- Endodontics and Root Canal Treatments
- Oral microbiology and periodontitis research
- Dental Radiography and Imaging
- Dental Health and Care Utilization
- Dental Education, Practice, Research
- Bacterial biofilms and quorum sensing
- Drilling and Well Engineering
- Dental Trauma and Treatments
- Biosensors and Analytical Detection
- Streptococcal Infections and Treatments
- Salivary Gland Disorders and Functions
- Dental materials and restorations
- Oral Health Pathology and Treatment
- Otolaryngology and Infectious Diseases
- Infective Endocarditis Diagnosis and Management
- Sinusitis and nasal conditions
- Dental Anxiety and Anesthesia Techniques
- Health and Medical Education
- Photodynamic Therapy Research Studies
- Occupational health in dentistry
- Gut microbiota and health
- Antibiotic Resistance in Bacteria
- Forensic Anthropology and Bioarchaeology Studies
- Opioid Use Disorder Treatment
- Cardiovascular and Diving-Related Complications
University of Copenhagen
2011-2025
Malmö University
2023-2024
Lund University
2024
University of Iceland
2023
University of Oslo
2023
Clinical Research Management
2016
Regenerative Medicine Institute
2016
This position statement on the management of deep caries and exposed pulp represents consensus an expert committee, convened by European Society Endodontology (ESE). Preserving in a healthy state with sustained vitality, preventing apical periodontitis developing minimally invasive biologically based therapies are key themes within contemporary clinical endodontics. The aim this was to summarize current best evidence diagnosis classification caries-induced pulpal disease, as well indicating...
Bjørndal L, Reit C, Bruun G, Markvart M, Kjældgaard Näsman P, Thordrup Dige I, Nyvad B, Fransson H, Lager A, Ericson D, Petersson K, Olsson J, Santimano EM, Wennström Winkel Gluud C. Treatment of deep caries lesions in adults: randomized clinical trials comparing stepwise vs. direct complete excavation, and pulp capping partial pulpotomy. Eur J Oral Sci 2010; 118: 290–297 . © 2010 The Authors. Journal compilation Less invasive excavation methods have been suggested for lesions. We tested the...
Deep caries presents a dilemma in terms of which treatment that will render an optimal prognosis by maintaining pulp vitality with absence apical pathology. Previously, 2 randomized clinical trials were performed testing the short-term effects stepwise carious tissue removal versus nonselective to hard dentin or without exposure. The aim this article was report 5-y outcome on these previously treated patients having radiographically well-defined lesions extending into pulpal quarter but...
Markvart M, Darvann TA, Larsen P, Dalstra Kreiborg S, Bjørndal L. Micro‐CT analyses of apical enlargement and molar root canal complexity. International Endodontic Journal , 45 273–281, 2012. Abstract Aim To compare the effectiveness two rotary hybrid instrumentation techniques with focus on in teeth to quantify visualize spatial details efficacy canals different Methodology Maxillary mandibular were scanned using X‐ray microcomputed tomography. Root prepared either a GT/Profile protocol or...
IntroductionThe aims were to investigate 1) the frequency of nonsurgical retreatment, root-end surgery, extraction, and further restorative treatment during a follow-up 10 11 years after root filling compare frequencies according tooth group type coronal restoration, 2) timing extraction.MethodsData collected from Swedish Social Insurance Agency's register. A search for codes identified teeth filled in 2009 restoration (direct, indirect, unspecified) registered within 6 months filling. The...
ABSTRACT Dental pain is common, and many patients use analgesics to alleviate the pain. Analgesics are readily accessible, overdosing may lead severe complications. This study explores extent of analgesic in with dental Data were collected from two emergency clinics Copenhagen, Denmark, via questionnaires interviews 180 patients. Results showed that 82.8% ( n = 149) had taken at least one type analgesic, 9% 15) exceeded recommended maximum dosage. Of all pain, 75.6% 136) used paracetamol,...
Recent studies have indicated that cerebral abscess (CA) patients with odontogenic origin are on the rise. However, CA often poorly characterized and an unknown etiologic background. The purpose of this study is to identify characterize may based microbiologic, radiographic, and/or clinical findings.This a population-based cohort analyzing retrospective prospective data from patients. Radiographic examinations panoramic radiographs (PRs) or computed tomography (CT) scans were conducted....
