A5014869520- Orthopaedic implants and arthroplasty
- Manufacturing Process and Optimization
- Microplastics and Plastic Pollution
- Orthopedic Infections and Treatments
- Metallurgy and Material Forming
- Total Knee Arthroplasty Outcomes
- Microstructure and mechanical properties
- Advanced Numerical Analysis Techniques
- Recycling and Waste Management Techniques
- Metal Forming Simulation Techniques
- Magnesium Alloys: Properties and Applications
- Pain Mechanisms and Treatments
- Aluminum Alloys Composites Properties
- Powder Metallurgy Techniques and Materials
- Computational Geometry and Mesh Generation
- Anesthesia and Pain Management
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Adhesion, Friction, and Surface Interactions
- Aluminum Alloy Microstructure Properties
- Nausea and vomiting management
- Pain Management and Opioid Use
- Advanced Multi-Objective Optimization Algorithms
- Land Use and Ecosystem Services
- Neuroinflammation and Neurodegeneration Mechanisms
- Chemokine receptors and signaling
Shanghai Jiao Tong University
2010-2025
Renji Hospital
2018-2025
Central China Normal University
2024
Nankai University
2019-2022
Nanjing Medical University
2022
Wuhan University
2018-2021
Renmin Hospital of Wuhan University
2018-2021
Chinese People's Liberation Army
2018-2021
People's Liberation Army No. 150 Hospital
2021
Chinese PLA General Hospital
2017-2020
Carbon nanotubes are a nanomaterial that is extensively used in industry. The potential health risk of chronic carbon exposure has been raised as great public concern. In the present study, we have demonstrated intratracheal instillation 0.5 mg single-walled (SWCNT) into male ICR mice (8 weeks old) induced alveolar macrophage activation, various inflammatory responses, and severe pulmonary granuloma formation. We then Affymetrix microarrays to investigate molecular effects on macrophages...
Microplastics (MPs) in soils may be ingested by terrestrial animals. While the application of bioplastics is increasing, ingestion and excretion characteristics bio-MPs animals are poorly understood as compared to fossil-MPs. Here, approach–avoidance behavior adult earthworms Eisenia fetida MP-contaminated soil was assessed. Fossil-based poly(ethylene terephthalate) (PET) bio-based poly(lactic acid) (PLA) MPs were found preferred earthworms, which might due odor polymer monomers. earthworm...
A landfill is an important sink of plastic waste and potential sources microplastics (MPs) when mineralized refuse reused. However, limitations are still present in quantifying MPs assessing their degradation degree. In this study, laser direct infrared spectroscopy liquid chromatography-tandem mass spectrometry (LC-MS/MS) were used to identify from a landfill. Although 25–113 items/g detected particles subjected flotation, 37.9–674 μg/g polyethylene terephthalate (PET) 0.0716–1.01...
Polylactic acid (PLA) is the most commonly used biodegradable plastic with rapid growth in recent years. This leads to predictable increased pollution of PLA microplastics (MPs) environment. However, quantification methods for MPs are still lacking. In this study, a method based on alkali-assisted thermal depolymerization and liquid chromatography–tandem mass spectrometry (LC–MS/MS) analysis was developed quantify MPs. After background monomer compound removed, were efficiently depolymerized...
Abstract Sepsis-associated pulmonary fibrosis (SAPF) is a critical pathological stage in the progression of sepsis-induced acute respiratory distress syndrome. While aggregation and activation lung fibroblasts are central to initiation fibrosis, macrophage–myofibroblast transition (MMT) has recently been identified as novel source this context. However, mechanisms driving MMT remain inadequately understood. Given emerging role migrasomes (novel extracellular vesicles mediating intercellular...
Deformation behaviour of AA6061 alloy was investigated using uniaxial compression tests at temperatures from 400 to 500°C and strain rates 0·01 1 s −1 . Stress increases a peak value, then decreases monotonically until reaching steady state. The dependence stress on temperature rate fitted sinh-Arrhenius equation characterised by the Zener–Hollomon parameter with apparent activation energy 208·3 kJ mol Grain orientation spread analysis electron backscattered diffraction indicated dynamic...
Morphine tolerance remains an intractable problem, which hinders its prolonged use in clinical practice. Endoplasmic reticulum (ER) stress has been proved to play a fundamental role the pathogenesis of Alzheimer's disease, diabetes, atherosclerosis, cancer, etc. In this study, we provide first direct evidence that ER may be significant driver morphine tolerance. Binding immunoglobulin protein (BiP), marker, was significantly upregulated neurons spinal dorsal horn rats being treated with for...
Morphine is viewed as one of the classical treatments for intractable pain, but its role limited by side effects, including analgesic tolerance. A few chemokines have been reported to be engaged in mechanisms morphine However, exact roles CXC chemokine 11 (CXCL11) chronic tolerance remain unknown. In this study, Walker 256 mammary gland carcinoma cells were inoculated into tibia rats provoke cancer-induced bone pain. Then, was intrathecally administered twice daily seven consecutive days...
Abstract Background Ultrasound-guided parasternal intercostal nerve block is rarely used for postoperative analgesia, and its value remains unclear. This study aimed to evaluate the effectiveness of ultrasound-guided analgesia in patients undergoing median sternotomy mediastinal mass resection. Methods randomized, double-blind, placebo-controlled trial performed Renmin Hospital, Wuhan University, enrolled 41 participants aged 18–65 years. The scheduled resection by were randomly assigned...
BACKGROUND The aim of this study was to investigate the success rate fungal peri-prosthetic joint infection treated by 2-stage revision and related factors treatment failure offer a better protocol. MATERIAL AND METHODS We reviewed 18 joints (13 knees 5 hips) 17 patients (10 women 7 men) diagnosed with from January 2000 June 2015 at our institute. mean follow-up 65.1 months (range, 25-129 months). All were complete debridement, implantation antifungal-loaded cement spacers, least 6 weeks...
To overcome the limitation in formability at room temperature, manufacturers have developed magnesium alloys with remarkable properties by adding rare-earth elements. The behave differently from conventional alloys, especially respect to their coupled anisotropic and strain rate sensitive behavior. In current work, such behavior of Mg alloy ZEK100 sheet temperature is investigated aid elastic viscoplastic self-consistent polycrystal plasticity model. Different sensitivities (SRSs) for...
BackgroundFibrosis is a heavy burden on the global healthcare system. Recently, an increasing number of studies have demonstrated that Extracellular vesicles play important role in intercellular communication under both physiological and pathological conditions. This study aimed to explore extracellular vesicles' fibrosis using bibliometric methods.MethodsOriginal articles reviews related were obtained from Web Science Core Collection database November 9, 2022. VOSviewer was used obtain...
The elderly population is increasing rapidly worldwide, and frailty a common geriatric syndrome. Comprehensive dietary management strategies may have beneficial effects on prevention reversal. This 3-month single-blind, paralleled, randomized controlled trial compared the of micronutrients and/or protein supplements, personalised diet status in individuals.Between 2014 2015, 40 prefrail or frail subjects aged >=65 years were recruited at Miaoli General Hospital, Taiwan. Of these, 37...
Along with the rapid development of urbanization and industrialization, carrying capacity territorial space has been confronted a serious crisis. Faced many uncertain risks unknown disruptions, it is important to proactively address uncertainty future developments in planning improve spatial resilience (TSR). Based on connotation TSR, we build an assessment framework for TSR containing urban, agricultural ecological from three dimensions, including element, structure function. Using variety...