A5100727697- Hemoglobin structure and function
- Obsessive-Compulsive Spectrum Disorders
- Innovations in Medical Education
- Heme Oxygenase-1 and Carbon Monoxide
- Empathy and Medical Education
- Eating Disorders and Behaviors
- Ion channel regulation and function
- Neuroscience of respiration and sleep
- Nitric Oxide and Endothelin Effects
- Erythrocyte Function and Pathophysiology
- Autism Spectrum Disorder Research
- Neuroendocrine regulation and behavior
- Medical Education and Admissions
- Traumatic Brain Injury and Neurovascular Disturbances
- Evolutionary Psychology and Human Behavior
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- High Altitude and Hypoxia
- Healthcare professionals’ stress and burnout
- Gastrointestinal motility and disorders
- Genetics, Aging, and Longevity in Model Organisms
- Birth, Development, and Health
- Substance Abuse Treatment and Outcomes
- Lipid Membrane Structure and Behavior
- Epigenetics and DNA Methylation
- Psychological and Temporal Perspectives Research
Yonsei University
2015-2024
Chung-Ang University
2024
Seoul National University
2024
Keimyung University
2023
Brown University
2004-2022
Severance Hospital
2014-2022
Kyungpook National University
2012-2022
Institute of Behavioral Sciences
2016-2022
CHA University
2021
CHA Bundang Medical Center
2021
The development and implementation of a systematic program evaluation framework is critical for improving the quality undergraduate medical education. At Yonsei University College Medicine, we established following five domains that encompass various aspects educational experiences: (1) preclinical curriculum; (2) clinical (3) environment, resources, systems; (4) performance students graduates outcomes; (5) outcomes curriculum. Specific indicators were designed within these validated through...
Circadian preference has been considered related with impulsivity. The purpose of the present study was to evaluate relationship between circadian typology and impulsivity measured by Barratt Impulsivity Scale (BIS), sensation-seeking Sensation Seeking - Form V (SSS-V) response inhibition elicited GO/NO-GO paradigm. A total 503 Korean healthy college students (288 males 215 females) completed Composite Morningness (CSM) for BIS SSS-V risk taking, respectively. subset 142 subjects...
Early life stress (ELS) leads to increased susceptibility serious psychiatric problems such as alcohol dependence, but the mechanisms through which ELS affects dependence are unclear. We investigated mediating role of multi-dimensional impulsivity in associations between and dependence. 330 male patients with (mean age = 48.39) completed self-rating scales several self-report measures well balloon analogue risk task (BART). After classifying different dimensions using factor analysis,...
In March 2006, a workshop sponsored by the National Heart, Lung, and Blood Institute was convened to identify role of basic science research in clarifying issues that are impeding progress development hemoglobin‐based oxygen carrying (HBOC) solutions. These discussions resulted consensus that, although HBOCs have shown clinical promise, various side effects inhibited further regulatory approval, with cardiovascular events being particular concern. As consequence, participants focused on...
Oxytocin is an important neuromodulator involved in cognition and socio-emotional processing that exerts its central activities via oxytocin receptors. Epigenetic alterations the receptor gene (OXTR) may be a molecular mechanism pathogenesis of obsessive-compulsive disorder (OCD). This study investigated association between OXTR DNA methylation OCD status Korean population. Quantitative leukocyte levels three cytosine-phosphate-guanine (CpG) sites 5' untranslated region (UTR) exon 2 eight...
Telomere length has been suggested to be a cellular marker for age-related diseases as well psychosocial stress. The present study investigated whether telomere is associated with post-traumatic stress disorder (PTSD) among veterans exposed combat trauma in the Vietnam War. potentially factors on aging were considered. Korean male (n = 122) and without 120) PTSD included leukocyte was measured quantitative PCR-based technique. As whole, no significant difference found between non-PTSD...
MELD-Na (model for end-stage liver disease with incorporation of serum sodium) was suggested to provide better survival prediction than MELD alone patients end stage disease. However, there is no data verifying the usefulness predicting short term mortality cirrhotic in Korea. This study aimed determine whether would be more accurate other scoring systems such as Child-Turcotte-Pugh (CTP) or MELD.Data from 355 admitted due cirrhosis were retrospectively reviewed. The cumulative rates...
서 론 강박장애는 침습적이고 반복적으로 떠오르는 부적절한 생각을 일컫는 강박사고와 이를 중화하여 불안을 감소시키 려는 지속적이고 반복적인 행동을 강박행동을 특징 으로 하는 질환으로, 이 질환을 앓는 환자들은 자신의 증상 인해 큰 고통을 느끼며 장애를 초래할 만큼 심각한 사 회적, 직업적인 기능 저하를 야기한다
Functional dyspepsia (FD) and irritable bowel syndrome (IBS) are common gastrointestinal (GI) diseases; however, there is frequent overlap between FD IBS patients.Emerging evidence links the activation of corticotropin releasing factor (CRF) receptors with stress-related alterations gastric colonic motor function.Therefore, we investigated effect peripheral CRF peptide water avoidance stress (WAS) on upper lower GI transit in guinea pigs.Dosages 1, 3, 10 μg/kg were injected intraperitoneally...
Evidence from literature supports the existence of associations between serotonin-related genetic variants and obsessive-compulsive disorder (OCD), but few studies have explored involvement serotonin receptor type 3 genes (HTR3) in OCD. To identify whether HTR3 variability affects an individual's susceptibility to OCD, we examined 10 596 individuals with OCD 599 controls. A significant difference existed genotypic distribution HTR3B variant rs1176744 controls (odds ratio [OR] = 0.74, 95%...
Suicidality in obsessive-compulsive disorder (OCD) is underestimated and it important for clinicians to understand the factors that contribute suicidal ideation. The present study aimed estimate a network of core clinical symptoms OCD including obsessions, compulsions, (OC) symptom dimensions, depressive symptoms, psychological traits, examine which ideation patients with primary diagnosis disorder.A total 444 were assessed Yale-Brown Obsessive-Compulsive Scale, Montgomery-Asberg Depression...
Phospholamban is the regulator of Ca2+-ATPase in cardiac sarcoplasmic reticulum (SR). The mechanism regulation appears to involve inhibition by dephosphorylated phospholamban, and phosphorylation may relieve this inhibition. Fast-twitch skeletal muscle SR does not contain it known whether isoform from be also subject phospholamban a similar manner as isoform. To determine we reconstituted with phosphatidylcholine proteoliposomes. Inclusion was associated significant initial rates Ca2+ uptake...