A5036722067- Viral gastroenteritis research and epidemiology
- Animal Virus Infections Studies
- Animal Disease Management and Epidemiology
- Virus-based gene therapy research
- Vector-Borne Animal Diseases
- Viral Infections and Immunology Research
- Microbial infections and disease research
- Bamboo properties and applications
- Plant and Fungal Interactions Research
- Telomeres, Telomerase, and Senescence
- Mycobacterium research and diagnosis
- Testicular diseases and treatments
- Tissue Engineering and Regenerative Medicine
- Medical Research and Treatments
- Livestock and Poultry Management
- Mechanical Engineering and Vibrations Research
- Sperm and Testicular Function
- Reproductive Biology and Fertility
- Antenna Design and Analysis
- Veterinary Oncology Research
- Full-Duplex Wireless Communications
- Polyomavirus and related diseases
- Infectious Diseases and Mycology
Kagoshima University
2021-2024
Vietnam National University of Agriculture
2017-2022
University of Miyazaki
2015-2021
Houston Methodist
2015
Since late 2013, after an absence of seven years, outbreaks porcine epidemic diarrhea virus (PEDV) infection have reemerged and swept rapidly across Japan, resulting in significant economic losses. In this study, we report the emergence, mixed infection, genetic characterization 15 novel field PEDV variants with large genomic deletions. The sizes deletion varied between 582 nt (194 aa) 648 (216 at positions 28-714 (10-238) on S gene (protein). Among 17 samples isolated from individual pigs,...
African swine fever virus (ASFV) continues to spread globally causing severe economic losses the pig farmers. Vietnam licensed two live attenuated vaccines based on ASFV strains ASFV-G-ΔI177L and ASFV-G-ΔMGF, control ongoing ASF outbreaks. In 2023, newly emerging highly virulent recombinant viruses containing genetic elements from both p72 genotype I II (rASFV I/II) were reported Northern Vietnam. This study evaluated if vaccine able protect pigs against rASFV I/II strain...
: African swine fever virus (ASFV) continues to spread globally, causing severe economic losses pig farmers. Vietnam licensed two live attenuated vaccines based on the ASFV strains ASFV-G-ΔI177L and ASFV-G-ΔMGF control ongoing ASF outbreaks. In 2023, newly emerging highly virulent recombinant viruses (rASFV I/II) containing genetic elements from both p72 genotype I II were reported Northern Vietnam.
Porcine epidemic diarrhoea virus (PEDV) is the aetiologic agent of porcine (PED), a highly contagious enteric disease that threatening swine industry globally. Since PED was first reported in Southern Vietnam 2009, has spread throughout country and caused substantial economic losses. To identify PEDVs responsible for recent outbreaks, full-length spike (S) gene 25 field PEDV strains collected from seven northern provinces sequenced analysed. The sequence analysis revealed S genes Vietnamese...
Since late 2013, porcine epidemic diarrhea virus (PEDV) has reemerged in Japan and caused severe economic losses to the swine industry. Although PEDV vaccines have been used widely, disease swept rapidly across county, is commonly observed PED-vaccinated farms, recurred domestic herds. To better understand PEDVs responsible for reemerging outbreaks Japan, full-length spike (S), membrane (M), nucleocapsid (N) genes of 45 collected during 2013-2016, were sequenced analyzed.Phylogenetic...
Since late 2013, outbreaks of porcine epidemic diarrhea virus (PEDV) have reemerged in Japan. In the present study, we observed a high detection rate PEDV, with 72.5 % (148/204) samples (suckling, weaned, and sows) 88.5 (77/87) farms experiencing acute found to be positive for PEDV by reverse transcription PCR. Sequencing phylogenic analyses partial spike gene ORF3 demonstrated that all prevailing Japanese isolates belonged novel genotypes differed from previously reported strains two...
Porcine epidemic diarrhoea (PED) is an emerging disease in pigs that causes massive economic losses the swine industry, with high mortality suckling piglets. Early identification of PED virus (PEDV)-infected herd through surveillance or monitoring strategies necessary for mass control PED. However, a common working diagnosis system involves identifying PEDV-infected animals individually, which costly and time-consuming approach. Given above information, thrusts this study were to develop...
