A5047196485- Dental Health and Care Utilization
- Oral microbiology and periodontitis research
- Head and Neck Cancer Studies
- Medical Imaging Techniques and Applications
- Health Literacy and Information Accessibility
- Radiomics and Machine Learning in Medical Imaging
- Antimicrobial Peptides and Activities
- Medical Research and Treatments
- Dysphagia Assessment and Management
- Polydiacetylene-based materials and applications
- Nutrition and Health in Aging
- Hepatitis B Virus Studies
- Graphene research and applications
- Dental Trauma and Treatments
- Thyroid Cancer Diagnosis and Treatment
- Biosensors and Analytical Detection
- Lung Cancer Diagnosis and Treatment
- Gut microbiota and health
- Mycobacterium research and diagnosis
- Carbon Nanotubes in Composites
- Monoclonal and Polyclonal Antibodies Research
- Protein purification and stability
- Cervical Cancer and HPV Research
- Dental Research and COVID-19
- Dental materials and restorations
Sichuan University
2010-2025
Institute for Biomedicine
2025
State Key Laboratory of Oral Diseases
2024
University of South China
2023
Secondary caries caused by dental plaque is one of the major reasons for high failure rate resin composite restoration. Although antimicrobial agent–modified restoration systems have been researched years, few reported intelligent anticaries materials could respond to change oral environment and help keep eubiosis. Herein, we report tertiary amine (TA)–modified adhesives (TA@RAs) with pH-responsive antibacterial effect reduce occurrence secondary caries. Two kinds newly designed TA monomers...
Objective To investigate the associations of oral microbiome status with diabetes characteristics in elderly patients type 2 mellitus.
Diabetes with its highly prevalence has become a major contributor to the burden of health care costs worldwide. Recent unequivocal evidence revealed bidirectional link between oral and diabetes. In this study, effects Oral Health Promotion Program (OHPP) on hygiene, health-related quality life glycated haemoglobin (HbA1c) levels in diabetic elderly were examined. Moreover, microbial changes saliva microbiota community also emphatically investigated. A quasi-experiment was conducted...
<title>Abstract</title> Elucidating antibody sequences by mass spectrometry (MS)-based <italic>de novo</italic> sequencing is essential but challenging. Herein, we propose XA-Novo, an accurate, robust, high-throughput solution that integrates a single-pot multi-enzymatic gradient digestion method with beam search-based Fusion assembler to accurately decipher complete at both the sample preparation stage and data analysis phase. We first benchmark XA-Novo using from multiple known antibodies...
Oral health literacy (OHL) might have an impact on oral outcomes. Currently, relatively few related studies been conducted among older people. The aim of this study was to explore the impacts OHL outcomes in adults a cross-sectional design. From November December 2023, through utilization cluster sampling approach, questionnaire survey carried out elderly patients visiting Prosthodontics Department West China hospital Stomatology. Data were collected general information questionnaire,...
This cross-sectional study aims to explore the association between oral health status and cognitive function in Chinese elderly individuals. The survey participants were composed of people aged≥60 who admitted West China Hospital Stomatology, Sichuan University from August 2022 March 2024. They divided into a impairment (CI) group healthy control (HC) according Montreal Cognitive Assessment (MoCA) score. General information indicators all collected. Independent sample t-test chi-square test...
To identify the presence of mouse beta-defensin 3 (Mbd3) (the human homologue 2) in different tissues and to define antimicrobial properties recombinant MBD3 (rMBD3) against a panel pathogens.Mbd3 gene expression before or after lipopolysaccharide (LPS) injection was compared by semi-quantitative RT-PCR. This analysis demonstrated that epithelial mucosal expressed Mbd3 independent LPS stimulation. Evaluation rMBD3 determined assessing median inhibition concentration (IC(50)), minimal...
Abstract Aims and Objectives To investigate the oral health literacy (OHL) of nurses explore factors affecting their OHL. Background OHL is important for improving outcomes. Nurses' may affect themselves, families, patients. Few studies have examined its related among nurses. Design A cross‐sectional design following STROBE guideline. Methods total 449 were recruited from tertiary hospitals in minority areas southwest China. The participants completed an online questionnaire, which contained...
<title>Abstract</title> Background Diabetes, which is highly prevalent, has become a major contributor to the burden of health care costs worldwide. Recent unequivocal evidence revealed bidirectional link between oral and diabetes. In this study, effects Oral Health Promotion Program (OHPP) on hygiene, health-related quality life glycated haemoglobin (HbA1c) levels were examined. At same time, microbial changes in saliva microbiota community also investigated. Methods A quasi-experiment was...
A series of carbon-rich products with three-dimensional (3D) grape-bunch structure have been synthesised by the hydrothermal carbonisation saccharides (glucose, sucrose and starch) assistance hydroxylated multi-wall carbon nanotubes (MWCNTs). The carbonaceous spheres are regarded as ‘grapes’; MWCNTs were used connected wires that could be embedded into ‘grapes’ via self-assembling hydrophilic groups to form a 3D-grape-bunch structure. characterised scanning electron microscopy,...