A5044362390- Analytical chemistry methods development
- Ion-surface interactions and analysis
- Radioactive element chemistry and processing
- Scientific Measurement and Uncertainty Evaluation
- Nuclear Physics and Applications
- Mass Spectrometry Techniques and Applications
- Particle accelerators and beam dynamics
- Laser-induced spectroscopy and plasma
- Extraction and Separation Processes
- Analytical Chemistry and Sensors
- Radioactive contamination and transfer
- Isotope Analysis in Ecology
- Plasma Diagnostics and Applications
- Bacterial Genetics and Biotechnology
- Particle Detector Development and Performance
- Electron and X-Ray Spectroscopy Techniques
- X-ray Spectroscopy and Fluorescence Analysis
- Particle Accelerators and Free-Electron Lasers
- Radioactive Decay and Measurement Techniques
- Congenital heart defects research
- Superconducting Materials and Applications
- Atomic and Molecular Physics
- Advancements in Battery Materials
- Radioactivity and Radon Measurements
- Bacteriophages and microbial interactions
Federal Institute For Materials Research and Testing
2013-2025
Universidade Federal da Fronteira Sul
2024
Universidade Federal do Pampa
2024
Pontifícia Universidade Católica do Rio Grande do Sul
2024
Universidade Federal do Rio Grande do Sul
2024
Helmholtz Centre for Environmental Research
2016
European Commission
2013
Max Delbrück Center
2010
Charité - Universitätsmedizin Berlin
2009
Martin Luther University Halle-Wittenberg
2005-2008
<h3>Background</h3> Ostium secundum atrial septal defects (ASDII) account for approximately 10% of all congenital heart (CHD), and mutations in cardiac transcription factors, including <i>TBX20</i>, were identified as an underlying cause ASDII. However, very little is known about disease penetrance families functional consequences inherited TBX20 mutations. <h3>Methods</h3> The coding region <i>TBX20</i> was directly sequenced 170 ASDII patients. Functional one novel mutation investigated by...
The analytical potential of a nanosecond laser ablation inductively coupled plasma mass spectrometer system, equipped with an ultra-fast wash-out chamber, is critically investigated for fast and highly spatially resolved (∼μm) qualitative elemental distribution within single cells.
Abstract This work presents the development and certification of world’s first certified reference material (CRM), BAM-S014, for a lithium nickel manganese cobalt oxide (LiNi 0.33 Mn Co O 2 or Li-NMC 111) cathode material—an integral component in high-energy-density lithium-ion batteries that power electric vehicles (EVs), portable electronics, stationary energy storage systems. By providing mass fractions 11 elements, this CRM addresses critical need accurate traceable elemental analysis,...
The twin-arginine translocation (Tat) system is a protein that adapted to the of folded proteins across biological membranes. An understanding folding requirements for Tat substrates fundamental importance elucidation transport mechanism. We now demonstrate first time fully unstructured proteins, using signal sequence fusions naturally unfolded FG repeats from yeast Nsp1p nuclear pore protein. becomes less efficient with increasing size, consistent only single interaction between and...
The twin-arginine translocation (Tat) system of bacteria and plant plastids serves to translocate folded proteins across energized biological membranes. In Escherichia coli, the three components TatA, TatB, TatC mediate this membrane passage. Here we demonstrate that TatA can assemble form clusters tube-like structures in vivo. While presence is essential for their formation, TatB not required. tubes have uniform outer inner diameters about 11.5 nm 6.7 nm, respectively. They align a...
Experiments with SF<sub>6</sub>, NF<sub>3</sub>, CF<sub>4</sub>and H<sub>2</sub>as new modifier gases for the matrix studied were performed. Pre-treatment steps of sub-samples (<italic>e.g.</italic>, roasting) can now be omitted; scope application was enlarged to Au and hydride forming elements (such as Se, Te).
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The challenge of performing a time-resolved comprehensive analysis molecular systems has led to the quest optimize extraction methods. When size biological sample is limited, there demand for simultaneous molecules representing four areas "omics": genomics, transcriptomics, proteomics, and metabolomics. Here we optimized protocol DNA, RNA, proteins, metabolites compared it with two existing protocols. Our optimization comprised addition methanol/chloroform metabolite purification before...
Absolute, total, single- and multiple-electron-loss cross sections are measured for $1.4\text{\ensuremath{-}}\mathrm{MeV}∕\mathrm{u}\phantom{\rule{0.3em}{0ex}}{\mathrm{U}}^{4,6,10+}$ ions colliding with neon argon atoms nitrogen molecules. It is found that the all have same dependence on number of electrons lost multiplying by initial in $6s$, $6p$, $5f$ shells yields good agreement between different projectiles. By combining present data previous measurements made at velocity, it shown...
Inspired by the globule arc technique a new electrothermal vaporization inductively coupled plasma optical emission spectrometry (ETV-ICP OES) method was developed for analysis of high-purity copper materials. The performance investigated analytes Ag, Al, As, Bi, Cd, Co, Cr, Fe, Mg, Mn, Ni, P, Pb, S, Sb, Se, Si, Sn, Te, Ti, Zn and Zr. ETV parameters were optimized regarding release analytes, transport efficiency quality analytical results in terms precision, trueness power detection....
This study introduces an improved spectrometric method with enhanced precision to determine isotope ratios in geological samples without chromatographic separation. Firstly, the improvement is achieved by increasing spectral resolution of spectrometer applied well-known high-resolution continuum source atomic absorption spectrometry (HR-CS-AAS). The resulting resolving power and linear dispersion upgraded setup, which denoted following as HR + CS-AAS, well adapted line widths Li components...
How a plastic duck fits in the oven?
An alternative method for lithium isotope amount ratio analysis based on a combination of high-resolution atomic absorption spectrometry and spectral data by machine learning (ML) is proposed herein. It the well-known shift approximately 15 pm electronic transition 22P←22S at around wavelength 670.8 nm, which can be measured state-of-the-art continuum source graphite furnace spectrometry. For analysis, scalable tree boosting ML algorithm (XGBoost) was employed calibrated using set samples...
During its 25 years of existence, the Inorganic Analysis Working Group Consultative Committee for Amount Substance: Metrology in Chemistry and Biology (CCQM IAWG) has achieved much establishing comparability measurement results. Impressive work been done on comparison exercises related to real-world problems fields such as ecology, food, or health. In more recent attempts, measurements comparisons were focused calibration solutions which are basis most inorganic chemical measurements. This...
Absolute total-, single-, and multiple-electron-loss cross sections are measured for $({\mathrm{Ar}}^{+}\ensuremath{-},$ ${\mathrm{Ar}}^{2+}\ensuremath{-},$ ${\mathrm{Xe}}^{3+})\ensuremath{-}(\mathrm{Ne},$ ${\mathrm{N}}_{2},$ Ar) collisions at 0.74 1.4 MeV/u. In addition, a many-body classical trajectory Monte Carlo model was used to calculate total- ${\mathrm{Ar}}^{+}$ impact. For ${\mathrm{N}}_{2}$ Ar targets, excellent agreement between the calculated is found; Ne target experimental data...
The performance of glow discharge mass spectrometry (GD-MS) is investigated for the accurate quantification metallic impurities and oxygen in solid samples using fast flow source GD-MS instrument ELEMENT GD.