A5004692487- Pharmaceutical Practices and Patient Outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Medication Adherence and Compliance
- Patient Safety and Medication Errors
- Healthcare Decision-Making and Restraints
- Injury Epidemiology and Prevention
- Child and Adolescent Health
- Frailty in Older Adults
- Traffic and Road Safety
- Blood Pressure and Hypertension Studies
- Cardiovascular Syncope and Autonomic Disorders
- Sports injuries and prevention
- Pharmacovigilance and Adverse Drug Reactions
- Cardiovascular Health and Disease Prevention
- Migration, Health and Trauma
- Genomics, phytochemicals, and oxidative stress
- Vasculitis and related conditions
- Cardiac, Anesthesia and Surgical Outcomes
- Chronic Disease Management Strategies
- Venous Thromboembolism Diagnosis and Management
- Balance, Gait, and Falls Prevention
- Healthcare cost, quality, practices
- Retinal and Optic Conditions
- Glutathione Transferases and Polymorphisms
- Romani and Gypsy Studies
Brighton and Sussex Medical School
2016-2023
University Hospitals Sussex NHS Foundation Trust
2018-2022
University of Sussex
2014-2022
Seaford Day Hospital
2021
National Health Service
2018
Lewisham and Greenwich NHS Trust
2015
Royal Sussex County Hospital
2015
King's College London
2010-2011
University of Edinburgh
2010
King's College - North Carolina
2010
Polypharmacy is increasingly common in older adults, placing them at risk of medication-related harm (MRH). Patients are particularly vulnerable to problems with their medications the period following hospital discharge due medication changes and poor information transfer between primary care. The aim present study was investigate incidence, severity, preventability cost MRH adults England postdischarge.An observational, multicentre, prospective cohort recruited 1280 (median age 82 years)...
Electronic health records are invaluable for pregnancy-related studies. The Clinical Practice Research Datalink (CPRD) Pregnancy Register (PR) identifies pregnancies in primary care records, including uncertain cases. This paper outlines a method to reduce uncertainty identifying within CPRD GOLD PR data, exemplified through study investigating the provision of pre-pregnancy care. We used Mother Baby Link (MBL) and Maternity Hospital Episode Statistics (HES) clean augment data. included all...
To develop and validate a tool to predict the risk of an older adult experiencing medication-related harm (MRH) requiring healthcare use following hospital discharge.
Falls are a major public health concern in the older population, and certain medication classes significant risk factor for falls. However, knowledge is lacking among both physicians people, including caregivers, concerning role of as factor. In present statement, European Geriatric Medicine Society (EuGMS) Task Finish group on fall-risk-increasing drugs (FRIDs), collaboration with EuGMS Special Interest Pharmacology Union Medical Specialists (UEMS) Section, outlines its position regarding...
Abstract Background Optimising women's pre-pregnancy health is a policy priority for benefits spanning pregnancy and throughout the mother baby's life. In UK care (PPC) tends to be delivered in primary care, with onus on women seek services. We aimed describe women’s engagement General Practice (GP) year preceding pregnancy, including specific PPC; explore whether recognised risk factors poor outcomes receive targeted care. Methods Data aged 18-48yrs registered $$\ge$$ <mml:math...
Rugby union is the most popular worldwide collision sport, yet concerns have been raised regarding safety of sport due to physical, high impact nature and an increasing number injuries. A prospective, cohort study incidence, pattern severity injuries in rugby players six Scottish schools during second half 2008–09 season. Definition injury were taken from International Board (IRB) consensus guidelines. Injury report forms exposure data for match play completed by a nominated staff member....
To determine the association between frailty and medication-related harm requiring healthcare utilisation.
Medication related harm (MRH) is a common cause of morbidity and hospital admission in the elderly, has significant cost implications for both primary secondary healthcare resources. The development risk prediction models become an increasingly phenomenon medicine can be useful to guide objective clinical decision making, resource allocation intervention. There are no that widely used practice identify elderly patients at high MRH following discharge. aim this study develop model (RPM) upon...
Abstract Purpose To investigate whether inappropriate prescribing, defined by the Beers Criteria, is associated with medication‐related harm (MRH), hospital admission, and mortality in older adults England. Methods A multicentre, prospective cohort study recruited 1280 patients (median age 82 years) at discharge. Patients were followed‐up community pharmacists for 8 weeks to identify MRH (harm from adverse drug reactions, non‐adherence, medication errors) admissions. One‐year was determined...
medication-related problems (MRP) are common for older adults and can lead to harm. The person's perspective on MRP has been seldom reported in published literature. This study explored the lived experience of with varying functional levels, focussing hospital discharge period. this qualitative was conducted Brighton Hove, UK. A purposive sample 20 people MRP, involving carers, took part focus groups semi-structured interviews. Data were thematically analysed using a 'framework' approach....
The communication of injury risk in rugby and other sports is underdeveloped parents, children coaches need to be better informed about risk.A Poisson distribution was used transform population based incidence into average probabilities individual players.The schoolboy matches range from 7 129.8 injuries per 1000 player-hours; these rates translate a player between 12% 90% over season.Incidence season should published together all future epidemiological studies on school sports. More...
Medication-related harm (MRH) is common in older adults following hospital discharge. In resource-limited health systems, interventions to reduce this risk can be targeted at high-risk patients. This study aims determine whether (1) doctors predict which patients will experience MRH requiring healthcare discharge, (2) clinical and confidence prediction influence the accuracy of prediction.This was a multicentre observational prospective involving five teaching hospitals England between...
Objectives The Medication Appropriateness Tool for Comorbid Health conditions in Dementia (MATCH-D) criteria provide expert consensus guidance about medication use people with dementia. This study aimed to identify enablers and barriers implementing the practice. Setting Participants came from both rural metropolitan communities two Australian states. Focus groups were held consumers, general practitioners, nurses pharmacists. Outcomes: data analysed thematically. Results Nine focus...
Injury is a leading cause of death among children and adolescents accounts for around 16% the world’s burden disease reflecting disproportionate injuries young people added years life lived with disability. It poorest in every country world that are at greatest risk injury majority deaths due to child occur low-income middle-income countries. The can be prevented or least controlled costs prevention much lower than consequences injuries. But requires good quality data monitoring surveillance...
Abstract Susceptibility to adverse drug reactions (ADRs), multimorbidity, and frailty are associated with human aging, yet there is wide variation in the severity age at which individuals afflicted. Identifying genetic markers of increased risk this phenotype would help stratify specialist interventions. Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) regulates a cell’s response stressors, including expression enzymes involved metabolism. Its has been shown decline animal aging models. In...