A5033140339- Neural dynamics and brain function
- Face Recognition and Perception
- Visual perception and processing mechanisms
- Neuroscience and Neural Engineering
- Functional Brain Connectivity Studies
- Photoreceptor and optogenetics research
- Medical Imaging and Analysis
- Toxoplasma gondii Research Studies
- Acute Ischemic Stroke Management
- Medical Image Segmentation Techniques
- HIV Research and Treatment
- Fibroblast Growth Factor Research
- Musculoskeletal Disorders and Rehabilitation
- Global Cancer Incidence and Screening
- Cell Image Analysis Techniques
- Face recognition and analysis
- Machine Learning in Bioinformatics
- Artificial Intelligence in Healthcare and Education
- Morphological variations and asymmetry
- Endometrial and Cervical Cancer Treatments
- CCD and CMOS Imaging Sensors
- Memory and Neural Mechanisms
- Machine Learning in Healthcare
- Heart Rate Variability and Autonomic Control
- Aesthetic Perception and Analysis
The University of Texas at Austin
2021-2023
KU Leuven
2017-2022
Indian Institute of Management Visakhapatnam
2022
Science & Technology Park (Czechia)
2013-2015
Bangalore University
2015
Institute of Bioinformatics
2014-2015
Institute of Medical Sciences
2014
Plasma Proteome Database (PPD; http://www.plasmaproteomedatabase.org/) was initially described in the year 2005 as a part of Human Organization's (HUPO's) pilot initiative on Project. Since then, improvements proteomic technologies and increased throughput have led to identification large number novel plasma proteins. To keep up with this increase data, we significantly enriched information PPD. This database currently contains 10 546 proteins detected serum/plasma which 3784 been reported...
Referral workflow inefficiencies, including misaligned referrals and delays, contribute to suboptimal patient outcomes higher healthcare costs. In this study, we investigated the possibility of predicting procedural needs based on primary care diagnostic entries, thereby improving referral accuracy, streamlining workflows, providing better patients. A de-identified dataset 2,086 orthopedic from University Texas Health at Tyler was analyzed using machine learning models built Base General...
Cervical cancer is the third largest cause of mortality in India. The objectives study were to compare pre and post treatment quality life cervical patients develop a prediction model provide an insight into possibilities modules.A total 198 assessed with two structured questionnaires Health Related Quality Life (The European Organisation for Research Treatment Cancer, EORTC QLQ C-30 CX-24). baseline observations recorded when first reported (T1) second evaluation was done at 6 months (T2)....
Although the neural processing of visual images bodies is critical for survival, it much less well understood than face processing. Functional imaging studies demonstrated body selective regions in primate inferior temporal cortex. To advance our understanding how brain represents bodies, we compared representation animate and inanimate objects two such patches with fMRI-guided single unit recordings rhesus monkeys. We found that middle Superior Temporal Sulcus patch (MSB) distinguishes to a...
Lesion studies are crucial in establishing brain-behavior relationships, and accurately segmenting the lesion represents first step achieving this. Manual segmentation is gold standard for chronic strokes. However, it labor-intensive, subject to bias, limits sample size. Therefore, our objective develop an automatic algorithm stroke lesions on T1-weighted MR images. Methods: To train model, we utilized open-source dataset: ATLAS v2.0 (Anatomical Tracings of Lesions After Stroke). We...
Abstract Functional MRI studies in primates have demonstrated cortical regions that are strongly activated by visual images of bodies. The presence such body patches macaques allows characterization the stimulus selectivity their single neurons. Middle superior temporal sulcus (MSB) patch neurons showed similar for natural, shaded, and textured compared with silhouettes, suggesting shape is an important determinant MSB responses. Here, we examined modeled We measured responses to a variety...
Can direct stimulation of primate V1 substitute for a visual stimulus and mimic its perceptual effect? To address this question, we developed an optical-genetic toolkit to ‘read’ neural population responses using widefield calcium imaging, while simultaneously optogenetics ‘write’ into behaving macaques. We focused on the phenomenon masking, where detection dim target is significantly reduced by co-localized medium-brightness mask (Cornsweet Pinsker, 1965; Whittle Swanston, 1974). Using our...
Toxoplasma encephalitis is caused by the opportunistic protozoan parasite gondii. Primary infection with T. gondii in immunocompetent individuals remains largely asymptomatic. In contrast, immunocompromised individuals, reactivation of results severe complications and mortality. Molecular changes at protein level host central nervous system proteins associated pathogenesis toxoplasma are unexplored. We used a global quantitative proteomic strategy to identify differentially regulated...
Brain proteome profile of cryptococcal meningitis co-infected with HIV.
