- Traumatic Brain Injury Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiac Arrest and Resuscitation
- EEG and Brain-Computer Interfaces
- Functional Brain Connectivity Studies
- Neurological disorders and treatments
- Neural dynamics and brain function
- Psychosomatic Disorders and Their Treatments
- Neuroscience and Neural Engineering
- Sleep and Wakefulness Research
- Advanced Neuroimaging Techniques and Applications
- Genetic Neurodegenerative Diseases
- Visual perception and processing mechanisms
- Heart Rate Variability and Autonomic Control
- Intensive Care Unit Cognitive Disorders
- Advanced MRI Techniques and Applications
- Epilepsy research and treatment
- Anesthesia and Neurotoxicity Research
- Anesthesia and Sedative Agents
- Transcranial Magnetic Stimulation Studies
- Neuroscience and Neuropharmacology Research
- Blind Source Separation Techniques
- Memory and Neural Mechanisms
- Neonatal and fetal brain pathology
- Cerebrospinal fluid and hydrocephalus
Cornell University
2016-2025
MIND Research Institute
2016-2025
Weill Cornell Medicine
2016-2024
Athinoula A. Martinos Center for Biomedical Imaging
2024
Harvard University
2018-2024
Spaulding Rehabilitation Hospital
2018-2024
Massachusetts General Hospital
2018-2024
NewYork–Presbyterian Hospital
1998-2024
Presbyterian Hospital
1998-2024
New York Hospital Queens
1998-2024
Neuroplasticity can be defined as the ability of nervous system to respond intrinsic or extrinsic stimuli by reorganizing its structure, function and connections. Major advances in understanding neuroplasticity have date yielded few established interventions. To advance translation research towards clinical applications, National Institutes Health Blueprint for Neuroscience Research sponsored a workshop 2009. Basic researchers disciplines from central injury/stroke, mental/addictive...
Dynamic patterns of brain activity at rest distinguish conscious and unconscious states in humans.
Despite advances in resting state functional magnetic resonance imaging investigations, clinicians remain with the challenge of how to implement this paradigm on an individualized basis. Here, we assessed clinical relevance acquisitions patients disorders consciousness by means a systems-level approach. Three centres collected data from 73 minimally conscious state, vegetative state/unresponsive wakefulness syndrome and coma. The main analysis was performed set coming one centre (Liège)...
Functional neuroimaging methods hold promise for the identification of cognitive function and communication capacity in some severely brain-injured patients who may not retain sufficient motor to demonstrate their abilities. We studied seven a control group 14 subjects using novel hierarchical functional magnetic resonance imaging assessment utilizing mental imagery responses. Whereas showed consistent accurate (for communication) blood-oxygen-level-dependent responses without exception,...
In this era of complete genomes, our knowledge neuroanatomical circuitry remains surprisingly sparse. Such is however critical both for basic and clinical research into brain function. Here we advocate a concerted effort to fill gap, through systematic, experimental mapping neural circuits at mesoscopic scale resolution suitable comprehensive, brain-wide coverage, using injections tracers or viral vectors. We detail the scientific medical rationale briefly review existing techniques. define...
Objective To update the 1995 American Academy of Neurology (AAN) practice parameter on persistent vegetative state and 2002 case definition minimally conscious (MCS) provide care recommendations for patients with prolonged disorders consciousness (DoC). Methods Recommendations were based systematic review evidence, related principles, inferences using a modified Delphi consensus process according to AAN 2011 manual, as amended. Clinicians should identify treat confounding conditions,...
Patients with brain injury who are unresponsive to commands may perform cognitive tasks that detected on functional magnetic resonance imaging (fMRI) and electroencephalography (EEG). This phenomenon, known as motor dissociation, has not been systematically studied in a large cohort of persons disorders consciousness.