A5111421171- Complement system in diseases
- COVID-19 Clinical Research Studies
- Venous Thromboembolism Diagnosis and Management
- Pharmacology and Obesity Treatment
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Diet and metabolism studies
- Atrial Fibrillation Management and Outcomes
- Bariatric Surgery and Outcomes
- Liver Disease Diagnosis and Treatment
- Long-Term Effects of COVID-19
- Erythropoietin and Anemia Treatment
- Iron Metabolism and Disorders
- Renal Transplantation Outcomes and Treatments
- Lymphoma Diagnosis and Treatment
- Renal Diseases and Glomerulopathies
- Eicosanoids and Hypertension Pharmacology
- Adipose Tissue and Metabolism
- Adipokines, Inflammation, and Metabolic Diseases
- Cultural and Mythological Studies
- Psidium guajava Extracts and Applications
- Hepatocellular Carcinoma Treatment and Prognosis
- Chronic Myeloid Leukemia Treatments
- Vaccine Coverage and Hesitancy
- Cancer Treatment and Pharmacology
- Galician and Iberian cultural studies
Hospital Universitari Sagrat Cor
2018-2023
Instituto de Neurociencia Biomédica
2023
Hebron University
2023
Hospital Universitari Sant Joan de Reus
2023
Hospital General de Catalunya
2023
Banc de Sang i Teixits
2018-2022
Universitat Internacional de Catalunya
2019-2022
Hospital de Sant Pau
2019-2020
Institut de Biologia Molecular de Barcelona
2019
Hospital Universitario Son Espases
2011-2012
Abstract Immune thrombotic thrombocytopenic purpura (iTTP) is a microangiopathy caused by anti-ADAMTS13 antibodies. Caplacizumab approved for adults with an acute episode of iTTP in conjunction plasma exchange (PEX) and immunosuppression. The objective this study was to analyze compare the safety efficacy caplacizumab vs standard care assess effect concomitant use rituximab. A retrospective from Spanish TTP Registry patients treated those who did not receive it conducted. total 155 (77...
Surgicale studied the immunogenicity of standard schedule recombinant hepatitis B vaccine (20 μmUg per dose at months 0, 1, and 6) in 21 anti-human immunodeficiency virus (HIV)-positive persons. Relatively low titers anti-HBs developed only five subjects (23.8%) 1 month after third dose; all had T4 cell counts greater than 700 cells/mm none 11 with a count below this value responded. Five 16 nonresponders to later acquired syndrome (AIDS)-related complex (two) AIDS (three), while responders...
Abstract Mantle cell lymphoma (MCL) is a mature B‐cell neoplasm with an aggressive behavior, characterized by the t(11;14)(q13;q32). Several secondary genetic abnormalities potential role in oncogenic process have been described. Studies of large MCL series using conventional cytogenetics, and correlating proliferation survival, are scarce. We selected 145 cases at diagnosis, displaying aberrant karyotype, from centers belonging to Spanish Cooperative Group for Hematological Cytogenetics....
Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is a rare disease characterized by the presence of anti-ADAMTS13 autoantibodies. Achieving accurate information on incidence and customary management important to provide appropriate diagnostic therapeutic resources. The aim this study was determine outcomes iTTP in Spain.A cross-sectional survey carried out among Spanish hospitals, focused patients ≥16 years old attended between 2015 2017, those at follow-up before that interval....
The present study was performed to analyze in detail gender- and site-related alterations the adrenergic signal transduction pathway of lipolysis fat cells isolated from subcutaneous abdominal visceral depots severely obese patients. group consisted 30 morbidly subjects (9 men 21 women) aged 41.1±1.9 years, with a body mass index (BMI) 54.7±1.7 kg/m2, who had undergone surgery. Protein levels hormone-sensitive lipase (HSL) receptors (AR), as well HSL activity lipolytic response agents were...
Hepatocellular carcinoma (HCC) is one of the most frequent types cancer worldwide, with an incidence 150 cases per 100 000 inhabitants year in Asia and Africa ∼5 Europe, North America, Australia (1). HCC can occur healthy livers, but it generally associated hepatic disease. Cirrhosis important risk factor for its development (2). Many studies have been dedicated to early detection patients chronic liver disease (CLD), based on semiannual or annual measurement serum α-fetoprotein (AFP)...
Thrombotic thrombocytopenic purpura (TTP) is a rare life-threatening thrombotic microangiopathy (TMA) characterized by the severe deficiency of ADAMTS13 activity (<10%). Rapid testing crucial for early diagnosis and optimal management TTP patients other TMAs. The objective this study was to retrospectively evaluate performance recently commercialized HemosIL Acustar® chemiluminescent immunoassay (Instrumentation Laboratory, Bedford, Massachusetts, United States) in multicentric between Spain...
Morbid obesity is a major health problem and bariatric surgery currently the most effective therapy available to induce weight loss in these patients. This report describes 1-year changes metabolic parameters, trial designed examine effects of nonsurgical approach, Intensive Life style Intervention (ILI) on morbid obesity.The primary outcome was change body weight. Patients were randomized ILI (n = 60) or conventional (COT) 46). The group received behavioural nutritional/physical activity...
Objective During the first wave of SARS-CoV-2 pandemic, management anticoagulation therapy in hospitalized patients with atrial fibrillation (AF) was simplified to low-molecular-weight heparin (LMWH) followed by oral anticoagulation, mainly owing risk drug–drug interactions. However, not all anticoagulants carry same risk. Methods Observational, retrospective, and multicenter study that consecutively included AF anticoagulated LMWH or edoxaban concomitantly empirical COVID-19 therapy....
El texto trabaja con los paralelismos entre el poema “La isla en peso” de Virgilio Piñera y cuento “El pozo” Augusto Céspedes; estos, a pesar estar contextos geográficos opuestos, comparten una desesperación similar debido al aislamiento las condiciones opresivas su entorno. Mientras que la agua rodea como condena; pozo Céspedes, soldados buscan desesperadamente un ambiente desértico. Ambos escenarios representan espacios cerrados oprimen sus habitantes, generando angustia sentido pérdida.
Abstract Objective During the first wave of SARS-CoV-2 pandemic, management anticoagulation therapy in hospitalized patients with atrial fibrillation (AF) was simplified to low-molecular-weight heparin (LMWH), mainly due risk drug-drug interactions. However, not all oral anticoagulants carry same risk. Methods Observational, retrospective, and multicenter study that consecutively included non-valvular AF who received anticoagulant treatment LMWH or edoxaban concomitantly empirical for...