Objective: The objective of this study is to investigate whether preeclampsia associated with exacerbation insulin resistance. Materials and Methods: was conducted over a period 7 months from November 2011 May 2012, in tertiary care hospital attached medical college. A total 14 pregnant women the third trimester were recruited for well-matched normotensive taken as control. 15 g, 50% dextrose load given intravenously blood sampling carried out glucose levels up 3 h afterward. Minimal model...
Functional imaging and electrophysiological studies in primates revealed the existence of patches selective for visual categories inferior temporal cortex. Understanding contribution these to perception requires causal techniques that assess effect neural activity manipulations on perception. We used electrical microstimulation (EM) determine role body patch categorization macaques. tested hypothesis EM a would affect bodies versus objects but not other categories. employed low-current an...
An unresolved question in cognitive neuroscience is how representations of object categories at different levels (basic and superordinate) develop during the course neural response within an area. To address this, we decoded from spiking responses populations neurons recorded two fMRI-defined body patches macaque STS. Recordings were made same animals with stimuli. Support vector machine classifiers trained brief epochs tested or epochs, thus assessing whether category change response. In...
BackgroundThe purpose of this study was to compare the circulatory responses isometric exercise in hypertensive individuals with healthy controls South West Punjab.Aims and objectivesThis carried out examine pressor response hypertensives, it individuals.Materials MethodsThe hand-grip test employed for study.ResultsWe found that hypertensives have a higher vascular reactivity most commonly used anti-hypertensive agents are unable block rise.We conclude should avoid strenuous exercises as...
Abstract Can direct stimulation of primate V1 substitute for a visual stimulus and mimic its perceptual effect? To address this question, we developed an optical-genetic toolkit to “read” neural population responses using widefield calcium imaging, while simultaneously optogenetics “write” into behaving macaques. We focused on the phenomenon masking, where detection dim target is significantly reduced by co-localized medium-brightness pedestal. Using our toolkit, tested whether optogenetic...
Lesion studies are crucial in establishing brain-behavior relationships, and accurately segmenting the lesion represents first step achieving this. Manual segmentation is gold standard for chronic strokes. However, it labor-intensive, subject to bias, limits sample size. Therefore, our objective develop an automatic algorithm stroke lesions on T1-weighted MR images. Methods: To train model, we utilized open-source dataset: ATLAS v2.0 (Anatomical Tracings of Lesions After Stroke). We...
Event Abstract Back to Single unit feature selectivity of the midSTS body patch: adaptive stimulus sampling and modeling. Satwant Kumar1* Rufin Vogels1 1 KU Leuven, Neuroscience, Belgium In monkeys (Macaca mulatta), fMRI defined category-selective regions (“body patches”) are more strongly activated by images bodies compared inanimate objects, however quantitative characteristics patch neurons still remain unclear. Mid-STS respond well silhouettes, suggesting that shape determines response...
Event Abstract Back to Neural coding of viewpoint, posture and identity bodies in the macaque midSTS body patch. Satwant Kumar1* Rufin Vogels1 1 KU Leuven, Belgium FMRI studies primates show body-category selective activations temporal cortex. Single unit patch revealed greater activity images containing compared faces objects. However, these neurons showed a marked image selectivity, responding only some images. The selectivity may reflect encoding identity, viewpoint. Here we examined...
<h3>Objective:</h3> To investigate how cognitive decline affects psychometric representations of global (Mini-Mental State Examination (MMSE) and Clinical Dementia Rating scale (CDR)) domain-specific neuropsychological measures. examine the association between β-amyloid burden using tracer Positron Emission Tomography (PET) imaging. <h3>Background:</h3> One central goals neuroscience is to understand anatomical structure relates function. In dementia, functions are disrupted brain regions...
In response to the pressing need for advanced clinical problem-solving tools in healthcare, we introduce BooksMed, a novel framework based on Large Language Model (LLM). BooksMed uniquely emulates human cognitive processes deliver evidence-based and reliable responses, utilizing GRADE (Grading of Recommendations, Assessment, Development, Evaluations) effectively quantify evidence strength. For decision-making be appropriately assessed, an evaluation metric that is clinically aligned...
We modelled the shape selectivity of single neurons midSTS body patch macaques (Popivanov et al., J. Neurosci., 2014). employed "adaptive stimulus sampling" (Brincat and Connor, Nat. 2004), producing shapes that were adapted on-line to response each neuron during recordings. This procedure resulted in a large number shapes, eliciting wide range responses for neuron. fit quantitative models separately (n = 77). cross-validation fitting procedures model's performance was evaluated with data...