A5021765627- Bone Tissue Engineering Materials
- 3D Printing in Biomedical Research
- Periodontal Regeneration and Treatments
- Orthopaedic implants and arthroplasty
- Dental Implant Techniques and Outcomes
- Graphene and Nanomaterials Applications
- Additive Manufacturing and 3D Printing Technologies
- Facial Trauma and Fracture Management
- Radiomics and Machine Learning in Medical Imaging
- Immunotherapy and Immune Responses
- Anatomy and Medical Technology
- Cavitation Phenomena in Pumps
- Extracellular vesicles in disease
- Ultrasound and Cavitation Phenomena
- Hydraulic flow and structures
- Lung Cancer Research Studies
- Medical Imaging and Analysis
- Fluid Dynamics and Heat Transfer
- Cancer Cells and Metastasis
- Petroleum Processing and Analysis
- Immune cells in cancer
- Cancer Immunotherapy and Biomarkers
- Nanoparticles: synthesis and applications
- Laser Applications in Dentistry and Medicine
- Laser-Ablation Synthesis of Nanoparticles
Wannan Medical College
2017-2025
KU Leuven
2024
Second Affiliated Hospital of Harbin Medical University
2019-2022
Harbin Medical University
2019-2022
University of Hong Kong
2022
University of Hong Kong - Shenzhen Hospital
2022
Harbin University
2020
Beijing Jingshida Electromechanical Equipment Research Institute
2016
Jinzhou Medical University
2015
Tianjin University
2003-2011
The healing of critical-sized bone defects (CSD) remains a challenge in orthopedic medicine. In recent years, scaffolds with sophisticated microstructures fabricated by the emerging three-dimensional (3D) printing technology have lighted up treatment CSD due to elaborate microenvironments and support they may build. Here, we established magnesium oxide-reinforced 3D-printed biocomposite scaffold investigate effect magnesium-enriched 3D microenvironment on repairing. composite was prepared...
Abstract Objective The purpose of this study was to investigate resveratrol's specific role as an anti‐inflammatory and osteogenic differentiation hPDLSCs in periodontitis reveal the mechanisms involved. Background Numerous studies have shown that inhibiting inflammatory response periodontal tissues promoting regeneration alveolar bone are crucial treatments for periodontitis. Resveratrol has been found certain property. However, mechanism effect resveratrol poorly understood. Materials...
Periodontal tissue damage, accompanied by the degradation and destruction of periodontal collagen, is one most clinically common complications difficulty self-repair in patients with diabetes. Human ligament stem cells (PDLSC) are undifferentiated mesenchymal that persist after development ability PDLSC osteogenic differentiation responsible for repairing defects. However, reasons high glucose environment diabetic inhibiting to repair tissues unclear. To address these issues, we propose...
The aim of this study is to explore the therapeutic effects Mg-Sr-Ca containing bioactive glass nanoparticles sodium alginate hydrogel modified mineralized collagen scaffold (Mg-Sr-Ca-BGNs-SA-MC) on repair osteoporotic bone defect. During study, (Mg-Sr-Ca-BGNs) were synthesized using sol-gel method, and Mg-Sr-Ca-BGNs-SA-MC was by a simple method. Mg-Sr-Ca-BGNs observed scanning electron microscopy (SEM) transmission (TEM). elements Mg, Sr, Ca Si effectively integrated into Mg-Sr-Ca-BGNs. SEM...
The aim of this study was to discuss the feasibility porous mineralized collagen plug and bilayer collagen-guided bone regeneration membrane in site preservation extraction sockets. third mandibular premolars on both sides were extracted from four dogs, thus there 16 alveolar sockets all dogs randomly assigned into three groups. Group A had six sockets, groups B C five respectively. Each socket group immediately implanted with a covered after tooth extraction. Alveolar only, set as blank...
To explore the optimal combination of Mg 2+ , Sr and mineralized collagen (nHAC) with two different proportions hydroxyapatite (HA) (COL) on differentiation MC3T3-E1 underlying mechanism, as well achieve bone osseointegration. cells were cultured in a complete medium at concentration 0, 4, 8, 12, 16, 20 mmol/L, 3, 6, 12 impregnation solution 3:7 5:5nHAC. The was measured by expression osteogenic genes proteins including Runx-2, BMP-2 OCN determined activation PI3K/AKT/GSK3β/β-catenin...
This study was aimed at assessing the effects of porous mineralized collagen plug with or without bilayer collagen-guided bone regeneration membrane on alveolar ridge preservation in dogs. The third premolars bilateral maxilla mongrel dogs ( N = 12) were extracted. Twenty-four sockets thus randomly divided into three groups: + (MP, n 8), nonmembrane (NP, 8) and blank group any implantation (BG, 8). Radiographic assessment carried out immediately 2nd, 6th, 12th week after surgery....
Single-factor delivery is the most common characteristic of bone tissue engineering techniques.
Objective: Nonalcoholic fatty liver disease (NAFLD) is a serious threat to human health worldwide. In this study, the aim analyze diagnosis biomarkers in NAFLD and its relationship with immune microenvironment based on bioinformatics analysis. Methods: We downloaded microarray datasets (GSE48452 GSE63067) from Gene Expression Omnibus (GEO) database for screening differentially expressed genes (DEGs). The hub were screened by series of machine learning analyses, such as support vector (SVM),...
Abstract Magnesium containing bioactive glass nanoparticles modified gelatin scaffolds (MBGNs/Gel scaffolds) have shown recently the potential for bone regeneration due to its good biocompatibility, bioresorbability and bioactivity. Nevertheless, use is limited by complicated manufacturing process a relatively expensive price. In this study, MBGNs were prepared sol–gel process. The MBGNs/Gel was synthesized simple immersion method. SEM, transmission electron microscopy dynamic light...
A 3D model coupled with the Volume of Fluid (VOF) method water-air two-phase flow is applied, and roughness walls considered. The simulation covered culvert carried out while Jinan section first-phase in east line south-to-north water diversion project taken as a case. field inverted siphon discussed. inlet outlet transition sections gentle; velocity distribution nonuniform pressure shows layered on current cross section. depth along channel downward.