A5032852853- Cardiovascular Health and Risk Factors
- Oral microbiology and periodontitis research
- Dental Health and Care Utilization
- Blood Pressure and Hypertension Studies
- Hormonal and reproductive studies
- Criminal Justice and Corrections Analysis
- Acute Ischemic Stroke Management
- Homelessness and Social Issues
- Oral Health Pathology and Treatment
- Parathyroid Disorders and Treatments
- Food Security and Health in Diverse Populations
- Folate and B Vitamins Research
- Cardiac Health and Mental Health
- Health disparities and outcomes
- Adipokines, Inflammation, and Metabolic Diseases
- Cardiovascular Function and Risk Factors
- COVID-19 and healthcare impacts
- Cardiovascular Disease and Adiposity
- Racial and Ethnic Identity Research
- COVID-19 and Mental Health
- Biomarkers in Disease Mechanisms
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Dental Radiography and Imaging
- Apelin-related biomedical research
- Child Abuse and Trauma
Harvard University
2014-2025
Brigham and Women's Hospital
2015-2024
Boston Children's Hospital
2022
Lemuel Shattuck Hospital
2022
Hospital Universitario Fundación Jiménez Díaz
2012-2022
Women's Health Research Institute
2018
Michigan State University
2018
Brown University
2018
University of Tasmania
2018
Yale University
2018
Author(s): Writing Group Members; Mozaffarian, Dariush; Benjamin, Emelia J; Go, Alan S; Arnett, Donna K; Blaha, Michael Cushman, Mary; Das, Sandeep R; de Ferranti, Sarah; Despres, Jean-Pierre; Fullerton, Heather Howard, Virginia Huffman, Mark D; Isasi, Carmen Jimenez, Monik C; Judd, Suzanne E; Kissela, Brett M; Lichtman, Judith H; Lisabeth, Lynda Liu, Simin; Mackey, Rachel Magid, David McGuire, Darren Mohler, Emile Moy, Claudia Muntner, Paul; Mussolino, Nasir, Khurram; Neumar, Robert W;...
The question of the importance keratinized mucosa around dental implants for prevention peri-implant disease could not be answered in relevant literature so far.To investigate influence on long-term soft-tissue health and stability over a period 5 years.A total 386 mandibular were placed 73 completely edentulous patients, subsequently restored with fixed full-arch prostheses. At prosthesis delivery (baseline) after 3, 6, 12, 18, 24, 36, 48 60 months, modified plaque index (mPlI), sulcus...
Background— Several epidemiological studies have suggested periodontitis as a risk factor for coronary heart disease (CHD), but results been inconsistent. Methods and Results— We evaluated the association between clinical radiographic measures of periodontitis, edentulism, incident CHD (angina, myocardial infarction, or fatal CHD) among 1203 men in VA Normative Aging Dental Longitudinal Studies who were followed up with triennial comprehensive medical dental examinations to 35 years (median...
To identify associations between periodontitis and incidence of cerebrovascular disease.We analyzed data 1,137 dentate men in the Veterans Affairs Normative Aging Dental Longitudinal Study who were followed with triennial medical/dental exams for up to 34 years (mean, 24 years). We evaluated events consistent stroke or transient ischemic attack relation mean radiographic alveolar bone loss (a measure history) cumulative periodontal probing depth current inflammation). Cox proportional...
Vitamin D insufficiency is highly prevalent, with particular subgroups at greater risk (e.g. the elderly and those darker skin). may partly explain US racial/ethnic disparities in prevalence of periodontitis tooth loss. We evaluated association between a predictor score plasma 25-hydroxyvitamin (25(OH)D) incidence loss.Detailed biennial questionnaires were collected on medical history, lifestyle practices incident The was derived from variables known to influence circulating concentrations...
This cohort study describes the COVID-19 burden among incarcerated individuals and staff in Massachusetts jails prisons assesses association of case rates with decarceration testing rates.
Background— Few prospective studies have examined quantitative cigarette consumption and smoking cessation on sudden cardiac death (SCD) risk with long-term follow-up. Methods Results— We prospectively the association between of SCD among 101 018 women participating in Nurses’ Health Study without known coronary heart disease, stroke, cancer at baseline 1980. During 30 years follow-up, we identified 351 events. Compared never smokers, current smokers had a 2.44-fold (95% CI, 1.80–3.31)...
Obesity induced inflammation may promote periodontal tissue destruction and bone resorption inducing tooth loss. We examined the association between measures of adiposity self-reported disease, using data from 36,910 healthy male participants Health Professionals Follow-Up Study (HPFS) who were free disease at baseline followed for ≤20 years (1986-2006). Self-reported height, weight, collected baseline, weight additionally on biennial follow-up questionnaires waist hip circumference in 1987....
Light-to-moderate alcohol consumption has been consistently associated with lower risk of heart disease, but data for stroke are less certain. A light-to-moderate intake suggested, the dose response among women remains uncertain and in this subgroup have sparse.A total 83 578 female participants Nurses' Health Study who were free diagnosed cardiovascular disease cancer at baseline followed-up from 1980 to 2006. Data on self-reported assessed updated approximately every 4 years, whereas...
To investigate the association between sleep disordered breathing (SDB) and severe chronic periodontitis.Cross-sectional data analysis from Hispanic Community Health Study/Study of Latinos.Community-based setting with probability sampling four urban US communities.12,469 adults aged 18-74 y.None.Severe periodontitis was defined using Centers for Disease Control Prevention/American Academy Periodontology case classification based on full-mouth periodontal assessments performed by calibrated...
Background and Purpose— Lower plasma magnesium levels may be associated with higher blood pressure endothelial dysfunction, but sparse prospective data are available for stroke. Methods— Among 32 826 participants in the Nurses’ Health Study who provided samples 1989 to 1990, incident ischemic strokes were identified confirmed by medical records through 2006. We conducted a nested case–control analysis of 459 cases, matched 1:1 controls on age, race/ethnicity, smoking status, date draw,...
Background and Purpose— Previous research suggests greater risk of coronary heart disease with lower levels the adrenal steroid dehydroepiandrosterone sulfate (DHEAS). No studies have examined association between DHEAS ischemic stroke. may influence stroke through atherosclerotic-related mechanisms (endothelial function smooth muscle cell proliferation) or insulin resistance. Methods— Between 1989 1990, 32 826 women without prior in Nurses’ Health Study, an observational cohort, provided...
Background Several cross‐sectional, but few prospective, studies suggest that inflammation may be involved in the development of hypertension. We examined markers inflammation—high‐sensitivity C‐reactive protein, interleukin‐6, and soluble intercellular adhesion molecule‐1—and a marker fibrinolysis, D‐dimer, for their associations with incident hypertension Physicians' Health Study. Methods Results Baseline blood values information on hypertension‐related risk factors were collected 1982....
Racial differences in metabolomic profiles may reflect underlying social determinants of health by self-reported race and be related to racial disparities coronary heart disease (CHD) among women the United States. However, magnitude between Black White States has not been well-described. It also remains unknown whether such are CHD risk. Plasma were analyzed using liquid chromatography-tandem mass spectrometry WHI-OS (Women's Health Initiative-Observational Study; 138 696 women), WHI-HT...