A5047243292- Ocular Surface and Contact Lens
- Glaucoma and retinal disorders
- Traumatic Brain Injury Research
- Corneal surgery and disorders
- Urticaria and Related Conditions
- Medication Adherence and Compliance
- Ocular Infections and Treatments
- Health Systems, Economic Evaluations, Quality of Life
- Corneal Surgery and Treatments
- Rheumatoid Arthritis Research and Therapies
- Pharmacological Effects and Toxicity Studies
- Epilepsy research and treatment
- Cardiac Arrest and Resuscitation
- Traumatic Brain Injury and Neurovascular Disturbances
- Lymphoma Diagnosis and Treatment
- Patient-Provider Communication in Healthcare
- Education Systems and Policy
- Pharmaceutical Practices and Patient Outcomes
- Delphi Technique in Research
- Pharmaceutical studies and practices
- Contact Dermatitis and Allergies
- Ethics in medical practice
- Advanced Drug Delivery Systems
- Tribology and Lubrication Engineering
- Pharmacological Effects and Assays
University of Canberra
2019-2023
Royal North Shore Hospital
2000-2021
ACT Government
2019
Johns Hopkins University
2019
Australian National University
2019
The University of Sydney
2019
Ingham Institute
2019
Children's Hospital at Westmead
2019
Cal Humanities
2019
Canberra Hospital
2019
Phenytoin is the recommended second-line intravenous anticonvulsant for treatment of paediatric convulsive status epilepticus in UK; however, some evidence suggests that levetiracetam could be an effective and safer alternative. This trial compared efficacy safety phenytoin management epilepticus.This open-label, randomised clinical was undertaken at 30 UK emergency departments secondary tertiary care centres. Participants aged 6 months to under 18 years, with requiring treatment, were...
Contamination of contact lens cases has been associated with the production adverse responses in eye during wear. This study aimed to evaluate contamination rate and types microbes contaminating use disinfecting solutions silicone hydrogel lenses.Two hundred thirty-two participants were allocated one or more groups. The wore three lenses used four solutions. Cases collected after for 1 month sent routine microbial testing. evaluated.Between 76 92% all contaminated. Use different did not...
ABSTRACT Lacryglobin has been identified in human tears. This protein high sequence homology to the mammaglobins, proteins upregulated breast cancer and metastasis. In order investigate utility of tear screening for cancer, samples were collected from patients with different types compared controls. Tear taken five controls eight breast, six lung, colon, one prostate three ovary patients. Tears analysed using 2‐D gel electrophoresis ( n = 25) 1‐D 3). was present following percentage...
Differences in the metabolic fate of antithyroid drugs influence optimal frequency administration and their therapeutic efficacy. (35)S propylthiouracil differed from imidazoles (carbimazole methimazole) more rapid absorption excretion shorter biological half-life plasma former. Renal function may have a important on than thyroid status. Further work is required to determine for each compound.
Purpose. To correlate clinical responses during contact lens wear with the amount of protein or cholesterol extracted from lenses after wear. Methods. Clinical parameters, including adverse response rates and corneal staining, symptomatology rating were collected a series tests comprising four different silicone hydrogel multipurpose solutions. test for correlates, total daily compared statistically to parameters. Results. The (p = 0.008) 0.01) was higher those subjects who showed...
The aim of this study was to investigate the relationship between solution-induced corneal staining (SICS) and silicone hydrogel contact lens comfort vision.A retrospective analysis a series open-label studies were conducted with 24 groups approximately 40 participants, each wearing 1 6 lenses 4 care products bilaterally for 3 months daily wear. presence SICS subjective ocular ratings collected at 2 weeks months.A total 1,051 participants enrolled. rated significantly less favorably than did...
This study aimed to identify and prioritize factors important patients caregivers with regard medication adherence in gout, osteoporosis (OP), rheumatoid arthritis (RA) describe the reasons for their decisions.Patients OP, RA caregivers, purposively sampled from 5 rheumatology clinics Australia, identified ranked that they considered using nominal group technique discussed decisions. An importance score (IS; scale 0-1) was calculated, qualitative data were analyzed thematically.From 14 focus...
Background Convulsive status epilepticus is the most common neurological emergency in children. Its management important to avoid or minimise morbidity and death. The current first-choice second-line drug phenytoin (Epanutin, Pfizer Inc., New York, NY, USA), for which there no robust scientific evidence. Objective To determine whether levetiracetam (Keppra, UCB Pharma, Brussels, Belgium) more clinically effective intravenous treatment of paediatric convulsive help better inform its...
Purpose. Microbial keratitis (MK) is a serious sight-threatening complication occurring with and without contact lens wear. The task of diagnosing MK difficult because each presentation the disease different can be mistaken for noninfectious ulcers such as peripheral ulcer (CLPU). purpose this article to present case report initially diagnosed CLPU. Case Report. We incidence 21-year-old female presenting signs symptoms in her left eye, which suggested At 24-h follow-up, contrary expected...
Objective. The OMERACT-Adherence meeting was convened to discuss the conceptual and methodological challenges in developing a core domain set (Adherence-CDS) for trials of interventions medication adherence rheumatology. Methods. Forty participants from nine countries participated. Results. Four ideas emerged: trials, Adherence-CDS could include condition-specific CDS; many factors affect are intervention targets, contextual factors, or outcome domains; is critical factor drug trials;...
Abstract The thrill to go fast and push boundaries is something that many seek. From John Stapp’s rocket sled at Edwards Air Force Base in the late 1950’s todays’ Formula 1 drivers, “need for speed” broadcast across TV screens weekly. So too are horror stories of crashes, over 300km/hr. Yet continues. It appears higher faster rollercoaster, better. This leads several questions. How does brain stand up speed G-forces? Do Newton’s Laws still have reference today’s world? There has been much...
A double-blind randomized clinical study was conducted to determine whether nicardipine hydrochloride a useful treatment for dry eye.We examined its effect on the tear film, ocular surface and comfort. Nicardipine hydrochloride, 3-isobutyl-1-methylxanthine pilocarpine were dissolved in an artificial vehicle applied topically one eye of 12 subjects separate days. Ocular physiology, comfort volume assessed. The trial repeated with aqueous gel vehicle. Tears collected assessed protein...
Purpose. To determine risk-taking propensity of optometrists and the association with volume contact lens practice prescribing profile. Other factors associated high practitioner risk taking larger practices were also investigated. Methods. Sixty-four practitioners recruited through Australian professional associations. Practitioners completed a survey rated importance for lens-related microbial keratitis on decisions wearer advice (prescribing profile). Demographics number wearers seen per...