A5100710359- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- Syphilis Diagnosis and Treatment
- Adolescent Sexual and Reproductive Health
- Gestational Diabetes Research and Management
- Synthesis and Characterization of Pyrroles
- Sex work and related issues
- Innovations in Medical Education
- HIV, TB, and STIs Epidemiology
- Mathematical and Theoretical Epidemiology and Ecology Models
- HIV-related health complications and treatments
- Pregnancy and preeclampsia studies
- Simulation-Based Education in Healthcare
- Pregnancy-related medical research
- Organic Chemistry Cycloaddition Reactions
- Prenatal Screening and Diagnostics
- Porphyrin and Phthalocyanine Chemistry
- Evolution and Genetic Dynamics
- Asthma and respiratory diseases
- Esophageal Cancer Research and Treatment
- Neurological Disease Mechanisms and Treatments
- Job Satisfaction and Organizational Behavior
- Medicinal Plant Pharmacodynamics Research
- Global Maternal and Child Health
- Cardiovascular Health and Risk Factors
National Center for Women and Children’s Health, China CDC
2015-2024
Chinese University of Hong Kong
2024
Anhui Medical University
2009-2024
Wuhan Donghu University
2020-2024
Wuhan University
2009-2024
Anhui University of Traditional Chinese Medicine
2024
First Affiliated Hospital of Anhui Medical University
2009-2024
Shanghai Normal University
2024
Dalian Polytechnic University
2024
Shanxi Medical University
2023
Problem China continues to face challenges in eliminating mother-to-child transmission of human immunodeficiency virus (HIV), syphilis and hepatitis B (HBV).Approach In 2010, a programme that integrated standardized prevention (PMTCT) efforts for HIV, HBV was implemented 1156 counties.At participating antenatal care clinics, pregnant women were offered all three tests concurrently free charge.Further interventions such as treatment, prophylaxis testing mothers their children provided HIV...
Abstract Background Virtual simulation and face-to-face are effective for clinical judgment training. Rare studies have tried to improve ability by applying virtual together. This study aimed evaluate the effect of an integrated non-immersive high-fidelity program on enhancing nursing students’ understanding experiences combined simulation. Methods A sequential exploratory mixed-methods was conducted in a center university Central China. Third-year students ( n = 122) taking training ICUs...
The aim of this study was to investigate the epidemiological characteristics and adverse pregnancy outcomes pregnant women with syphilis infection in China.Data were from China's Information System Prevention Mother-to-Child Transmission Syphilis Management. Women who registered system delivered 2013 included analysis.A total 15884 China 2013. 79.1% infected attended antenatal care at or before 37 gestational weeks; however, 55.4% received no treatment initiated after weeks. 14.0% suffered...
Doxorubicin (DOX), which is widely used for the treatment of cancer, induces cardiomyopathy associated with NADPH oxidase-derived reactive oxygen species. GSK2795039 a novel small molecular oxidase 2 (Nox2) inhibitor. In this study, we investigated whether prevents receptor-interacting protein kinase 1 (RIP1)-RIP3-mixed lineage domain-like (MLKL)-mediated cardiomyocyte necroptosis in DOX-induced heart failure through inhibition. Eight-week old mice were randomly divided into 4 groups:...
Early screening for syphilis among pregnant women and the effective treatment of maternal is fundamental to prevent congenital (CS).We obtained data from Shenzhen Program Prevention CS (SPPCS) estimated incidence rates infants born syphilis-seropositive treated with different regimens or untreated syphilis.A total 4746 matched cases mothers their were included analyses, 162 diagnosed CS, providing an overall 3.41% (95% confidence interval [CI], 2.91%-3.98%). Among who had adequately before...
In China, recent rises in syphilis and HIV cases have increased the focus on preventing mother-to-child transmission of these infections. We assess health economic outcomes different strategies prenatal screening from local department's perspective.A Markov cohort decision analysis model was used to estimate pregnancy using disease prevalence cost data sources and, if unavailable, published literature. Adverse included induced abortion, stillbirth, low birth weight, neonatal death,...
