Eleanor Brown

ORCID: 0009-0002-7650-7839
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About
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Research Areas
  • Proteins in Food Systems
  • Lung Cancer Treatments and Mutations
  • Lung Cancer Diagnosis and Treatment
  • Legionella and Acanthamoeba research
  • Advanced Radiotherapy Techniques
  • Advances in Oncology and Radiotherapy
  • Colorectal Cancer Surgical Treatments
  • Infant Nutrition and Health
  • Glycosylation and Glycoproteins Research
  • Enzyme Production and Characterization
  • Cancer Immunotherapy and Biomarkers
  • Peroxisome Proliferator-Activated Receptors
  • Spinal Fractures and Fixation Techniques
  • Colorectal Cancer Screening and Detection
  • Enzyme Structure and Function
  • Management of metastatic bone disease
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Economic and Financial Impacts of Cancer
  • Inhalation and Respiratory Drug Delivery
  • Spine and Intervertebral Disc Pathology
  • Lung Cancer Research Studies
  • Bacterial biofilms and quorum sensing
  • Water Treatment and Disinfection
  • Infection Control and Ventilation
  • Medication Adherence and Compliance

Stanford University
2021-2025

Cancer Institute (WIA)
2024-2025

Stanford Cancer Institute
2024

Stanford Medicine
2024

Centers for Disease Control and Prevention
2005-2014

Eastern Regional Research Center
1974-2012

Fishwell Consulting (Australia)
2007

The University of Texas MD Anderson Cancer Center
2005

United States Department of Agriculture
1995-2004

Jefferson Institute
1997

Stereotactic ablative radiotherapy (SABR) is used for treating lung tumors but can cause toxic effects, including life-threatening damage to central structures. Retrospective data suggested that small up 10 cm3 in volume be well controlled with a biologically effective dose less than 100 Gy.

10.1001/jamaoncol.2023.3495 article EN JAMA Oncology 2023-09-14

Legionella pneumophila will infect biofilm-associated protozoa, and in this way might be protected from disinfectants potable water systems. A base biofilm containing Pseudomonas aeruginosa, Klebsiella pneumoniae, Flavobacterium spp. was grown on steel coupons prior to the addition of L. protozoan H. vermiformis. After 7 d, were removed treated with 0.5 mgl(-1) free residual chlorine (FRC) or monochloramine (MCA) for 15, 60, 180 min 24 h. In a second experiment, only organisms present but an...

10.1080/08927010500044286 article EN Biofouling 2005-01-01

Abstract Background For patients with spine metastases, stereotactic radiosurgery (SRS) provides excellent local control and pain response. Despite increasing use of this treatment modality, there is no consensus on the optimal dose fractionation SRS for efficacy toxicity. We have initiated a single-center phase III randomized trial that compares two regimens similar biological equivalent (BED) to determine isolated effect control. Methods Patients one three cervical, thoracic, or lumbar...

10.1186/s12885-025-13655-6 article EN cc-by BMC Cancer 2025-02-21

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSpectroscopic study of bovine lactoferrinEleanor M. Brown and Richard Parry, Jr.Cite this: Biochemistry 1974, 13, 22, 4560–4565Publication Date (Print):October 1, 1974Publication History Published online1 May 2002Published inissue 1 October 1974https://pubs.acs.org/doi/10.1021/bi00719a014https://doi.org/10.1021/bi00719a014research-articleACS PublicationsRequest reuse permissionsArticle Views320Altmetric-Citations24LEARN ABOUT THESE METRICSArticle...

10.1021/bi00719a014 article EN Biochemistry 1974-10-01

N epsilon-[2H6]Isopropyllysyl-beta-lactoglobulin was prepared by reductive alkylation of beta-lactoglobulin with [2H6]acetone and NaBH4 to provide a 2H (NMR) probe for the study lysine involvement in lipid-protein interactions. Amino acid analysis showed 80% protein's 15 residues be labeled. Unmodified were located through peptide maps produced from CNBr, tryptic, chymotryptic digests labeled protein. Lys47 not modified; Lys135,138,141, along an amphipathic helical rod, each partially...

10.1021/bi00415a031 article EN Biochemistry 1988-07-01

SUMMARY We investigated a mixed outbreak of Legionnaires' disease (LD) and Pontiac fever (PF) at military base to identify the outbreak's environmental source as well known legionellosis risk factors. Base workers with possible were interviewed and, if consenting, underwent testing for legionellosis. A retrospective cohort study collected information on occupants buildings closest source. identified 29 confirmed probable LD 38 PF cases. All cases exposed airborne pathogens from cooling...

10.1017/s0950268813003440 article EN Epidemiology and Infection 2014-01-30

10.1007/978-1-4684-0943-7_8 article EN Advances in experimental medicine and biology 1974-01-01

The health care sector is a major contributor of worldwide greenhouse gas (GHG) emissions. Indirect emissions, including those associated with transportation, make up 82% the US sector's environmental footprint. Radiation therapy (RT) treatment regimens present an opportunity for care-based stewardship owing to high incidence cancer diagnosis, significant utilization RT, and myriad days required curative regimens. Because use short-course RT (SCRT) in rectal has demonstrated noninferior...

10.1016/j.adro.2023.101253 article EN cc-by-nc-nd Advances in Radiation Oncology 2023-04-23

Innovative strategies to increase clinical trial accessibility and equity are needed. We conducted a retrospective review of phase II investigator-initiated determine whether the modification design decentralize study treatment can improve among underrepresented groups. Sociodemographic characteristics, including area deprivation indices, as well site travel distance, time, costs were compared between enrolled participants who received chemotherapy locally did not. Participants lived...

10.1093/jncics/pkae050 article EN cc-by JNCI Cancer Spectrum 2024-06-18

3600 Background: Patients (pts) with rectal cancer who achieve a clinical complete response (cCR) after neoadjuvant therapy may be safely observed and spared the long-term sequela of total mesorectal excision (TME). We hypothesized that novel regimen (short-course radiation boost FOLFOXIRI chemotherapy) would higher cCR rates than historical controls. Methods: conducted single-arm, phase II study short-course followed by for pts >T2N0 or low T2N0M0 adenocarcinoma (NCT04380337). Pts...

10.1200/jco.2024.42.16_suppl.3600 article EN Journal of Clinical Oncology 2024-06-01

Abstract The use of enzymes in chemical processing is gaining favour due to the reduction hazardous chemicals and because it considered be environmentally safe. acyl transfer reaction between primary amines glutamine residues proteins catalysed by enzyme transglutaminase. efficiency microbial transglutaminase attach functional catalyse inter‐ intra‐molecular crosslinks was investigated using reduced carboxymethylated κ‐casein, gelatin wool. Model systems used this research gave evidence both...

10.1002/jsfa.1999 article EN Journal of the Science of Food and Agriculture 2004-11-08

10.1016/s0021-9673(01)89486-3 article EN Journal of Chromatography A 1990-07-01

Abstract Background: For patients with spine metastases, stereotactic radiosurgery (SRS) provides excellent local control and pain response. Despite increasing use of this treatment modality, there is no consensus on the optimal dose fractionation SRS for efficacy toxicity. We have initiated a phase III randomized trial that compares two regimens similar biological equivalent (BED) to determine isolated effect control. Methods: Patients one three cervical, thoracic, or lumbar metastases...

10.21203/rs.3.rs-4096254/v1 preprint EN cc-by Research Square (Research Square) 2024-04-01
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