A5025543833- Advanced Radiotherapy Techniques
- Management of metastatic bone disease
- Spine and Intervertebral Disc Pathology
- Advanced X-ray and CT Imaging
- Medical Imaging Techniques and Applications
- Spinal Fractures and Fixation Techniques
- Radiomics and Machine Learning in Medical Imaging
- Brain Metastases and Treatment
- Soft Robotics and Applications
- Radiation Therapy and Dosimetry
- Glioma Diagnosis and Treatment
- Physics of Superconductivity and Magnetism
- Advances in Oncology and Radiotherapy
- Radiation Effects in Electronics
- Radiation Dose and Imaging
- Sarcoma Diagnosis and Treatment
- Magnetic confinement fusion research
- Brain Tumor Detection and Classification
- Medical Imaging and Analysis
- Particle Accelerators and Free-Electron Lasers
- Atomic and Subatomic Physics Research
- Analytical Chemistry and Sensors
- Particle accelerators and beam dynamics
- Vascular Malformations Diagnosis and Treatment
- Head and Neck Cancer Studies
Stanford University
2023-2025
Stanford Medicine
2024-2025
University of North Carolina at Chapel Hill
2020-2024
Georgia Institute of Technology
2016-2020
State Street (United States)
2018
Dosimetric commissioning and quality assurance (QA) for linear accelerators (LINACs) present a significant challenge clinical physicists due to the high measurement workload stringent precision standards. This is exacerbated radiosurgery LINACs because of increased uncertainty more demanding setup accuracy small-field beams. Optimizing physicists' effort during beam measurements while ensuring measured data crucial efficiency patient safety. To develop LINAC model that embeds prior knowledge...
Abstract Background For patients with spine metastases, stereotactic radiosurgery (SRS) provides excellent local control and pain response. Despite increasing use of this treatment modality, there is no consensus on the optimal dose fractionation SRS for efficacy toxicity. We have initiated a single-center phase III randomized trial that compares two regimens similar biological equivalent (BED) to determine isolated effect control. Methods Patients one three cervical, thoracic, or lumbar...
Detection and segmentation of brain metastases (BMs) play a pivotal role in diagnosis, treatment planning, follow-up evaluations for effective BM management. Given the rising prevalence cases its predominantly multiple onsets, automated is becoming necessary stereotactic radiosurgery. It not only alleviates clinician’s manual workload improves clinical workflow efficiency but also ensures safety, ultimately improving patient care. Recent strides machine learning, particularly deep learning...
Purpose In this study, we investigated computationally and experimentally a hexagonal‐pattern array of spatially fractionated proton minibeams produced by p encil b eam s canning (PBS) technique. Spatial fractionation dose delivery with millimeter or submillimeter beam size has proven to be promising approach significantly increase the normal tissue tolerance. Our goals are obtain an optimized minibeam design show that it is feasible implement at existing clinics. Methods An arrangement one...
This study investigates the applicability of 3D dose predictions from a model trained on one modality to cross-modality automated planning workflow. Additionally, we explore impact integrating multi-criteria optimizer adapting different clinical preferences. Using previously created three-stage UNet in-house 2020 AAPM OpenKBP challenge dataset (340 head and neck plans, planned using 9-field static IMRT), retrospectively generated for 20 patients. These were used generate deliverable IMRT,...
Abstract Background: For patients with spine metastases, stereotactic radiosurgery (SRS) provides excellent local control and pain response. Despite increasing use of this treatment modality, there is no consensus on the optimal dose fractionation SRS for efficacy toxicity. We have initiated a phase III randomized trial that compares two regimens similar biological equivalent (BED) to determine isolated effect control. Methods: Patients one three cervical, thoracic, or lumbar metastases...
OBJECTIVE Brain metastases (BMs) secondary to sarcoma are rare, and their incidence ranges from 1% 8% of all bone soft tissue sarcomas. Although stereotactic radiosurgery (SRS) is widely used for BMs, only a few papers have reported on SRS metastasizing the brain. The purpose this study was evaluate safety effectiveness BM. METHODS authors retrospectively reviewed clinical radiological outcomes patients with BM histopathologically confirmed treated SRS, either as primary treatment or...
To determine the possibility of further improving clinical stereotactic body radiotherapy (SBRT) plans using normal tissue complication probability (NTCP) objectives in order to minimize risk for carotid blowout syndrome (CBOS).10 patients with inoperable locally recurrent head and neck cancer, who underwent SBRT CyberKnife were analyzed. For each patient, three treatment examined: (1) cone-based without delineation ipsilateral internal (clinical plan used treat patients); (2)...
With the increase in precision of treatments delivered using radiotherapy machines, there has been a corresponding rise demand for quality assurance tests that can verify accuracy these machines. One common test, star shot analysis, evaluates isocenter stability machine radiosensitive film or electronic portal imaging device (EPID). This work details development an in-house method automatically processing and EPID images to conduct testing. In contrast commercially available software...