We previously reported the coinfection of novel porcine epidemic diarrhoea virus (PEDV) variants bearing large deletions in S protein and PEDVs possessing an intact (S-intact PEDV) domestic pigs Japan. The were frequently observed pig farms with persistent or recurrent infection. To elucidate role infections their tropism properties, we genetically characterized immunohistochemically detected collected primary outbreaks two persistently infected farms. Our results revealed PEDV a 214-amino...
Abstract Classical swine fever (CSF) is an endemic disease in southeastern Asia and one of the most important diseases Vietnam. This study was conducted to characterize pathology natural cases CSF northern Vietnam 2018 their genetic prevalence. A total 10 representative pigs were collected from four provinces (Hung Yen, Ha Noi, Quang Ninh Thai Binh) during five outbreaks examined pathologically. The gross histopathological findings showed expressed as acute or subacute chronic form CSF,...
Porcine epidemic diarrhea virus (PEDV) infection is a highly contagious infectious disease causing watery diarrhea, vomiting, dehydration and high mortality rate in newborn piglets. PEDV can cause economic losses pig industry. In Japan, outbreak occurred with from 2013 to 2015. Even though until now, occurs sporadically. For the control monitoring of infection, not only symptomatic pigs, but also asymptomatic pigs should be identified. The objective this study develop optimize novel indirect...
This is a histopathologic and endocrinologic study of 6 calves diagnosed with cryptorchidism. Cases 1–3 were as resembling testicular regression syndrome. In cases 1 2, the extracted tissue was small, firm, gray-white mass, there lack obvious in case 3. Histopathologically, excised fibrotic remnant inflammation, mineralization, hemosiderin-laden macrophages or lipofuscin-laden macrophages, germ cells interstitial endocrine cells. These findings compared 4–6, which hypoplasia due to had small...
ABSTRACT African swine fever is a highly contagious and devastating disease of pigs. Here, we present the draft genome assemblies three Vietnamese s wine virus (ASFV) isolates: rASF1/2-avac02, rASF1/2-avac03, rASF1/2-avac07. All isolates were closely related to Chinese recombinant ASFV strains genotypes I II.
Porcine reproductive and respiratory syndrome (PRRS), which is caused by the porcine virus (PRRSV), has a significant impact on global pork industry. It results in failure sows issues pigs of all ages. Despite availability vaccines, controlling PRRSV remains challenging, partly owing to limitations cell culture systems. Current methods largely rely primary alveolar macrophages (PAMs), must be harvested from piglets have limited proliferative capacity. Although some simian lines support...
An eighteen-year-old female Eurasian otter became emaciated and died. Necropsy examination revealed nose thoracic cutaneous masses, abdominal subcutaneous mass, multiple nodules in the liver lungs. Malignant melanoma was found mass to have metastasized liver, lungs, kidneys, adrenal glands, mammary glands left mandibular lymph node. The neoplastic cells were labeled for vimentin, melanoma, S100. area consisted of spindle shaped epithelial diagnosed as trichoblastoma. Mammary gland adenoma...
Objective: Autologous adult stem cell therapy for cardiovascular disease has shown minimal or no benefit in clinical trials. This may part be explained by aging-related alteration of secretory function and loss replicative capacity autologous preparations. Previously we have that functional human aortic endothelial cells can increased retroviral overexpression telomerase. However, there is a concern immortalization insertional mutagenesis with this approach. More recently, developed methods...
Combined_supplemental_materials-Fuke_et_al for Severe Degenerative Changes in Cryptorchid Testes Japanese Black Cattle by Naoyuki Fuke, Go Kitahara, Soma Ito, Nguyen Van Diep, Angeline Ping Teh, Uda Zahli Izzati, Ohnmar Myint, Takuya Hirai, Shidow Torisu, Yasuyuki Kaneko, Hiroyuki Sato, Yuichi Hidaka, Takeshi Osawa and Ryoji Yamaguchi Veterinary Pathology