A5072658787- Head and Neck Cancer Studies
- Advanced Radiotherapy Techniques
- Breast Cancer Treatment Studies
- Radiomics and Machine Learning in Medical Imaging
- Colorectal and Anal Carcinomas
- Medical Imaging and Pathology Studies
- Inflammatory Biomarkers in Disease Prognosis
- Occupational and environmental lung diseases
- AI in cancer detection
- Radiation Dose and Imaging
- Colorectal Cancer Surgical Treatments
- Global Cancer Incidence and Screening
- Advances in Oncology and Radiotherapy
- COVID-19 and healthcare impacts
- Medical Imaging Techniques and Applications
- Pancreatic and Hepatic Oncology Research
- Pleural and Pulmonary Diseases
- Breast Lesions and Carcinomas
- Effects of Radiation Exposure
- Nonmelanoma Skin Cancer Studies
- Chemotherapy-related skin toxicity
- Colorectal Cancer Screening and Detection
- Cancer Immunotherapy and Biomarkers
Istituti di Ricovero e Cura a Carattere Scientifico
2020-2025
Centro di Riferimento Oncologico
2020-2025
Università degli Studi del Piemonte Orientale “Amedeo Avogadro”
2017-2018
Azienda Ospedaliero Universitaria Maggiore della Carita
2017-2018
BackgroundTo retrospectively evaluate the difference in terms of pathologic complete response (pCR) according to time elapsed between chemoradiation (CRT) and total mesorectal excision (TME) on a large unselected real-life dataset locally advanced rectal cancer (LARC) patients.MethodsA multicentre retrospective cohort study LARC patients from 21 Italian Radiotherapy Institutions was performed. Patients were stratified into 3 different intervals CRT. The 1st group included 300 who underwent...
Background: The Prognostic Nutritional Index (PNI) is a parameter of nutritional and inflammation status related to toxicity in cancer treatment. Since data for head neck are scanty, this study aims investigate the association between PNI acute late malignancy. Methods: A retrospective cohort 179 patients treated with definitive radiotherapy induction/concurrent chemotherapy was followed-up (median follow-up: 38 months) vital 2010 2017. calculated according Onodera formula low/high levels...
To date, accelerated partial breast irradiation (APBI) regimens are highly heterogeneous. Twice-daily schedules show comparable local control to whole-breast radiotherapy but with worse toxicity and cosmesis profiles. Conversely, once-daily better tolerated, though dose number of fractions yet not standardized. Therefore, the aim this study was evaluate efficacy tolerability three different APBI schedules. Three consecutive phase-2 trials were conducted at a single national cancer center...
When autocontouring based on artificial intelligence (AI) is used in the radiotherapy (RT) workflow, contours are reviewed and eventually adjusted by a radiation oncologist before an RT treatment plan generated, with purpose of improving dosimetry reducing both interobserver variability time for contouring. The this study was to evaluate results application commercial AI-based RT, assessing geometric accuracies influence optimized dose from automatically generated after review human...
Purpose: to predict the occurrence of late subcutaneous radiation induced fibrosis (RIF) after partial breast irradiation (PBI) for carcinoma by using machine learning (ML) models and radiomic features from 3D Biologically Effective Dose (3D-BED) Relative Electron Density (3D-RED). Methods: 165 patients underwent external PBI following a hypo-fractionation protocol consisting 40Gy/10 fractions, 35Gy/7 fractions 28Gy/4 73, 60 32 patients, respectively. Physicians evaluated toxicity at regular...
[18F] fluorodeoxyglucose positron emission tomography/computed tomography ([18F] FDG-PET/CT) may be used for tumor staging and prognosis in several tumors but its role rectal cancer is still debated. The aim of the present study was to assess correlation baseline FDG-PET parameters with staging, response (tumor regression grade (TRG)), outcome a series patients affected by locally advanced (LARC) treated neoadjuvant chemoradiotherapy (CRT). One hundred CRT radical surgery were enrolled...
Abstract Aim To evaluate the role of baseline neutrophil‐to‐lymphocyte ratio (NLR) as prognostic marker in squamous cell carcinoma oropharynx (OPC) treated with definitive chemoradiotherapy (CRT) era HPV status. Patients and methods A retrospective analysis 125 patients (pts) affected locally advanced OPC was performed. Inclusion criteria were age >18 years, stage III or IV (TNM 7th ed.) CRT. Haematological for their independent biomarkers progression‐free survival (PFS) overall (OS)....
Backgroundand purpose: Radiation recall dermatitis is an adverse event predominantly due to systemic therapy administration after a previous radiation course. Few case reports describe in breast cancer patients treated with postoperative following COVID-19 vaccination. In this study we investigated the incidence and severity of vaccination irradiated patients.MethodsPatients that received at least one dose during year end were included observational monocentric study. Local symptoms...
Purpose: to predict eligibility for deep inspiration breath-hold (DIBH) radiotherapy (RT) treatment of patients with left breast cancer from analysis respiratory signal, using Deep Bidirectional Long Short-Term Memory (BLSTM) recurrent neural networks. Methods: The traces 36 who underwent DIBH RT were collected. patients’ plans generated both and free-breathing (FB) modalities. divided into two classes (patient eligible or not), based on the decrease maximum dose anterior descending (LAD)...
Methods and materials: Patients with ongoing or planned anticancer treatment at 19 Italian Radiation Oncology centers were included in the study retrospectively from 3 February 2020 to 31 December prospectively 1 January 2021 May 2021. Anonymized data processed through a specific website database. Antineoplastic characteristics timing outcomes of COVID-19 its impact on radiotherapy systemic therapy described. Results: The retrieved cohort 41,039 patients that received for period. Overall,...
Randomised evidence supports the use of partial breast irradiation (PBI) with targeted intraoperative radiotherapy (TARGIT-IORT) for early stage cancer, but prospective data from real-world adoption this technique is also important. The aim study was to determine if outcome reported in TARGIT-A trial could be replicated large cohort cancer treated TARGIT-IORT.