A5071354389- Head and Neck Cancer Studies
- Lung Cancer Treatments and Mutations
- Lung Cancer Diagnosis and Treatment
- Lung Cancer Research Studies
- Immune Cell Function and Interaction
- Head and Neck Surgical Oncology
- Cancer Diagnosis and Treatment
- Viral-associated cancers and disorders
- Cancer-related molecular mechanisms research
- Occupational and environmental lung diseases
- Pleural and Pulmonary Diseases
- Lymphoma Diagnosis and Treatment
- Brain Metastases and Treatment
- Glioma Diagnosis and Treatment
- Advanced Radiotherapy Techniques
- Medical Imaging Techniques and Applications
- MicroRNA in disease regulation
- Immunotherapy and Immune Responses
- Radiomics and Machine Learning in Medical Imaging
- Esophageal Cancer Research and Treatment
- Radiopharmaceutical Chemistry and Applications
- Management of metastatic bone disease
- RNA modifications and cancer
- Salivary Gland Tumors Diagnosis and Treatment
- Ear and Head Tumors
Centro di Riferimento Oncologico
2015-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2015-2024
Bristol-Myers Squibb (United States)
2024
MemorialCare Health System
2022
National Cancer Institute
2000-2018
Albert Einstein College of Medicine
2004
Tohoku Medical and Pharmaceutical University Hospital
1984
Azienda Ospedaliera Santa Maria Degli Angeli
1982
Abstract Objectives Deep learning-based auto-segmentation of head and neck cancer (HNC) tumors is expected to have better reproducibility than manual delineation. Positron emission tomography (PET) computed (CT) are commonly used in tumor segmentation. However, current methods still face challenges handling whole-body scans where a selection bounding box may be required. Moreover, different institutions might apply guidelines for This study aimed at exploring the auto-localization...
To compare the accuracy of magnetic resonance (MR) imaging and combined fluorine 18 fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed (CT), alone in combination, detection restaging treated nasopharyngeal carcinoma (NPC).This retrospective study was performed after institutional review board approval informed consent were obtained. Sixty-three consecutive patients for NPC underwent follow-up with both MR FDG PET/CT. Findings evaluated according to TNM classification. Final...
Cendakimab selectively targets interleukin (IL)-13, a type 2 cytokine implicated in atopic dermatitis (AD) pathogenesis, by inhibiting binding to its receptors (IL13R-α1 and IL13R-α2). Proof-of-concept work AD supports using cendakimab for inflammatory diseases.
Twenty-two consecutive patients with recurrent malignant brain tumors after radiation therapy and systemic combination chemotherapy BCNU vincristine, four of whom were not evaluable due to early death, treated etoposide (VP-16-213) (50-100 mg/m2 for five days every three weeks). Response, defined as improvement in both clinical examination computed tomography scan absence glucocorticoids dosage increase, was observed (17%) 18 patients, lasting greater than 21, seven, two months,...
Between June 1980 and December 1983, 111 patients with inoperable epidermoid bronchogenic carcinoma (limited disease) were entered into a randomized trial comparing radiotherapy alone versus combination chemotherapy cyclophosphamide, Adriamycin (doxorubicin), methotrexate, procarbazine. Thirty-five of 62 (56.4%) treated 4500 rad in 15 fractions 3 weeks 19 49 (38.8%) the same radiation treatment had an objective response. The difference response rate was not significant (P = 0.900). Median...
Background: The Prognostic Nutritional Index (PNI) is a parameter of nutritional and inflammation status related to toxicity in cancer treatment. Since data for head neck are scanty, this study aims investigate the association between PNI acute late malignancy. Methods: A retrospective cohort 179 patients treated with definitive radiotherapy induction/concurrent chemotherapy was followed-up (median follow-up: 38 months) vital 2010 2017. calculated according Onodera formula low/high levels...
Radiotherapy (RT) has a remarkable success rate in the treatment of patients with glottic carcinoma. The objectives current study were to assess results group consecutive comparable characteristics who treated RT (6-megavolt photon linear accelerator) and determine prognostic factors that may influence local control early-stage impact on tobacco smoking second primary malignancies also was investigated.Four hundred ten T1-T2 squamous cell carcinoma glottis between 1986 2001 analyzed...
Purpose: Head and neck squamous cell carcinomas (HNSCCs) cause more than 300,000 deaths worldwide each year. Locoregional distant recurrences represent worse prognostic events accepted surrogate markers of patients' overall survival. No valid biomarker salvage therapy exist to identify treat patients at high-risk recurrence. We aimed verify if selected miRNAs could be used as biomarkers recurrence in HNSCC.Experimental Design: A NanoString array was associated with locoregional 44 HNSCC....
Deep learning models based on medical images play an increasingly important role for cancer outcome prediction. The standard approach involves usage of convolutional neural networks (CNNs) to automatically extract relevant features from the patient's image and perform a binary classification occurrence given clinical endpoint. In this work, 2D-CNN 3D-CNN distant metastasis (DM) in head neck patients were extended time-to-event analysis. newly built CNNs incorporate censoring information...
Inclusion of new biomarkers to improve a personalized treatment approach for oropharyngeal squamous cell carcinoma (OPSCC) is urgently needed. Hypomethylation the Long interspersed nucleotide element-1 (LINE-1) repetitive elements, widely accepted surrogate overall genomic DNA methylation content, was found be associated with poor prognosis in several cancers. At present, no studies have investigated influence LINE-1 levels on OPSCC relapse. The main goal this study evaluation prognostic...