A5088491866- Pregnancy and preeclampsia studies
- MicroRNA in disease regulation
- Adipose Tissue and Metabolism
- Cancer-related molecular mechanisms research
- Birth, Development, and Health
- Mitochondrial Function and Pathology
- Air Quality and Health Impacts
- Neonatal Respiratory Health Research
- Gestational Diabetes Research and Management
- RNA modifications and cancer
- Adipokines, Inflammation, and Metabolic Diseases
- Neonatal and fetal brain pathology
- Metabolism, Diabetes, and Cancer
- Energy and Environment Impacts
- Climate Change and Health Impacts
- Land Use and Ecosystem Services
- Anesthesia and Neurotoxicity Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Plant Water Relations and Carbon Dynamics
- Gut microbiota and health
- ATP Synthase and ATPases Research
- Circular RNAs in diseases
- Folate and B Vitamins Research
- Ferroptosis and cancer prognosis
- Neuroscience of respiration and sleep
Ministry of Ecology and Environment
2014-2025
Nanjing Institute of Environmental Sciences
2014-2025
Peking Union Medical College Hospital
2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2025
Tianjin Medical University
2025
Gansu Provincial Maternal and Child Health Hospital
2015-2024
Shaoxing People's Hospital
2023-2024
Nanjing Medical University
2008-2024
Nanjing Drum Tower Hospital
2023-2024
Shandong University
2008-2024
Problem China continues to face challenges in eliminating mother-to-child transmission of human immunodeficiency virus (HIV), syphilis and hepatitis B (HBV).Approach In 2010, a programme that integrated standardized prevention (PMTCT) efforts for HIV, HBV was implemented 1156 counties.At participating antenatal care clinics, pregnant women were offered all three tests concurrently free charge.Further interventions such as treatment, prophylaxis testing mothers their children provided HIV...
What is the current status of assisted reproductive technology (ART) service availability, efficacy and safety in mainland China?In this first national report on ART China, data treatment numbers, outcomes complications 2016 are provided analyzed, respectively.National Service Provision Surveys conducted China regularly. Data were manuscript was written by team members from National Center for Women Children's Health, CDC Department Children Health Commission People's Republic China.A...
To evaluate the independent and joint effects of maternal pre-pregnancy BMI gestational weight gain (GWG) on risk preeclampsia its subtypes. A birth cohort study was conducted from 2010 to 2012 in Lanzhou, China. Three hundred fourty seven pregnant women with 9516 normotensive at Gansu Provincial Maternity Child Care Hospital were included present study. Unconditional logistic regression models used associations between BMI, GWG, Compared normal those who overweight/obese had an increased...
Spinal cord injury (SCI) represents a relatively common type of motor system trauma. While the SCI patient will experience varying degrees paraplegia and quadriplegia, which severely affects their quality life, heavy burden is also placed on family society as whole. The exact pathogenic mechanisms underlying this condition remain unknown no specific treatments are currently available. Findings from recent studies have shown that mesenchymal stem cells (MSCs), derived extracellular vesicles...
Studies investigating the relationship between maternal passive smoking and risk of preterm birth have reached inconsistent conclusions. A cohort study that included 10,095 nonsmoking women who delivered a singleton live was carried out in Lanzhou, China, 2010 2012. Exposure to during pregnancy associated with an increased very (<32 completed weeks gestation; odds ratio = 1.98, 95% confidence interval: 1.41, 2.76) but not moderate (32–36 0.98, 0.81, 1.19). Risk duration exposure (P for trend...
Preterm neonates undergo many painful procedures as part of their standard care in the neonatal intensive unit. However, pain treatment is inadequate these routine procedures. In present study, we investigated impact and mechanism combined music touch intervention (CMT) on response premature infants. Sixty-two preterm (gestational age <37 weeks) were randomly assigned to either experimental or control group. Infants group underwent with CMT, those without CMT. Blood samples collected from...
Changes in land use can cause significant changes the ecosystem structure and process variation of services. This study presents a detailed spatial, quantitative assessment value services based on change national nature reserves Ningxia autonomous region China. We used areas types calculated from remote sensing data adjusted coefficients to assess for years 2000, 2005, 2010, analyzing fluctuations valuation response change. With increases forest water bodies, increased 182.3×107 223.8×107...
