A5100776023- Retinal Diseases and Treatments
- Glaucoma and retinal disorders
- Liver Disease Diagnosis and Treatment
- Diet, Metabolism, and Disease
- Ultrasound and Hyperthermia Applications
- Metabolomics and Mass Spectrometry Studies
- Case Reports on Hematomas
- Nitric Oxide and Endothelin Effects
- Renin-Angiotensin System Studies
- Eicosanoids and Hypertension Pharmacology
- Retinopathy of Prematurity Studies
- Retinal Development and Disorders
- Lymphoma Diagnosis and Treatment
- CAR-T cell therapy research
- Gout, Hyperuricemia, Uric Acid
- Tryptophan and brain disorders
- Lipid metabolism and disorders
- Eosinophilic Disorders and Syndromes
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Alcohol Consumption and Health Effects
- Ocular Oncology and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Retinal and Macular Surgery
- Chronic Myeloid Leukemia Treatments
- Immune Cell Function and Interaction
People 's Hospital of Jilin Province
2023-2025
Huaian First People’s Hospital
2025
Nanjing Medical University
2016-2025
Fudan University
2021-2024
Huashan Hospital
2021
Xinjiang Uygur Autonomous Region Disease Prevention and Control Center
2015
Moffitt Cancer Center
2015
Peking University
2010-2011
Tianjin First Center Hospital
2010
Peking University People's Hospital
2010
Abstract Objective This retrospective cohort study aims to evaluate and compare different postoperative pain management strategies for esophageal squamous cell carcinoma (ESCC), in order provide scientific evidence clinical practice decision-making. Methods A total of 274 ESCC patients who underwent surgery at the Affiliated Huai’an No. 1 People’s Hospital Nanjing Medical University were included study. Of these, 127 received conventional nursing decisions management, 147 “5 + nursing”...
Abstract Xuefu Zhuyu Decoction (XZD) is widely used in the treatment of cardiovascular diseases. The purpose this study was to explore pharmacological effects and molecular mechanisms XZD improving hyperlipidemia provide a theoretical framework for clinical application. In study, signaling pathways regulated by were predicted network pharmacology. Molecular docking verify affinity between components target. Furthermore, hyperlipidemic model rats constructed through feeding high‐fat diet....
Tiaogan Jiejiu Tongluo formula (TJTF) is a traditional Chinese medicine for liver disease. The purpose of this study was to explore the protective effects and mechanisms TJTF on nonalcoholic fatty disease (NAFLD) mice. A NAFLD model mice established by combination high-fat diet CCL4 then treated with TJTF. damage tissue observed through histopathology, levels AST, ALT, TG, TC, LDL-C, HDL-C in serum, as well SOD, GSH, MDA were determined using biochemistry or ELISA kit. expression proteins...
Abstract Background Diffuse large B‐cell lymphoma (DLBCL) patients refractory to rituximab‐based immunochemotherapy have a dismal prognosis. However, the definition of DLBCL remains inconsistent and no cohort study data is available from Asian countries. To validate outcomes in China, we conducted multicenter, retrospective study. Methods The REtrospective AnaLysis Treatment REspoNse (REAL‐TREND) was performed using real‐world 8 centers China. with curative intent were included REAL‐TREND...
The programmed death-ligand 1 (PD-L1) on the surface of tumor cells binds to receptor cell death protein (PD-1) effector T cells, thereby inhibiting anti-tumor immune response. Immune checkpoint blockade (ICB) therapy targeting PD-1/PD-L1 has been approved for treatment human cancers with lasting clinical benefit. However, many cancer patients did not respond anti-PD-1/PD-L1 antibody blocking or drugs PD-1/PD-L1. Recent studies have shown that response may be related PD-L1 abundance cells....
Summary Aliskiren, a direct renin inhibitor, has shown potent ability to attenuate hypertension. Our previous research found that aliskiren protected against myocardial ischaemia‐reperfusion (I/R) injury and enhanced phosphorylation of endothelial nitric oxide synthase (eNOS) in spontaneously hypertensive rats. However, whether the cardioprotective effect I/R was eNOS‐dependent is unknown. In present study, 12‐week‐old male eNOS knockout (eNOS −/− ) wild‐type C57BL/6J mice (WT) were orally...
To study the effects of danhong huayu koufuye (DHK) on fasting blood glucose (FBG) and diabetic retinopathy (DR) in streptozotocin (STZ)-induced type 1 rats to facilitate rational usage this drug.Diabetic were induced by injection a single dose STZ intraperitoneally at 50mg/kg. Flash electroretinogram (FERG) oscillatory potentials (OPs) used measure retinal function. The microvascular perfusion ears was performed microcirculation rats. FBG, body-weight, 24-h urine volume, water intake diet...
The association between the polymorphism of SLC17A1 gene and hyperuricemia in Uyghur population Xinjiang region was explored by Chi-square test. A total 1 024 patients with 033 healthy volunteers were included.The genotype frequencies CC, CT, TT controls 24.9%, 53.14%, 21.96% 29.7%, 47.52%, 22.77%, respectively. There statistical difference rs9467596 cases controls(χ2=7.492, P=0.024). CT could increase risk compared CC genotype(OR=1.334, 95%CI 1.082-1.644). No significance among genotypes...