Hyunchul Kim

ORCID: 0000-0002-9322-725X
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About
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Research Areas
  • Aquaculture Nutrition and Growth
  • Shoulder Injury and Treatment
  • Bone fractures and treatments
  • Stroke Rehabilitation and Recovery
  • Shoulder and Clavicle Injuries
  • Orthopedic Surgery and Rehabilitation
  • Sarcoma Diagnosis and Treatment
  • Spine and Intervertebral Disc Pathology
  • Nerve Injury and Rehabilitation
  • Tuberculosis Research and Epidemiology
  • Pelvic and Acetabular Injuries
  • Pregnancy-related medical research
  • Renal Diseases and Glomerulopathies
  • Lymphoma Diagnosis and Treatment
  • Mycobacterium research and diagnosis
  • Animal Genetics and Reproduction
  • Musculoskeletal pain and rehabilitation
  • Diverse Approaches in Healthcare and Education Studies
  • Hip and Femur Fractures
  • Cancer-related molecular mechanisms research
  • Orthopaedic implants and arthroplasty
  • Gastrointestinal disorders and treatments
  • Botulinum Toxin and Related Neurological Disorders
  • Neuroendocrine Tumor Research Advances
  • Knee injuries and reconstruction techniques

Chosun University
2025

National Health Insurance Service Ilsan Hospital
2021-2024

Korea Institute of Sport Science
2024

University of Illinois Urbana-Champaign
2022

Armed Forces Capital Hospital
2021

Republic of Korea Army
2021

Hallym University Dongtan Sacred Heart Hospital
2018-2021

Hallym University
2019-2021

Centre Hospitalier Intercommunal de Poissy
2021

University of Hertfordshire
2021

Linezolid has antimycobacterial activity in vitro and is increasingly used for patients with highly drug-resistant tuberculosis.We enrolled 41 who had sputum-culture-positive extensively (XDR) tuberculosis not a response to any available chemotherapeutic option during the previous 6 months. Patients were randomly assigned linezolid therapy that started immediately or after 2 months, at dose of 600 mg per day, without change their background regimen. The primary end point was time...

10.1056/nejmoa1201964 article EN New England Journal of Medicine 2012-10-18

Robot-assisted stroke rehabilitation has become popular as one approach to helping patients recover function post-stroke. Robotic requires four important elements match the robot patient: realistic biomechanical robotic elements, an assistive control scheme enabled through human-robot interface, a task oriented program based on principles of plasticity, and objective assessment tools monitor change. This paper reports randomized clinical trial utilizing complete robot-assisted system for...

10.1109/tnsre.2012.2207462 article EN IEEE Transactions on Neural Systems and Rehabilitation Engineering 2012-07-28

In Brief Study Design. vivo experiments to examine physiologic consequences and in vitro tests determine immediate biomechanical effects of anular injury by needle puncture. Objective. To whether a relationship exists between induction degenerative changes anulus fibrosus (AF) compromised disc function according size. Summary Background Data. Various studies intervertebral mechanics, degeneration, regeneration involve the creation defect (AF). However, impact puncture, itself, on health are...

10.1097/brs.0b013e31819c09c4 article EN Spine 2009-05-01

To compare the biomechanical performance of a cephalomedullary nail (CMN), proximal femoral locking plate, and 95° angled blade plate in comminuted subtrochanteric fracture model.A model was created with 2-cm gap below lesser trochanter 15 pairs human cadaveric femora confirmed to be nonosteoporotic. The were randomized treatment one previously mentioned 3 devices. Each tested under incrementally increasing cyclic load up 90,000 cycles from 50% 250% body weight simulate progressive bearing...

10.1097/bot.0b013e3182254ea3 article EN Journal of Orthopaedic Trauma 2012-01-12

ABSTRACT Fluoroquinolones (FQ) are important second-line drugs to treat tuberculosis; however, FQ resistance is an emerging problem. Resistance has been mainly attributed mutations in a 21-bp region of the Mycobacterium tuberculosis gyrA gene, often called quinolone resistance-determining (QRDR). We have developed simple, rapid, and specific assay detect QRDR mutations. The amplifies M. asymmetrical PCR followed by probing with two sloppy molecular beacons (SMBs) spanning entire QRDR....

10.1128/jcm.02271-10 article EN Journal of Clinical Microbiology 2010-12-30

Abstract Introduction Degeneration of the intervertebral disc (IVD) is characterized by marked degradation and restructuring annulus fibrosus (AF). Although several matrix metalloproteinases (MMPs) have been found to be more prevalent in degenerate discs, their coordination function within context disease process are still not well understood. In this study, we sought determine whether MMP-2 associated with degenerative changes AF identify manner which cells use MMP-2. Methods Two...