Objective: Gestational diabetes mellitus (GDM) is a condition of glucose intolerance, which may be accompanied with inflammation. The levels hematological parameters during pregnancy can reflect inflammatory conditions in pregnant women. This study aims to describe the dynamic change blood cell from first trimester (6– 12 weeks gestation) second (24– 28 and investigate associations these biomarkers risk GDM. Methods: was prospective double-center conducted Beijing, China (clinical trial...
Objective: To investigate the ability of homeostasis model assessment insulin resistance (HOMA-IR) in early pregnancy for predicting gestational diabetes mellitus (GDM) Chinese women with different first-trimester body mass index (FT-BMI) values. Methods: Baseline characteristics and laboratory tests were collected at first prenatal visit (6−12 weeks gestation). GDM was diagnosed by a 75 g oral glucose tolerance test (OGTT) 24−28 gestation. Partial correlation analysis binary logistic...
Abstract Pregnant women infected with HCV should be given attention due to their special physiological stage and the effect on offspring health. To examine prevalence of infection among pregnant in part China explore relevant factors during pregnancy, a cross-sectional study was conducted four maternal children health care institutions (MCHC) Guangdong, Hunan Chongqing. who were delivered, induced or spontaneous abortion included information collected through Hospital Information System....
To study the protective mechanism of nicorandil on myocardial ischemia-reperfusion injury.Fifty rats were randomly divided into five groups, four which operated to produce ischemia-reperfusion. Nicorandil (5 mg/kg) was administrated by intravenous injection three groups. The ultrastructure observed electron microscope. expression levels antiapoptotic protein Bcl-2 and pro-apoptotic Bax detected immunohistochemical staining with rhodamine 123. mitochondrial membrane potential...
Macrophage phenotype and function varies according to their polarized state, which in turn is dependent on microenvironmental stimuli. Under normal physiological conditions, lung interstitial macrophages that express interleukin (IL)-10 are considered serve regulatory roles the prevention of allergic reactions airways. However, phenotypic profile during pathophysiology asthma remains unknown. In current study, characteristics were investigated an ovalbumin (OVA)-induced mouse model asthma....
Dysfunction of cardiac autonomic nerve system is considered as one risk factors for coronary atherosclerotic heart disease. Heart rate variability (HRV) has been used to study the correlation between damage artery and dysfunction nervous system. We hypothesize by HRV among subjects with stable angina.A 236 who diagnosed angina pectoris elective angiography, were divided into two groups Gensini score (GS):GS≤32 (GS1) GS2>32 (GS2). Subgroups based on location stenosis lesions number 86...
Allergic diseases are highly prevalent in the women of childbearing age. As we know, immune system could change when pregnancy, which may affect course allergic diseases. Meanwhile, they also can and outcome pregnancy. The data on incidence allergies during pregnancy is lacking conducting clinical trials pregnant was limited, therefore, observed a prebirth cohort to supplement relevant strengthen concerned research conductions.
Abstract Smoking by psychiatric patients remains prevalent. The purpose of this cross‐sectional study was to understand the influence self‐efficacy and its correlates among nurses when providing smoking‐cessation services (SCS). A convenience sample 193 from institutions obtained. Surveys were conducted using self‐report measures regarding SCS provided nurses. survey questions focused on self‐efficacy, attitude, practical experience, smoke‐free policies, their implementation in workplace....
Previous studies have suggested that adequate myocardial reperfusion after percutaneous coronary intervention (PCI) can improve the inhomogeneity of repolarization. However, it remains unclear whether no-reflow (NR) following emergency PCI involves disadvantages related to ventricular repolarization indices. The present study aimed determine effect NR on QT dispersion (QTd) in patients with ST-segment elevation infarction (STEMI) and evaluate prognostic value relative reduction QTd...
Gestational diabetes mellitus (GDM) is one of the most common medical complications pregnancy, which increases risk other pregnant and adverse perinatal outcomes. Thyroid dysfunction closely with mellitus. However, relationship between euthyroid function in early pregnancy GDM still controversial.
Abstract This study investigates the improvement of prevention mother-to-child transmission (PMTCT) Human Immunodeficiency Virus (HIV) in China during 2004–2011. A clinic-based prospective was conducted among HIV-positive pregnant women and their children eight counties across China. Associated factors were analyzed using regression analysis. total 1,387 HIV+ 1,377 HIV-exposed infants enrolled. The proportion who received HIV testing increased significantly from 45.1% to 98.9% Among whom,...