Ajesh B. Maharaj
A5028549127- Rheumatoid Arthritis Research and Therapies
- Autoimmune and Inflammatory Disorders Research
- Spondyloarthritis Studies and Treatments
- Psoriasis: Treatment and Pathogenesis
- Vasculitis and related conditions
- Health Systems, Economic Evaluations, Quality of Life
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Patient-Provider Communication in Healthcare
- Systemic Lupus Erythematosus Research
- Delphi Technique in Research
- Musculoskeletal Disorders and Rehabilitation
- Viral Infections and Immunology Research
- Chronic Lymphocytic Leukemia Research
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Urticaria and Related Conditions
- Bartonella species infections research
- Neurogenetic and Muscular Disorders Research
- Peripheral Neuropathies and Disorders
- Cytokine Signaling Pathways and Interactions
- Hepatitis C virus research
- Otitis Media and Relapsing Polychondritis
- Glycogen Storage Diseases and Myoclonus
- Neurological and metabolic disorders
- Heparin-Induced Thrombocytopenia and Thrombosis
- Tattoo and Body Piercing Complications
University of KwaZulu-Natal
2014-2025
Walter Sisulu University
2024-2025
Nelson Mandela Academic Hospital
2025
BroadReach Healthcare (South Africa)
2021
Amsterdam UMC Location University of Amsterdam
2014-2018
University of Amsterdam
2014-2018
University of Trinidad and Tobago
2016
Abstract Therapy for polymyalgia rheumatica (PMR) varies widely in clinical practice as international recommendations PMR treatment are not currently available. In this paper, we report the 2015 European League Against Rheumatism (EULAR)/American College of Rheumatology (ACR) management PMR. We used Grading Recommendations, Assessment, Development and Evaluation (GRADE) methodology a framework project. Accordingly, direction strength based on quality evidence, balance between desirable...
Therapy for polymyalgia rheumatica (PMR) varies widely in clinical practice as international recommendations PMR treatment are not currently available. In this paper, we report the 2015 European League Against Rheumatism (EULAR)/American College of Rheumatology (ACR) management PMR. We used Grading Recommendations, Assessment, Development and Evaluation (GRADE) methodology a framework project. Accordingly, direction strength based on quality evidence, balance between desirable undesirable...
Methylenetetrahydrofolate reductase (MTHFR) gene is involved in homocysteine and folic acid metabolism. Tumour suppressor protein TP53 maintains cellular genetic integrity. To date, no studies associated the MTHFR C677T rs1801133 Pro72Arg rs1042522 with CRP levels methotrexate (a antagonist) treatment outcomes psoriatic arthritis (PsA) patients. The present study aimed to investigate whether variants influences South African Indian Caucasian PsA patients (n=114) healthy controls (n=100) were...
Psoriatic arthritis (PsA) is a challenging heterogeneous disease. The European League Against Rheumatism (EULAR) and the Group for Research Assessment of Psoriasis PsA (GRAPPA) last published their respective recommendations management in 2015. However, these guidelines are primarily based on studies conducted resource replete countries may not be applicable Americas (except Canada USA) Africa. We sought to adapt existing regions under auspices International Associations Rheumatology...
Abstract Background It is plausible that optimal cardiovascular disease (CVD) risk management differs in patients with rheumatoid arthritis (RA) from low or middle income compared to high populations. This study aimed at producing evidence-based points consider for CVD prevention South African RA patients. Methods Five rheumatologists, one cardiologist and epidemiologist experience patients, as well two patient representatives, health professionals radiologist, rheumatology fellow 11...
Psoriasis and psoriatic arthritis (PsA) are inflammatory associated autoimmune disorders. MicroRNA (miR)-146a plays a crucial role in regulating inflammation. A single nucleotide polymorphism the miR-146a gene (rs2910164), aberrantly alters its expression linked with pathogenesis of several disorders, including psoriasis PsA. In South Africa, PsA extremely rare indigenous African population most common both Indian Caucasian population. The aim this study was to investigate whether rs2910164...
Objective. To evaluate the sensitivity and specificity of classification criteria for psoriatic arthritis (PsA) in a South African cohort. Methods. Data from consecutive patients with PsA other chronic inflammatory arthritides were collected prospectively. Subjects classified according to criteria. The each group compared clinical diagnosis made by rheumatologist. Results. European Spondylarthropathy Study Group exhibited lowest followed Moll Wright ClASsification Psoriatic ARthritis...
<h3>Background</h3> The European League Against Rheumatism (EULAR) and the Group for Research Assessment of Psoriasis PsA (GRAPPA) updated their respective recommendations management in 2015. However, these guidelines are primarily based on studies conducted resource replete countries; hence they may not be applicable to countries Central South America, Africa. Therefore, new ILAR have been developed regions adapted from existing recommendations. <h3>Objectives</h3> To establish poor...
Background. Although psoriatic arthritis (PsA) is a well-documented clinical entity, epidemiological, and radiological studies of South African (SA) patients are scarce. Objectives. To assess clinical, biochemical features in single-centre SA cohort. Methods. We conducted prospective assessment the 384 consecutive with PsA seen at rheumatology clinic Prince Mshiyeni Memorial Hospital, Durban, SA, between January 2007 December 2013. Patients were assessed enrolment 6 months after enrolment....