A5100771771- Intracranial Aneurysms: Treatment and Complications
- Cerebrovascular and Carotid Artery Diseases
- Moyamoya disease diagnosis and treatment
- Vascular Malformations Diagnosis and Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Meningioma and schwannoma management
- Vascular Malformations and Hemangiomas
- Central Venous Catheters and Hemodialysis
- Intracerebral and Subarachnoid Hemorrhage Research
- Acute Ischemic Stroke Management
- Testicular diseases and treatments
- Neuroblastoma Research and Treatments
- Cancer, Hypoxia, and Metabolism
- Multiple Myeloma Research and Treatments
- Spinal Fractures and Fixation Techniques
- Soft tissue tumor case studies
- Neurosurgical Procedures and Complications
- Glioma Diagnosis and Treatment
- Angiogenesis and VEGF in Cancer
- Neurological Complications and Syndromes
- Bone Tumor Diagnosis and Treatments
- Management of metastatic bone disease
Shanghai Center for Brain Science and Brain-Inspired Technology
2020-2025
Fudan University
2015-2025
Shanghai Clinical Research Center
2020-2025
Huashan Hospital
2016-2025
University of Toledo
2017
Macquarie University
2014
Zhongshan Hospital
2013
<h3>BACKGROUND AND PURPOSE:</h3> Although flow diverters have been reported with favorable clinical and angiographic outcomes in various literatures, randomized trials determining their true effectiveness safety are still lack. The Parent Artery Reconstruction for Large or Giant Cerebral Aneurysms Using the Tubridge Flow Diverter (PARAT) trial was designed to evaluate efficacy of diverter treatment large giant aneurysms comparison Enterprise stent-assisted coiling. <h3>MATERIALS...
Background and Purpose- High-resolution vessel wall magnetic resonance imaging is a promising technique for assessing structures of unruptured intracranial aneurysms (UIAs). However, the relationship between aneurysmal high-resolution features their histopathologic mechanism remains poorly understood. Methods- From February 2016 to 2018, total 19 men 28 women with 54 UIAs treated surgically were prospectively enrolled. The intraoperative observed gross pathology was compared enhancement on...
Object The outcome of patients with hemorrhagic moyamoya disease (MMD) after cerebral revascularization is uncertain. purpose this study was to delineate the efficacy surgical method in treatment MMD. Methods Between January 2007 and August 2011, a consecutive cohort 113 MMD enrolled into prospective single-center study. combined direct indirect bypass. cumulative probability primary end point (all stroke deaths from surgery through 30 days ipsilateral recurrent hemorrhage afterward)...
Background and purpose The relationship between dense packing incidence of angiographic recurrence after endovascular treatment intracranial aneurysms has been shown but remains controversial. We retrospectively analyzed treated with detachable coils to determine the relation aneurysm volume, packing, recurrence. Methods reviewed 221 in 199 patients who underwent coiling using from November 2009 December 2011. Aneurysm volumes were determined three-dimensional images obtained rotational...
Because of the diversity aneurysm morphology, complicated arterial anatomy and hemodynamic characteristics, tailored surgical treatments are required for cases individual complex middle cerebral artery (MCA) aneurysms.During an 8-year period, 59 MCA aneurysms in 58 patients were treated microsurgically our department. Complex defined as having large (10-24 mm diameter) or giant (diameter ≥ 25 mm) size non-saccular morphology (fusiform, dissecting serpentine).Direct clipping aneurysmal necks...
Intracranial aneurysms are increasingly treated with endovascular treatment. Based on our observation that cerebral complications associated this treatment, we predict the number of intraprocedural will rise as a result trend.Between January 2007 and December 2013, 1739 patients underwent 1764 detachable coil embolizations to treat intracranial (637 ruptured 1127 unruptured). We reviewed their records images evaluate periprocedural related morbidity mortality.61 occurred during embolization...
Objectives The aim of the present study was to identify image-based morphological parameters and anatomical locations associated with intracranial aneurysm (IA) rupture. Methods Nine location were evaluated in 150 patients saccular IAs (82 unruptured, 68 ruptured) using three-dimensional geometry. Aneurysm including size, aspect ratio, size height–width flow angle, inclination parent artery vessel shape explored a correlation These factors analyzed two-tailed independent Student t test or χ...
An increasing number of unruptured intracranial aneurysms (UIAs) has been discovered in elderly patients recent years, but the optimal treatment strategy for these remains controversial. We report our six-year experience treating UIAs (≥ 70 years old). A retrospective review was conducted who harbored treated by conservative observation, microsurgical clipping, or endovascular coiling between January 2009 and December 2014. The patients’ clinical imaging information recorded. Treating...
Background: Dural arteriovenous fistula (DAVF) at the craniocervical junction is an unusual condition with alternative presentations and a rare cause of intracranial subarachnoid hemorrhage (SAH). We performed retrospective, angiographic study six consecutive patients to assess relation between symptom venous drainage predict risk for SAH. Methods: There were three females males; ages ranged 37 64 mean 52.5. Among them, four had SAH two pain. Diagnosis DVAF was based on CTA, MRA angiograph....
Background Surgical treatment of posterior inferior cerebellar artery (PICA) aneurysms is challenging because many are nonsaccular and atherosclerotic. We report our tailored approach to PICA aneurysms, which based on angioarchitecture supplemented by high-resolution vessel wall MRI (HR-VW MRI) findings. Methods From March 2010 September 2020, 27 patients with 29 underwent surgical in institution. Since October 2016, HR-VW has been used for aneurysmal assessment. Clinical characteristics,...
Background Scalp arteriovenous malformations (AVM) are rare vascular reported only in small case series. AVMs usually present with symptoms, including headache, tinnitus, epilepsy, cerebral ischemia, and necrosis of the scalp, which can cause functional, cosmetic, psychological problems. There many difficulties treatment scalp AVM because its complex characteristics anatomy, non-uniform structure, intracranial-extracranial anastomosis. Case description To illustrate endovascular via direct...
Nontraumatic spontaneous subarachnoid hemorrhage (SAH) is associated with a high mortality. This study was conducted to investigate the epidemiological features of nontraumatic SAH in China.From January 2006 December 2008, clinical data patients from 32 major neurosurgical centers China were evaluated. Emergent digital subtraction angiography (DSA) performed for diagnosis sources acute stage (≤3 days). The results and complications emergent DSA analyzed. Repeated or computed tomography (CTA)...
Abstract The metallic stent has been widely used in endovascular treatment of intracranial aneurysms and arterial stenosis. Endothelialization at the neck aneurysm or stenotic lesion after deployment plays a pivotal role preventing recurrence, as well local thrombus formation restenosis. To deliver autologous endothelial cells to promote endothelialization on luminal wall parent artery, we established an cell‐seeded device. Endothelial were isolated from canine jugular vein identified by...