- Spinal Fractures and Fixation Techniques
- Traumatic Brain Injury and Neurovascular Disturbances
- Spine and Intervertebral Disc Pathology
- Cervical and Thoracic Myelopathy
- Trauma and Emergency Care Studies
- Meningioma and schwannoma management
- Traumatic Brain Injury Research
- Neurosurgical Procedures and Complications
- Intracerebral and Subarachnoid Hemorrhage Research
- Dysphagia Assessment and Management
- Nerve Injury and Rehabilitation
- Cardiac, Anesthesia and Surgical Outcomes
- Venous Thromboembolism Diagnosis and Management
- Shoulder and Clavicle Injuries
- Radiation Dose and Imaging
- Hip and Femur Fractures
- Abdominal Trauma and Injuries
- Cerebrospinal fluid and hydrocephalus
- Cardiac Arrest and Resuscitation
- Spinal Cord Injury Research
- Pelvic and Acetabular Injuries
- Cerebral Venous Sinus Thrombosis
- Spinal Dysraphism and Malformations
- Esophageal and GI Pathology
- Neurofibromatosis and Schwannoma Cases
Karolinska Institutet
2021-2025
Stockholm South General Hospital
2023-2024
Karolinska University Hospital
2020-2022
Creative Commons
2020-2021
Witten/Herdecke University
2021
Abstract Purpose This study aimed to investigate whether incorporating pre-injury health status, measured by the American Society of Anesthesiologists (ASA) score, improves outcome prediction models for moderate-to-severe traumatic brain injury (msTBI) patients. Methods We conducted a retrospective single-center msTBI patients (2005–2021). The primary was 1-year Glasgow Outcome Scale (GOS, dichotomized as GOS1-3 (unfavorable) vs. 4–5 (favorable)), and secondary 90-day mortality. Logistic...
Spinal meningiomas are the most common adult primary spinal tumor, constituting 24–45% of intradural tumors and 2% all meningiomas. The aim this study was to assess postoperative complications, long-term outcomes, predictors functional improvement differences between elderly (≥70 years) non-elderly (18–69 patients surgically treated for Variables were retrospectively collected from patient charts magnetic resonance images. Baseline comparisons, paired testing regression analyses used. In...
Abstract Introduction Traumatic subaxial fractures account for more than half of all cervical spine injuries. The optimal surgical approach is a matter debate and may include anterior, posterior or combined anteroposterior (360º) approach. Analyzing cohort patients initially treated with anterior discectomy fusion (ACDF) traumatic injuries, the study aimed to identify predictors treatment failure subsequent need supplementary (PF). Methods A retrospective, single center, consecutive adult...
Preventing intracranial hematoma expansion has been advertised as a possible treatment opportunity in traumatic brain injury (TBI). However, the time course of expansion, and whether affects outcome, remains poorly understood. In light this, aim this study was to use 3D volume rendering determine how hematomas expand over evaluate its impact on outcome.Single-center, population-based, observational cohort adults with moderate-to-severe TBI. Hematoma defined change from baseline computed...
Abstract Purpose The purpose of this study was to evaluate patient-reported outcome measures (PROMS) on dysphagia, health-related quality life (HRQoL) and return work after occipitocervical fixation (OCF). Postoperative radiographic measurements were evaluated identify possible predictors dysphagia. Methods All individuals (≥ 18 years) who underwent an OCF at the center or registered in Swedish spine registry (Swespine) between 2005 2019, still alive when conducted, eligible for inclusion....
Abstract Background Moderate-to-severe traumatic brain injury (TBI) has a global mortality rate of about 30%, resulting in acquired life-long disabilities many survivors. To potentially improve outcomes this TBI population, the management secondary injuries, particularly failure cerebrovascular reactivity (assessed via pressure index; PRx, correlation between intracranial (ICP) and mean arterial blood (MAP)), gained interest field. However, derivation PRx requires high-resolution data...
Abstract Background The first line of treatment for most cervical intradural tumors is surgical resection through laminotomy or laminectomy. This may cause a loss posterior pulling force leading to kyphosis, which associated with decreased functional outcome. However, the incidence and predictors kyphosis in these patients are poorly understood. Object To assess fixation (PF), as well radiological following adults. Methods A population-based cohort study was conducted on adult who underwent...
Spinal meningiomas are the most common primary spinal intradural tumor. This study aimed to assess Health-related quality of life (HRQoL) and frequency return work in patients surgically treated for meningiomas, comparison general population. Variables were collected from patient charts, EQ-5D-3L, specific questionnaires. Patients who had been operated between 2005-2017 identified a previous those alive 2020 (104 129) asked participate. Eighty-four (80.8%) with mean follow-up 8.7 years,...
Contusion expansion (CE) is a potentially treatable outcome predictor in traumatic brain injury (TBI), and suitable end-point for hemostatic therapy trials. However, there no consensus on the definition of clinically relevant CE, both terms measurement criteria (absolute vs. relative volume increase) cutoff values. In light this, aim this study was to assess predictive abilities different CE definitions outcome. We performed multi-center observational cohort adults with moderate-to-severe...
Graphical Abstract Export BACKGROUND Anterior cervical corpectomy and fusion (ACCF) is a treatment option for several pathologies. Various graft materials such as autografts, titanium mesh cages (TMC), or poly-ether-ether-ketone (PEEK) are used. Additional posterior fixation (PF) to provide extra support improve stability sometimes performed initially, later supplementary treatment. OBJECTIVE To describe our retrospective study of 119 consecutive cases ACCF with synthetic grafts, in 3...
Retrospective population-based cohort study.To investigate the long-term outcome following surgery for posttraumatic spinal cord tethering (PSCT).Publicly funded tertiary care center.Patients surgically treated PSCT between 2005-2020 were identified and included. No patients excluded or lost to follow-up. Medical records imaging data retrospectively reviewed.Seventeen Median age was 52 (23-69) years 7 (41%) female. diagnosed at a median of 5.0 (0.6-27) after initial trauma. Motor deficit...
Background and Objectives: Posterior C1-C2 fixation, with trans-articular screws (TAS) or screw-rod-construct (SRC), is the main surgical technique for atlantoaxial instability, can be performed a fluoroscopy-assisted free-handed 3D navigation. This study aimed to evaluate complications, radiological functional outcome in patients treated technique. Materials Methods: A single-center consecutive cohort was conducted of all adult who underwent posterior using TAS CRS, between 2005-2019....
Introduction Mild traumatic brain injury (mTBI) is one of the most common reasons for emergency department (ED) visits. A portion patients with mTBI will develop an intracranial lesion that might require medical or surgical intervention. In these patients, swift diagnosis and management paramount. Several guidelines have been developed to help direct head CT scanning, but they lack specificity, do not consider interactions between risk factors provide individualised estimate risk. The aim...
Tatter, Charles MD; Persson, Oscar MD, PhD; Burström, Gustav Edström, Erik Elmi-Terander, Adrian PhD Author Information
Abstract Background Hemorrhage progression following traumatic brain injury (TBI) is not fully understood, and preventing it would be a potential therapeutic opportunity in TBI management. The aim of this study was to determine how non-operated hemorrhagic lesions progress TBI, affects outcome. Methods This retrospective observational cohort adult patients (≥ 15 years) with moderate-to-severe TBI. volumes were calculated from computed tomography (CT) scans using semi-automated volumetric...