Background It has been reported that folic acid supplementation before and/or during pregnancy could reduce the risk of congenital heart defects (CHDs). However, results from limited epidemiologic studies have inconclusive. We investigated associations between maternal supplementation, dietary folate intake, and CHDs. Methods A birth cohort study was conducted in 2010–2012 at Gansu Provincial Maternity & Child Care Hospital Lanzhou, China. After exclusion stillbirths multiple births, a total...
Purpose: Spinal cord injury (SCI) is a relatively common, devastating traumatic condition resulting in permanent disability. In this study, the use of exosomes derived from bone mesenchymal stem cells (BMSCs-Exo) as cell-free therapy for treatment SCI rats was investigated to gain insights into their mechanisms action. Methods: Rats were randomly divided three groups, Sham (treated with PBS), (SCI + PBS) and Exo BMSCs-Exo). Changes complement system between groups assessed proteomics. The...
Growing evidence has shown that gut microbiome composition is associated with breast cancer (BC), but the causality remains unknown. We aimed to investigate link between BC prognosis and at various oestrogen receptor (ER) statuses.We performed a genome-wide association study (GWAS) analyse of patients, dataset for which was collected by Breast Cancer Association Consortium (BCAC). The analysis executed mainly via inverse variance weighting (IVW); Mendelian randomization (MR) results were...
Human amniotic membranes (hAMs) are widely used as wound management biomaterials, especially grafts for corneal reconstruction due to the structure of extracellular matrix and excellent biological properties. However, their fragile nature rapid degradation rate hinder widespread clinical use. In this work, we engineered a novel self-powered electronic dress (E-dress), combining beneficial properties an membrane flexible electrical electrode enhance healing. The E-dress displayed sustained...
Congenital heart defects are the most prevalent type of birth defects. The association air pollution with congenital is not well understood. We investigated a cohort 8,969 singleton live births in Lanzhou, China during 2010-2012. Using inverse distance weighting, maternal exposures to particulate matter diameter ≤10μm (PM10), nitrogen dioxide (NO2), and sulfur (SO2) were estimated as combination monitoring station levels for time spent at home work location. used logistic regression estimate...
The aim of this study was to investigate the epidemiological characteristics and adverse pregnancy outcomes pregnant women with syphilis infection in China.Data were from China's Information System Prevention Mother-to-Child Transmission Syphilis Management. Women who registered system delivered 2013 included analysis.A total 15884 China 2013. 79.1% infected attended antenatal care at or before 37 gestational weeks; however, 55.4% received no treatment initiated after weeks. 14.0% suffered...
As a critical component of the geographical divide between northern and southern regions China, ecological stability Qinling region has profound implications for balance within China across East Asia. However, degradation risk areas remain unclear, there are gaps in delineation key protection areas. This study examines improvement decline from 2000 to 2023 terms ecosystem patterns, quality, functions. Moreover, function zones were identified, future development paths proposed region. The...
Artificial selection has greatly shaped crop agronomic traits; however, the mechanistic basis of immunity remained elusive. This study identifies a new rice NLR XA48 and its downstream transcription factor OsVOZ1, which confer bacterial blight resistance. perceives an ancient pathogen effector, XopG, to activates effector-triggered (ETI). The XA48-OsVOZ1 module undergone subspecies-specific selection. Xa48 is retained in indica but functionally lost japonica rice. OsVOZ1 also diverged into...
Diabetic Cardiomyopathy (DCM) is a heart condition that arises specifically from diabetes mellitus, characterized by cardiac dysfunction in the absence of coronary artery disease or hypertension. The prevalence DCM rising tandem with global increase diabetes, necessitating development early diagnostic markers and therapeutic targets. This study integrates bioinformatics analysis experimental validation to identify potential biomarkers for DCM. We performed gene expression data mining Gene...
Early studies have suggested that biomass cooking fuels were associated with increased risk of low birth weight (LBW). However it is unclear if this reduced was due to prematurity or intrauterine growth restriction (IUGR).In order understand the relationship between various and LBW small for gestational age (SGA), we analyzed data from a cohort study conducted in Lanzhou, China which included 9,895 singleton live births.Compared mothers using gas as fuel, significant reductions observed coal...