Abstract Background Evidence suggests a bidirectional relationship between oral health status and type 2 diabetes (T2D) in adults. Studies on associations childhood T2D adulthood are lacking. Methods This is nationwide Danish registry-based cohort study of individuals born 1963 1972, having at least one registration the National Child Odontology Registry 1972 1987 (n = 627,758). Follow-up lasted from 1995 to 2018. Main exposure variables were highest achieved levels dental caries gingivitis...
Objective: The aim of this study was to compare the needle and irrigant penetration depth a newly developed multi-vented polymer (30G), with three established designs – an open-ended metal side-vented notched (27G) used as reference control. effect manual dynamic activation (MDA) also measured. null hypotheses were that would be same regardless tip, addition MDA make no difference in terms penetration. Materials methods: A total 120 mesial roots from mandibular molars instrumented size...
The aim of this study was to re-assess the adoption certain endodontic technology and central treatment principles root canal treatments as advocated by guidelines presented European Society Endodontology.The questionnaire included same questions in 2003 2013. general dental practitioners (GDPs) anonymously reported how frequent ('often', 'occasionally', 'never') they used adhered principles. statistical analyses were performed using Chi-squared test Goodman-Kruskal's γ-coefficient an...
Frequent intake of free sugars is a major risk factor for dental caries, but the immediate influence sugar on supragingival microbiota remains unknown. We aim to characterize effect 14 days rinsing microbiota. Forty orally and systemically healthy participants rinsed their mouth with 10% sucrose solution, 6–8 times day, days, followed by without stress. Supragingival plaque samples were collected at baseline, after 14, 28 days. The was analyzed using 16S rDNA sequencing. Taxonomic...
Background Gingivitis in response to biofilm formation may exhibit different trajectories. The purposes of the present study were characterize composition supragingival microbiota and salivary cytokine protein levels healthy individuals with gingivitis patterns, test hypothesis that manifestations associate specific profiles terms microbiota, cytokines, proteins.
Background Streptococcus species are predominant members of the oral microbiota in both health and diseased conditions. The purpose present study was to explore if different ecological characteristics, such as oxygen availability presence periodontitis, associates with transcriptional activity genus Streptococcus. We tested hypothesis that genetically closely related express activities samples collected from environments critically conditions determined by site inflammatory status. Methods...
To investigate the effect of daily use a lozenge containing arginine and probiotics for 10-12 months on caries increment, gingivitis- plaque occurrence in children aged 5-9 years.
Abstract The overuse of antibiotics is accelerating the bacterial resistance, and therefore there a need to reduce amount used for treatment. Here, we demonstrate in vitro that specific wavelengths narrow range around 296 nm are able eradicate bacteria biofilm state (grown 24 hours) more effectively, than combination irradiation even better, introducing novel concept light assisted . investigated wavelength was 249 338 with an approximate step 5 nm. consists UV treatment followed by...
The objective of this study was to test the inactivation efficiency two different light-based treatments, namely ultraviolet B (UVB) and C (UVC) irradiation, on Pseudomonas aeruginosa biofilms at growth stages (24, 48, 72 h grown). In our experiments, a type AlGaN light-emitting diodes (LEDs) used deliver UV irradiation biofilms. effectiveness UVB 296 nm UVC 266 irradiations quantified by counting colony-forming units. survival less mature (24 grown) studied as function UV-radiant exposure....
Abstract Background Since 1972 The National Child Odontology Registry has collected data on the oral health of most all Danish children and adolescents. However, comprehensive information registry not previously been available, making it difficult to approach use for research purposes. Methods By combining historical documentation simple descriptive statistics we provide an overview major events in timeline discuss how they impact available data. We a broad dental variables registry,...
Disinfection routines are important in all clinical applications. The uprising problem of antibiotic resistance has driven major research efforts towards alternative disinfection approaches, involving light-based solutions. <i>Pseudomonas aeruginosa</i> (<i>P. aeruginosa</i>) is a common bacterium that can cause skin, soft tissue, lungs, kidney and urinary tract infections. Moreover, it be found on medical equipment causing often cross infections hospitals. objective this study was to test...
The present study aims to test whether probiotics protect against experimental gingivitis incited by 14 days of oral hygiene neglect and/or subsequently support the restoration homeostasis. Eighty systemically and orally healthy participants refrained from procedures for days, followed with regular procedures. Additionally, consumed either (n = 40) or placebo throughout trial. At baseline, day 14, 28, supragingival plaque score bleeding-on-probing percentage (BOP %) were registered, saliva...