Carlo Gobitti

ORCID: 0000-0003-4964-8046
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About
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Research Areas
  • Head and Neck Cancer Studies
  • Lung Cancer Treatments and Mutations
  • Lung Cancer Diagnosis and Treatment
  • Thyroid Cancer Diagnosis and Treatment
  • Cancer Diagnosis and Treatment
  • Head and Neck Surgical Oncology
  • Lung Cancer Research Studies
  • Radiopharmaceutical Chemistry and Applications
  • Advanced Radiotherapy Techniques
  • Glioma Diagnosis and Treatment
  • Salivary Gland Tumors Diagnosis and Treatment
  • Occupational and environmental lung diseases
  • Esophageal Cancer Research and Treatment
  • Pleural and Pulmonary Diseases
  • Viral-associated cancers and disorders
  • Colorectal and Anal Carcinomas
  • Ear and Head Tumors
  • Medical Imaging and Pathology Studies
  • Inflammatory Biomarkers in Disease Prognosis
  • Effects of Radiation Exposure
  • Brain Metastases and Treatment
  • Ovarian cancer diagnosis and treatment
  • Radiomics and Machine Learning in Medical Imaging
  • Radiation Dose and Imaging
  • Medical Imaging Techniques and Applications

Centro di Riferimento Oncologico
2013-2022

Istituti di Ricovero e Cura a Carattere Scientifico
1998-2022

Beatson West of Scotland Cancer Centre
2019

Turku University Hospital
2019

National Cancer Institute
2001-2007

The current study describes the clinicopathologic characteristics of 36 patients with lung carcinoma and human immunodeficiency virus (HIV) infection observed within Italian Cooperative Group on AIDS Tumors (GICAT).Patients HIV collected by GICAT between 1986-1998 were evaluated retrospectively. As a control group, authors analyzed 102 age < 60 years but without who seen at CRO, National Cancer Institute, Aviano, Italy 1995-1996.Patients younger (38 vs. 53 years) previously smoked more...

10.1002/(sici)1097-0142(20000201)88:3<563::aid-cncr11>3.0.co;2-d article EN Cancer 2000-02-01

Background: The Prognostic Nutritional Index (PNI) is a parameter of nutritional and inflammation status related to toxicity in cancer treatment. Since data for head neck are scanty, this study aims investigate the association between PNI acute late malignancy. Methods: A retrospective cohort 179 patients treated with definitive radiotherapy induction/concurrent chemotherapy was followed-up (median follow-up: 38 months) vital 2010 2017. calculated according Onodera formula low/high levels...

10.3390/nu13041277 article EN Nutrients 2021-04-13

Radiotherapy (RT) has a remarkable success rate in the treatment of patients with glottic carcinoma. The objectives current study were to assess results group consecutive comparable characteristics who treated RT (6-megavolt photon linear accelerator) and determine prognostic factors that may influence local control early-stage impact on tobacco smoking second primary malignancies also was investigated.Four hundred ten T1-T2 squamous cell carcinoma glottis between 1986 2001 analyzed...

10.1002/cncr.11575 article EN Cancer 2003-07-01

Abstract Aim To evaluate the role of baseline neutrophil‐to‐lymphocyte ratio (NLR) as prognostic marker in squamous cell carcinoma oropharynx (OPC) treated with definitive chemoradiotherapy (CRT) era HPV status. Patients and methods A retrospective analysis 125 patients (pts) affected locally advanced OPC was performed. Inclusion criteria were age &gt;18 years, stage III or IV (TNM 7th ed.) CRT. Haematological for their independent biomarkers progression‐free survival (PFS) overall (OS)....

10.1111/odi.13366 article EN Oral Diseases 2020-04-21

The incidence of thyroid disease is generally increasing, and it subject to major geographic variability, between within countries. Moreover, the rates proportion overdiagnosis for cancer in Italy are among highest worldwide. This study aimed estimate population-based frequency trends thyroidectomies by type surgical procedure (total/partial), indication (tumors/other conditions), sex, age, geographical region.

10.1089/thy.2021.0531 article EN Thyroid 2022-01-12

Abstract From January 1980 to May 1991, 28 patients with intraocular metastases were seen at our Institute. Three presented bilateral and two developed contralateral involvement. Out of the 33 ocular 27 managed by radiotherapy. The most common primary tumour sites breast (18/28 patients) lung (3/28). 22 treated an 8 MV linear accelerator, using a 4 × cm anterior direct field. median dose was 40 Gy/20 fractions (range Gy/14 50 Gy/25 fractions). Of treatments reported, 16 resulted in complete...

10.1259/0007-1285-66-788-699 article EN British Journal of Radiology 1993-08-01

Fluconazole is recommended in the prophylaxis of oropharyngeal candidiasis (OPC) patients undergoing radiotherapy for head-neck tumours; however, actual effectiveness fluconazole this setting remains unclear. Adult with cervico-cephalic carcinoma submitted to radical or adjuvant were randomized 100 mg (n = 138) matched placebo 132) oral suspension once daily from sixth session up end treatment. The final analysis investigation showed a higher rate OPC outbreak-free survival compared (P 0.008...

10.1111/j.1365-2354.2007.00855.x article EN European Journal of Cancer Care 2007-11-15

Objective: To evaluate whether plasma cell-free DNA (cfDNA) was related to clinical outcome in inoperable stage I non-small cell lung cancer (NSCLC) patients undergoing stereotactic body radiotherapy (SBRT).Materials and methods: Plasma cfDNA assessed at baseline, before the last day 45 days after end of SBRT, 22 NSCLC patients. Twenty-two healthy controls were also evaluated.Results: higher than controls. An association with unfavourable disease-free survival found for continuous baseline...

10.3109/1354750x.2015.1094139 article EN Biomarkers 2015-10-03

Concurrent chemo-radiotherapy is demonstrately superior to sequential in the treatment of advanced Non-Small-Cell Lung Cancer not suitable for surgery. Docetaxel considered enhance cytotoxic effect radiotherapy on tumour cells. Tomotherapy (HT) a novel radiotherapeutic technique, which allows delivery Image Guided-IMRT (IG-IMRT), with highly conformal radiation dose distribution. The goal study was estimate tolerability concurrent IMRT and find maximum tolerated weekly delivered HT after...

10.1186/1471-2407-13-513 article EN cc-by BMC Cancer 2013-10-31
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