The hypothalamus-pituitary-target gland axis is thought to be linked with insomnia, yet there has been a lack of further systematic studies prove this. This study included 30 patients primary insomnia (PI), depression-comorbid (DCI), and healthy controls for exploring the alterations in hypothalamus-pituitary-adrenal/thyroid axes' hormones gonadotropin-releasing hormone (GnRH). Pittsburgh Sleep Quality Index was used evaluate sleep quality all subjects. serum concentrations...

A series of 3,6-diaryl-2,5-dihydroxybenzoquinones were synthesized and evaluated for their abilities to selectively activate human insulin receptor tyrosine kinase (IRTK). 2, 5-Dihydroxy-6-(1-methylindol-3-yl)-3-phenyl-1,4-benzoquinone (2h) was identified as a potent, highly selective, orally active small-molecule activator. It activated IRTK with an EC(50) 300 nM did not induce the activation closely related receptors (IGFIR, EGFR, PDGFR) at concentrations up 30 000 nM. Oral administration...

Purpose: Smartphone is an indispensable everyday tool for college students, while excessive usage of smartphones may lead to negative outcomes, such as academic procrastination. Previous research has suggested that smartphone addiction a predisposing factor To further understand the above relationship, structural equation model analysis was used examine mediating effects time management and learning strategic approach in association with Materials Methods: A cross-sectional study conducted...

This study explored how coach leadership behavior, achievement goal orientation, and basic psychological needs affect athlete engagement. Based on self-determination theory, this examined the influence of behavior orientation engagement, as well mediating effect needs. The utilized established scales, including Leadership Behavior Scale for Coaches-15 (LSS-15), Achievement Goal Questionnaire Sport (AGQ-S), Athlete Engagement (AEQ) Basic Psychological Needs (BPNQ). A total 351 valid...

Abstract Objective This study aimed to examine the relationship between depression and two dimensions of hope (pathways thinking agency thinking) in college students explore dynamics causal these variables. Methods A longitudinal was conducted included 381 students. Hope were measured using Snyder's State Scale Center for Epidemiological Survey Depression respectively, four times within a year (at 4‐month intervals), cross‐lagged regression analysis performed. Results The bidirectional paths...

Mesodiencephalic dopaminergic (mDA) neurons are critical for movement control and other physiological activities. However, the molecular mechanisms underlying their development poorly understood. We aimed to establish expression profiles of genes involved in this process unravel genetic programs that late mDA neurons. compared genome-wide gene developing mouse ventral mesencephalon (VM) using microarrays. identified a set show spatially temporally restricted VM an Ngn2 (neurogenin...

Isoliquiritigenin, a flavonoid found in licorice, has been considered as an antioxidive and hepato-protective agent. Recent studies have shown that possible mechanism for triptolide-induced hepatotoxicity is related to oxidative damage induced by reactive oxygen species. This study was done investigate the protection effect of isoliquiritigenin against involved. An acute liver injury model established intraperitoneal injection triptolide (1.0 mg · kg-1) mice. Different doses (12.5, 25 50...

Grit plays a critical role in the academic achievement and future career success of college students. The family environment has an important influence on development individual grit, but mechanisms linking grit are not well known. To further understand these relationships, this study sought to explore mediating basic psychological needs between parental autonomy support moderating motivation.The present model was developed according proposed hypotheses analyzed using structural equation...

This paper demonstrates the effectiveness of a diversification mechanism for building more robust multi-attention system in generic facial action analysis. While previous (e.g., visual attention and self-attention) research on expression recognition (FER) Action Unit (AU) detection have been thoroughly studied to focus "external diversification", where branches localize different areas, we delve into realm "internal diversification" explore impact diverse patterns within same Region Interest...

Only-child loss parents in China recently gained extensive attention as a newly defined social group. Resilience could be probable solution out of the psychological dilemma. Using sample 185 only-child people, this study employed latent class analysis (a) to explore whether different classes resilience identified, (b) determine socio-demographic characteristics each class, and (c) compare depression subjective well-being class. The results supported three-class solution, 'high...

This study was carried out to test the factor structure and psychometric properties of Barratt Impulsiveness Scale–Version 11 (BIS-11), its short versions (the eight-item 15-item BIS) in a sample 424 Chinese male prisoners ( M = 31.26, SD 7.43, age 18-52 years). Confirmatory analysis (CFAs) indicated that single-factor model BIS with eight items (BIS-8) three-factor 15 (BIS-15) fit data well. In addition, item response theory (IRT) approach confirmed construct for BIS-8 good discrimination,...

Since the early 1980s, one-child policy has been implemented nationwide in China. A special group called "only-child-lost family" (OCL family) emerged and become a social phenomenon that cannot be ignored. We report latent profiles of posttraumatic growth their relation to differences resilience among OCL people China.A total 222 were investigated using Posttraumatic Growth Inventory Connor-Davidson Resilience Scale. Latent profile analysis was applied explore PTG profiles. Multinomial...

There has been a growing interest in research on hope recent years. The Children's Hope Scale (CHS) is the most commonly used scale to evaluate goal-related hopeful thinking children and adolescents. Socioeconomic status (SES) strongly influences an individual's experiences from childhood throughout adult life. This study aimed measurement invariance of CHS across SES. sample consisted 1934 Chinese youths (50.4% females) with mean age 12.96 (SD = 2.686). An overall family SES score was...

Although extensive literature has addressed depression among adolescents, few studies have emphasized the classification features of depressive symptoms in adolescents. To gain insight into hierarchy and heterogeneity adolescents based on symptoms, 5086 completed Chinese version Center for Epidemiological Studies Depression Scale (CES-D). Using Latent Class Analysis (LCA), we identified different subgroups symptoms. Multivariate logistic regression analysis was implemented to examine...

To deeply explore the relationship between parental psychological control and negative risk-taking behaviors among Chinese college students mediating role of autonomy self-control, providing a reference basis for preventing intervening in students' behaviors.

The original Snyder's Dispositional Hope Scale (DHS) was applied to 224 American college students and the Chinese version 255 students. Equivalence of two DHS tested, including configural invariance, metric scalar invariance. results demonstrated that has measurement equivalence between students; is, same psychological structure measured in samples. Therefore, cross‐cultural measurements hope are valid. In addition, did not differ significantly on Agency factor whereas scored higher than...

(2021). The effect of childhood maltreatment on college students' depression symptoms: mediating role subjective well-being and the moderating MAOA gene rs6323 polymorphism. European Journal Developmental Psychology. Ahead Print.

With enactment of the universal two-child policy in China 2016, family will replace one-child as main form. In this study we examined contribution sibling relationship quality shaping mental health Chinese children a family. Parents ( N = 280) reported their children’s relationship, and firstborn’s problematic prosocial behavior, temperament. Parents’ marital satisfaction coparenting were also assessed. The results showed that after had controlled for child characteristics age, gender,...