- Acoustic Wave Resonator Technologies
- Pluripotent Stem Cells Research
- 3D Printing in Biomedical Research
- Cellular Mechanics and Interactions
- Gas Sensing Nanomaterials and Sensors
- Microfluidic and Bio-sensing Technologies
- Analytical Chemistry and Sensors
- Advanced Chemical Sensor Technologies
- Ultrasonics and Acoustic Wave Propagation
- Medical Imaging Techniques and Applications
- Tissue Engineering and Regenerative Medicine
- Developmental Biology and Gene Regulation
- Mechanical and Optical Resonators
- Magnetic Properties and Applications
- Cancer Cells and Metastasis
- Advanced Fiber Optic Sensors
- CRISPR and Genetic Engineering
- Advanced Radiotherapy Techniques
- Renal and related cancers
- Magnetic properties of thin films
- Single-cell and spatial transcriptomics
- Non-Destructive Testing Techniques
- Medical Image Segmentation Techniques
- Congenital heart defects research
- Hippo pathway signaling and YAP/TAZ
Institute of Acoustics
2015-2025
Chinese Academy of Sciences
2014-2025
University of Michigan
2016-2024
Chongqing University of Technology
2022-2024
Chongqing University
2023
University of Chinese Academy of Sciences
2023
Ann Arbor Center for Independent Living
2017
Abstract Primordial germ cells (PGCs) are the embryonic precursors of sperm and eggs. They transmit genetic epigenetic information across generations. Given prominent role germline defects in diseases such as infertility, detailed understanding human PGC (hPGC) development has important implications reproductive medicine studying evolution. Yet, hPGC specification remains an elusive process. Here, we report induction hPGC-like (hPGCLCs) a bioengineered pluripotent stem cell (hPSC) culture...
A human neural tube development model with proper dorsal-ventral patterning is accomplished using stem cells.
Acoustic impedance enables many interesting acoustic applications. However, for gas sensing is rare and difficult. Here we introduce a micro-nano surface wave (SAW) chip based on the effect to achieve ultra-fast wide-range sensing. We theoretically established relationship between load SAW attenuation, analyzed influence of propagation loss under different gas/humidity media. Experimental measurements reveal that differences in generated by gases trigger can (0-100 v/v%) monitoring, with...
PdNi alloy thin films demonstrate exceptional hydrogen sensing performance and exhibit significant potential for application in surface acoustic wave (SAW) sensors. However, the long-term stability of SAW H2 sensors utilizing as catalysts experiences a substantial decrease during operation. In this paper, X-ray photoelectron spectroscopy (XPS) is employed to investigate failure mechanisms under operational conditions. The XPS analysis reveals that formation PdO species on plays crucial role...
A temperature-compensated surface acoustic wave (SAW)-based current sensor was proposed in this contribution, composed of a chip made by SAW delay line patterns on SiO2/128° YX LiNbO3 piezoelectric substrate, magnetostrictive FeCo film deposited the propagation path, and corresponding differential oscillation configuration. The coating produced strain under magnetic field generated applied current, leading to linearity changes form velocity change. frequency shift used evaluate tested...
Mechanical forces play critical roles in influencing human embryonic stem cell (hESC) fate. However, it remains largely uncharacterized how local mechanical influence hESC behavior vitro. Here, we used an ultrasound (US) technique, acoustic tweezing cytometry (ATC), to apply targeted cyclic subcellular hESCs via integrin-bound microbubbles (MBs). We found that ATC-mediated applied for 30 min near the edge of a colony induced immediate global responses throughout colony, suggesting importance...
A novel wireless and passive surface acoustic wave (SAW) based temperature-compensated vibration sensor utilizing a flexible Y-cut quartz cantilever beam with relatively substantial proof mass two one-port resonators is developed. One resonator acts as the sensing device adjacent to clamped end for maximum strain sensitivity, other one used reference located on temperature compensation through differential approach. Vibration directed flex cantilever, inducing relative changes in propagation...
The influences of environment, such as temperature, humidity and interfering gases, on the performance a surface acoustic wave (SAW) sensor in detection 2-chloroethyl ethyl sulfide (CEES) were invested. 150 MHz SAW dual delay lines used, coated with poly(epichlorohydrin) (PECH) thin layer, CEES was detected under different concentrations. Linear correlation between frequency-shift exposure time to could be observed, limit low 1.5 mg m-3. Under temperature (0-50 C°) (30-80% RH) conditions, by...
Purpose This paper aims to give an overview about the state of wireless passive surface acoustic wave (SAW) gas sensor used in detection chemical vapor. It also discusses a variety different architectures including delay line and array for detection, it is considered that this technology has good application prospect. Design/methodology/approach The authors most SAW methods sensing, such as CO2, CO, CH4, C2H4, NH3, NO2, et al. , principles, design procedures technological issues are...
A high-sensitive wireless and passive surface acoustic wave (SAW) humidity sensor operating at 433 MHz was designed developed. SiO2 thin film with large specific employed as the humidity-sensitive interface deposited along sensing area of SAW device patterned by a reflective delay line using plasma-enhanced chemical vapor deposition (PECVD) to build chip. Coupling modes (COMs) model utilized simulate prior fabrication achieve low time-domain insertion high signal-to-noise ratio (SNR). The...
The role of Notch signaling in regulating angiogenesis is examined using a 3D biomimetic microfluidic device and nanobiosensors.
A new wireless and passive surface acoustic wave (SAW)-based chemical sensor for organophosphorous compound (OC) detection is presented. 434 MHz reflective delay line configuration composed by single phase unidirectional transducers (SPUDTs) three shorted reflectors was fabricated on YZ LiNbO₃ piezoelectric substrate as the element. thin fluoroalcoholpolysiloxane (SXFA) film acted sensitive interface deposited onto SAW propagation path between second last of device. The first reflector used...