- Tendon Structure and Treatment
- Antibiotic Use and Resistance
- Pneumonia and Respiratory Infections
- COVID-19 Clinical Research Studies
- Chronic Disease Management Strategies
- Patient Satisfaction in Healthcare
- Bacterial Infections and Vaccines
- Orthopedic Surgery and Rehabilitation
- Sports injuries and prevention
- Bacterial Identification and Susceptibility Testing
- Diabetes Treatment and Management
- Antimicrobial Resistance in Staphylococcus
- Health disparities and outcomes
- Bone fractures and treatments
- Hip and Femur Fractures
- SARS-CoV-2 and COVID-19 Research
- Orthopaedic implants and arthroplasty
- Health, psychology, and well-being
- Urinary Tract Infections Management
- Healthcare Systems and Technology
- Diabetes Management and Education
- Meta-analysis and systematic reviews
- Tracheal and airway disorders
- Acute Myeloid Leukemia Research
- Blood disorders and treatments
Hvidovre Hospital
2019-2024
Amager Hospital
2019-2022
Copenhagen University Hospital
2018-2022
University of Copenhagen
2016-2020
Incretin-based therapies, glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and dipeptidyl peptidase-4 inhibitors (DPP-4i), have been hypothesized to exert beneficial effects on COVID-19 outcomes due anti-inflammatory properties. In this population-based cohort study, we retrieved data from nationwide registries all individuals diagnosed with severe acute respiratory syndrome coronavirus 2 infection up 1 November 2020. For diabetes, examined the impact of use GLP-1 RAs (n = 370) DPP-4i...
The course of COVID-19 is unpredictable, ranging from asymptomatic to respiratory failure and death. Prognostic biomarkers are urgently needed. We hypothesized that long pentraxin PTX3 could be a valuable plasma biomarker due its essential role in inflammatory processes. In prospective hospitalized derivation cohort (<i>n</i> = 126) during the spring 2020, we measured within 4 days admission. predictive value mechanical ventilation (MV) 30-day mortality compared with clinical...
Objective: We investigated the association between socioeconomic factors and attainment of treatment goals pharmacotherapy in patients with type 2 diabetes Denmark.Design: A cross-sectional population study.Setting: The municipality Naestved, Denmark.Subjects: studied 907 identified from a random sample 21,205 Danish citizens.Main outcome measures: proportion who were not achieving for care based on their HbA1c, LDL-cholesterol, blood pressure, lifestyle, treated antihypertensive...
In Denmark, general practice is responsible for 75% of antibiotic prescribing in the primary care sector. We aimed to identify practice-related factors associated with high prescribers, including prescribers critically important antibiotics as defined by WHO, after accounting case mix practice.We performed a nationwide register-based survey Danish from 2012 2013. The unit analysis was individual practice. used multivariable regression analyses and an assessment relative importance driving...
Background: The purpose of this study was to estimate the incidence reoperation and effect implant position on risk within 12 months following osteosynthesis with use parallel implants for femoral neck fractures. Methods: From cases registered in Danish Fracture Database, 1,206 consecutive surgeries a primary fracture treated during period December 2011 November 2015, having available radiographs follow-up data, were reviewed. Data included age, sex, time surgery, classification, American...
Social relationships are important to people and affect their quality of life, morbidity mortality. The aim this study was examine the correlation between elderly patients' descriptions social relations feelings loneliness, general practitioners' assessments these. Cross-sectional in 12 practices Capital Region Denmark. During a three-week period each practice asked patients aged 65 older fill out questionnaire regarding health, loneliness; practitioner (GP) filled matching perception...
Background and purpose - Most guidelines use patient age as a primary decision factor when choosing between osteosynthesis or arthroplasty in displaced femoral neck fractures. We evaluate reoperation death risk within 1 year after osteosynthesis, estimate the influence of age, sex, degree displacement, bone quality.Patients methods All surgeries for fractures with parallel implants (2 3 screws pins) performed December 2011 November 2015 were collected from Danish Fracture Database....
ObjectivesTo describe and compare antibiotic prescribing patterns for primary care patients with respiratory tract infections (RTIs) in four South American countries.
Exposures to human immunodeficiency (HIV) and antiretroviral therapy in utero may have adverse effects on infant growth. Among children born Denmark aged 0-5 years, we aimed compare anthropometric outcomes HIV-exposed but uninfected (HEU) with those not exposed HIV.In a nationwide register-based study included all singleton HEU 2000-2016. were individually matched by child sex, parity, maternal place of birth 5 controls mothers without HIV. Weight-for-age z (WAZ) scores, length-for-age (LAZ)...
Abstract Passive immunotherapy with convalescent plasma may be the only available agent during early phases of a pandemic. Here, we report safety and efficacy high-titer for COVID-19 pneumonia. Double-blinded randomized multicenter placebo-controlled trial adult patients hospitalized The intervention was placebo saline allocated 2:1. primary outcome clinical status 14 days after evaluated on ordinal scale. registered at ClinicalTrials.Gov, NCT04345289, 14/04/2020. CCAP-2 terminated...
Inappropriate prescription of antibiotics is the leading driver antimicrobial resistance (AMR). The majority are prescribed in primary care. Understanding how general practitioners (GPs) use diagnostic tests and effect on treatment decision under daily practice conditions important to reduce inappropriate antibiotics. aim study was investigate care patients with suspected urinary tract infection (UTI) assess appropriateness (TD) Denmark. Prospective observational study. Symptomatic adult...
Abstract Background The recommended duration of antimicrobial treatment for Staphylococcus aureus bacteremia (SAB) is a minimum 14 days. We compared the clinical outcomes patients receiving short-course (SC; 6–10 days), or prolonged-course (PC; 11–16 days) antibiotic therapy low-risk methicillin-susceptible SAB (MS-SAB). Methods Adults with MS-SAB in 1995–2018 were included from 3 independent retrospective cohorts. Logistic regression models fitted inverse probability weighting used to...
The aims of this study were to (1) quantify the development and composition multimorbidity (MM) during 16 years following diagnosis type 2 diabetes (2) evaluate whether effectiveness structured personal care differed between patients with without MM.One thousand three hundred eighty-one newly diagnosed randomized receive either or routine care. Patients followed up for 19 in Danish nationwide registries occurrence outcomes. We analyzed prevalence degree MM based on 10 well-defined disease...
Abstract Background Risk of invasive meningococcal disease (IMD) is increased in patients with complement deficiency and human immunodeficiency virus (HIV) infection. associated comorbidity not well described. Methods This was a nationwide adult case-control study. Cases for the period 1977–2018 were identified by national meningococcus reference laboratory. Matched controls registry linkage. Comorbidities diagnosed prior to IMD based on International Classification Diseases, Eighth or Tenth...
To determine the overall publication rates for abstracts presented at two consecutive Nordic Congresses of General Practice and to evaluate determinants these rates.Prospective study.MEDLINE (PubMed) Google Scholar were searched relevant publications from 1 January 2009 up until 31 August 2014.Abstracts accepted oral or poster presentation identified original congress booklets in 2011. Based on PubMed searches, we subsequently full journal within a 36-month follow-up both congresses. In...