10.1186/ar4224 article EN cc-by Arthritis Research & Therapy 2013-04-27

BACKGROUND Peri-operative hypothermia and shivering are frequent events in patients during caesarean delivery under spinal anaesthesia. OBJECTIVE We assessed the efficacy of combined pre-anaesthetic forced-air warming combination with warmed intravenous fluid infusion for preventing DESIGN A randomised controlled study. SETTING tertiary care teaching hospital from July 2017 to April 2018. PATIENTS total 50 pregnant women, American Society Anaesthesiologists physical status 2, aged 20 45...

10.1097/eja.0000000000000990 article EN European Journal of Anaesthesiology 2019-06-01

ABSTRACT Rifampin resistance in Mycobacterium tuberculosis is largely determined by mutations an 80-bp rifampin determining region (RRDR) of the rpoB gene. We developed a rapid single-well PCR assay to identify RRDR mutations. The uses sloppy molecular beacons probe asymmetric M. melting temperature ( T m ) analysis. A three-point code generated which distinguishes wild-type from mutant DNA sequences approximately 2 h. was validated on synthetic oligonucleotide targets containing 44 most...

10.1128/jcm.00143-12 article EN Journal of Clinical Microbiology 2012-04-27

Programmed cell death ligand‐1 ( PD ‐L1) detection assays have not been standardized for patients with colorectal cancer, and the prognostic value of ‐L1 expression is unclear. We compared patterns in cancer samples using various immunohistochemical 3 primary antibodies (assay 1, MIH 1; assay 2, E1L3; 3, 22C3) investigated implication each. Additionally, gene amplification was evaluated FISH. The percentage scorings positivity rates differed; degrees correlation concordance between 2 were...

10.1111/cas.13716 article EN cc-by-nc-nd Cancer Science 2018-06-27

Allograft tendons are frequently used for ligament reconstruction about the knee, but they entail availability and cost challenges. The identification of other tissues that demonstrate equivalent performance to preferred would improve limitations. Hypothesis/Purpose: We compared biomechanical properties 4 soft tissue allograft tendons: tibialis anterior (TA), posterior (TP), peroneus longus (PL), semitendinosus (ST). hypothesized be similar when standardized by looped diameter.Controlled...

10.1177/0363546516671944 article EN The American Journal of Sports Medicine 2016-11-11

Objective: It has been proposed that 2.5 cm of diastasis the symphysis pubis corresponds with injury to anterior sacroiliac ligament and differentiates Young-Burgess anteroposterior compression Type I II pelvic ring injuries. We hypothesized if a pelvis greater than diastasis, ligaments are disrupted floor failed. Methods: Pure torsional moment was applied cadaveric human pelves hemipelvis either unconstrained (n = 10) or constrained move only in plane rotation 10). recorded displacement...

10.1097/bot.0b013e3181cff42c article EN Journal of Orthopaedic Trauma 2010-09-25

The local peritoneal effects of low-glucose degradation product (GDP)-containing dialysis fluid (PDF) have been extensively described. However, the systemic prolonged prescription these solutions are unknown. This study aimed to evaluate neutral pH and low-GDP PDF on inflammation endothelial dysfunction markers in (PD) patients. is a multicenter, open labeled, randomized controlled trial including one hundred fifty-two patients initiating continuous ambulatory for end-stage renal disease...

10.1093/ndt/gfr451 article EN Nephrology Dialysis Transplantation 2011-08-22

Distant metastasis and recurrence are major prognostic factors associated with breast cancer. Both lymphovascular invasion (LVI) blood vessel (BVI) important routes for to regional lymph nodes systemic metastasis. Despite the importance of vascular as a factor, application histopathological criterion is controversial. The aim this study was distinguish LVI from BVI in prognosis cancer using an endothelial subtype specific immunohistochemical stain (podoplanin, D2-40, CD31).Sections 80...

10.4048/jbc.2011.14.2.104 article EN cc-by-nc Journal of Breast Cancer 2011-01-01

Recent technological advances have led to analyses of the delta neutrophil index (DNI), which reflects fraction circulating immature granulocytes, using specific automated blood cell analyzers. We evaluated significance DNI as a prognostic marker for early severity in patients with acute cholangitis.We retrospectively analyzed initially diagnosed cholangitis at emergency department admission, followed by diagnostic confirmation, during set period. The was determined on each day...

10.1097/shk.0000000000000722 article EN Shock 2016-08-24
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