A5046814284- Cancer-related molecular mechanisms research
- Lipid metabolism and disorders
- Nitric Oxide and Endothelin Effects
- Bone and Dental Protein Studies
- Medicinal Plant Pharmacodynamics Research
- Cholesterol and Lipid Metabolism
- Cancer-related gene regulation
- Renin-Angiotensin System Studies
- Peroxisome Proliferator-Activated Receptors
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Liver Disease Diagnosis and Treatment
- Hormonal Regulation and Hypertension
- Caveolin-1 and cellular processes
- Inflammatory mediators and NSAID effects
- Eicosanoids and Hypertension Pharmacology
- Cancer, Lipids, and Metabolism
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Milk Quality and Mastitis in Dairy Cows
- Endometriosis Research and Treatment
- Sphingolipid Metabolism and Signaling
- Biological and pharmacological studies of plants
- Cancer Cells and Metastasis
- Reproductive System and Pregnancy
- Chromatography in Natural Products
- Berberine and alkaloids research
Hunan Agricultural University
2012-2022
Capital Medical University
2021
Central South University
2007-2008
Previous investigations have shown molecular cross-talk among activated adenosine monophosphate-activated protein kinase (AMPK), proprotein convertase subtilisin/kexin type 9 (PCSK9), sterol regulatory element-binding proteins (SREBPs), and low-density lipoprotein receptor (LDLR) that it may be an innovative pharmacologic objective for treating obesity. We scrutinized the beneficial effect of naringin, a flavanone-7- O-glycoside, on obesity mechanisms in present study. arbitrarily divided 50...
Impaired endothelial nitric oxide synthase (eNOS)/nitric (NO) pathway induces atherogenesis. The present study examined whether icariin improves the eNOS/NO to prohibit atherogenesis of apolipoprotein E-null (ApoE-/-) mice. In vitro, primary human umbilical vein cells (HUVECs) were randomly divided into 7 groups: control; vehicle; 10; lyphosphatidylcholine (LPC) group; LPC + 1; 3; and 10. vivo, 80 mice separated 4 groups (n = 20): control, ApoE-/-, ApoE-/- 10, 30. had significantly more...
Background and Purpose: Whether imaging parameters would independently predict stroke recurrence in low-risk minor ischemic (MIS) or transient attack (TIA) according to traditional score system (such as ABCD 2 score, which was termed on the basis of initials five factors: age, blood pressure, clinical features, duration, diabetes) remains unclear. We sought evaluate association between 1-year patients with TIA MIS different risk stratum stratified by score. Methods: included (National...
Osteopontin (OPN), also called cytokine Eta-1, is a pro-inflammatory cytokine. Recent studies have shown that aldosterone increases OPN gene expression in endothelial cells. As flavonoid compound, kaempferol has potent anti-inflammatory properties, but whether regulates signaling and aldosterone-induced still unknown. Human umbilical vein cells (HUVECs) were pretreated with (0, 1, 3, or 10 μmol/L) for 1 h prior to exposure (10(-6) mol/L) 24 h. Aldosterone induced generation of reactive...
Recent studies show that nitric oxide/asymmetric dimethylarginine/dimethylarginine dimethylaminohydrolase (NO/ADMA/DDAH) pathway may contribute to the development of sleep disorder. The objective this study was explore inhibitory effect procyanidin B2 from lotus seedpod (LSPC), a naturally occurring catechin compound, on insomnia and mechanisms involved. experiments were performed in brain Sprague-Dawley rat control insomniac rats treated or not with LSPC (15, 30, 45 mg/kg, intragastrically)...
1. The objective of this study was to examine the beneficial effects kaempferol, a naturally occurring polyphenol, on carcase characteristics in broiler chickens and mechanisms involved regulation. 2. Broiler were randomly divided into 7 groups: control, carrier kaempferol (0·3%), (0·6%), hypercholesterolemic (HLD), HLD (0·6%). 3. Seven weeks after treatment, characteristics, lipid levels blood liver, expression hepatic Angiopoietin-like protein 3 (ANGPTL3) mRNA, adipose lipoprotein lipase...
Angiopoietin-like protein 3 (Angptl3) may promote adipose formation. The objective of this study was to investigate the effect kaempferitrin, a 3,7-diglycosyl flavone, on meat quality in broiler chickens and mechanisms involved. One thousand two hundred were offered commercial diet that supplemented with 0.0 (control), 0.1, 0.3, or 0.9% respectively. After 42 days, kaempferitrin (0.3 0.9%) treatment significantly increased lightness colour. Kaempferitrin supplementation decreased breast...