggestions for system construction improvement.Methods: According official data released by National Health Commission, epidemic infected people from 0:00 on January 24, 2020 24:00 February 23, were quantitatively analyzed through statistical analysis.We used EXCEL software draw overall trend chart Statistical Product...
Objective: Metabolites in body fluids, such as lactate, glucose, and creatinine, have been measured by conventional methods to evaluate physical function performance or athletic status. The objectives of the current study were explore novel metabolite biomarkers professional swimmers with different competition levels using nuclear magnetic resonance (NMR) metabolomics, try establish a model identify status predict competitive potential. Methods: Serum samples collected from 103 elite 84...
With the development of information technology, knowledge acquisition is not just limited to traditional classroom. As a rising educational method, "Massive Open Online Courses (MOOCs)" has attracted extensive attention by circles. Taking 445 pieces journal articles about study MOOCs included in China Academic Journal Network Publishing database (CAJD) from 2013 2016 as samples, this adopts bibliometric analysis method and visual network tool CiteSpace carry out in-depth exploration aspects...
Objective: The manuscript aims to explore the relationship between power performance and SNPs of Chinese elite athletes create polygenic models. Methods: One hundred three were divided into group ( n = 60) endurance 43) by their sports event. Best standing long jump (SLJ) vertical (SVJ) collected. Twenty genotyped SNaPshot. Genotype distribution allele frequency compared groups. Additional genotype data 125 used verify screened SNPs. Predictive identifying models established multivariate...
ABSTRACT Background Venous thromboembolic events (VTEs) are the second‐leading cause of death in cancer patients, with an incidence 5%–17% lymphoma particularly higher those non‐Hodgkin (NHL). Existing risk assessment models (RAMs) like Khorana and ThroLy scores have limitations inadequately validated for NHL patients. Coagulation markers such as D‐dimer, thrombin–antithrombin complex (TAT), thrombomodulin (TM) show a potential predictive value cancer‐associated VTE but lack extensive...
Earthworms enrich the soil and protect health of their ecological environment. Previous studies on these invertebrates determined protein content, hormone secretions, medicinal value, habits, but whole genomic sequence remains incomplete. We performed genome sequencing Metaphire vulgaris (Chen, 1930), which belongs to genus family Megascolecidae. The assembly was 729 Mb, with a N50 contig size 4.2 Mb. In total, 559 contigs were anchored 41 chromosomes according results Hi-C (High-throughput...