A5101545465- Computational Fluid Dynamics and Aerodynamics
- Combustion and Detonation Processes
- Pluripotent Stem Cells Research
- Mesenchymal stem cell research
- Corneal Surgery and Treatments
- Advanced Sensor Technologies Research
- Reproductive Biology and Fertility
- Sensor Technology and Measurement Systems
- Gas Dynamics and Kinetic Theory
- Ship Hydrodynamics and Maneuverability
- Fluid Dynamics Simulations and Interactions
- Advanced Measurement and Detection Methods
- Automotive and Human Injury Biomechanics
- Fluid Dynamics and Turbulent Flows
- MicroRNA in disease regulation
- Natural product bioactivities and synthesis
- Tissue Engineering and Regenerative Medicine
- Fluid Dynamics and Heat Transfer
- Plasma and Flow Control in Aerodynamics
- Ocular Surface and Contact Lens
- Bioactive natural compounds
- RNA Interference and Gene Delivery
- Acupuncture Treatment Research Studies
- Bone and Joint Diseases
- Urological Disorders and Treatments
Harbin Engineering University
2017-2024
China Shipbuilding Industry Corporation (China)
2020-2023
Chengdu University of Traditional Chinese Medicine
2013-2021
Wuhan University
2009-2019
University of Southern California
2015-2019
Resonance Research (United States)
2019
Mayo Clinic
2019
Southeast University
2014-2018
Wake Forest University
2018
Guilin University of Electronic Technology
2018
The aim of this study was to investigate the effects subconjunctivally administered mesenchymal stem cells (MSCs) on corneal wound healing in acute stage an alkali burn. A burn model generated by placing a piece 3-mm diameter filter paper soaked NaOH right eye 48 Sprague-Dawley female rats. 24 rats were subconjunctival injection suspension 2×10(6) MSCs 0.1 ml phosphate-buffered saline (PBS) day 0 and 3 after other equal amount PBS as control. Deficiencies epithelium area neovascularization...
Autologous urothelial cells are often obtained via bladder biopsy to generate the bio-engineered urethra or bladder, while urine-derived stem (USC) can be by a non-invasive approach. The objective of this study is develop an optimal strategy for urothelium with permeability barrier properties using human USC which could used tissue repair in urinary tract system.USC were harvested from six healthy adult individuals. To optimize differentiation, five different differentiation methods studied....
Purpose.: We explored the underlying mechanisms of doxycycline inhibition corneal angiogenesis.
Abstract MicroRNA‐124 (miR‐124) is an evolutionarily conserved, small, noncoding RNA molecule that participates in the central nervous system (CNS) developmental control of gene expression. In current study, we found Drosophila embryos lacking mir‐124 did not exhibit detectable defects axon growth or CNS development. On other hand, adult mutants showed severe problems locomotion, flight, and female fertility. Furthermore, deficits observed stage could be marginally rescued with elav‐GAL4...
Shock wave interaction with solid wedges has been an area of much research in past decades, but so far very few results have obtained for shock reflection off liquid wedges. In this study, numerical simulations are performed using the inviscid Euler equations and stiffened gas equation state to study transition angles, patterns triple point trajectory angles water Experiments inclined tube also schlieren photography compared simulations. Results show that wedge cases within 5.3 % 9.2 %,...
Research on shock wave mitigation in channels has been a topic of much attention the community. One approach to attenuate an incident is use obstacles various geometries arranged different patterns. This work inspired by study from Chaudhuri et al. (2013), which cylinders, squares and triangles placed staggered non-staggered subsequent columns were used planar wave. Here, we present numerical simulations using obstacle pattern. Instead matrix obstacles, arrangement square or cylindrical...
Compared to stem cells derived from human term umbilical cord, first-trimester cord (hFTUC) exhibit a significantly greater proliferative potential, and more efficiency in terms of their vitro differentiation. In the present study, we investigated whether hFTUC-derived are able differentiate into germ cells. The were first isolated, expanded then cultured differentiation medium containing follicular fluid, follicle-stimulating hormone (FSH)/luteinizing (LH) estradiol for 24 days. During...
A shock wave impact study on open and closed cell foam obstacles was completed to assess attenuation effects with respect different front face geometries of the obstacles. Five types were investigated, while keeping mass obstacle constant. The face, i.e., side where incident impacts, cut in one, two, three or four convergent shapes, results compared a block flat face. Results obtained by pressure sensors located upstream downstream obstacle, addition high-speed schlieren photography. from...
Slamming and longitudinal vibration are two important factors during the preliminary structural design of trimarans. In order to better understand wave-induced loads trimarans in regular waves, hydroelastic experiments were carried out observe wave slamming using a segmented self-propelled model. Details model experimental method provided. Characteristics pressure response measured under different lengths, heights, sailing speeds. Strain gauges attached locations employed investigate...
The aim of the randomized present study was to compare therapeutic efficacy and safety a combination sitagliptin, dipeptidyl peptidase (DPP)-4 inhibitor, plus insulin glargine (GL + sita) with that premixed aspart 30 (NOV) for type 2 diabetes (T2D) patients controlled oral hypoglycemic drugs (HbA1c 7 %-9 %).Sixty-five were (1: 1) GL sita (n = 33) NOV 32) groups treated regimen or twice day 16 weeks. primary endpoint mean change in HbA1c. Secondary endpoints included fasting blood glucose,...
Zuo Gui Wan (ZGW) and You (YGW) are two classic formulas used in clinical treatment of infertility traditional Chinese medicine (TCM). However, the actions remain to be proven at cellular molecular levels. In this study, we investigate whether have any effect on germ cell formation differentiation by culturing rat medicated serums containing YGW or ZGW with stem cells derived from human first trimester umbilical cord. Our results showed that while normal had no significant effects, effects...
Hypersonic vehicles suffer from extreme aerodynamic heating during flights, especially around the area of leading edge due to its small curvature. Therefore, flush air data sensing (FADS) system has been developed perform accurate measurement parameters. In present study, method develop FADS algorithms with fail-operational capability for a sharp-nosed hypersonic vehicle is provided. To be specific, implemented 16 airframe-integrated pressure ports used as case study. Numerical simulations...
This study aimed to understand the effects of single nucleotide polymorphisms (SNPs) in UGT1A1, SLCO1B3, ABCB1, ABCC2, ABCG2, and ORM1 on pharmacokinetics (PK) (plasma concentration) pharmacodynamics (PD) (blood pressure) telmisartan Chinese patients.58 Han patients (aged 45 - 72 years) with mild moderate essential hypertension were included received 80 mg/day for 4 weeks. The plasma concentration genetic variants determined by LC/MS/MS MALDI-TOF mass spectrometry, respectively....
Abstract Retinoic acid (RA) and oleanolic (OA) were studied about their potential to induce mouse embryonic stem cell R1/E (MESC‐R1/E) differentiate toward germ cells. Embryoid bodies (EBs) first formed from MESC‐R1/E EBs allowed attach the bottoms of normal cell‐culturing plate grow. Then, different compounds including RA, OA so on respectively added differentiate. After 72 h, microscopy images taken for all interventions, then total RNAs extracted, cDNAs synthesized real‐time fluorescence...
To investigate the effects of Zuogui pill, Yougui pill and relative compositions on differentiation towards germ cells stem cells.The rat drug sera for common composition were prepared respectively as experimental drugs; mouse embryonic cell 1B10 (MESC-1B10) was used representative cells; above to intervene MESC-1B10 process traced by microscopy imaging; after 72 h intervention, RNAs extracted from different intervened MESC-1B10, cDNAs synthesized immediately finally Real-time quantitative...