Allan R. Jones
- Single-cell and spatial transcriptomics
- Gene expression and cancer classification
- Cell Image Analysis Techniques
- Bioinformatics and Genomic Networks
- Neuroinflammation and Neurodegeneration Mechanisms
- Neural dynamics and brain function
- Neuroscience and Neuropharmacology Research
- Neurogenesis and neuroplasticity mechanisms
- Functional Brain Connectivity Studies
- Photoreceptor and optogenetics research
- Laser-induced spectroscopy and plasma
- Neuroscience and Neural Engineering
- Congenital heart defects research
- Combustion and flame dynamics
- Epigenetics and DNA Methylation
- Plasma and Flow Control in Aerodynamics
- Combustion and Detonation Processes
- Advanced Biosensing Techniques and Applications
- Graphite, nuclear technology, radiation studies
- Advanced Power Generation Technologies
- Photosynthetic Processes and Mechanisms
- Neurobiology and Insect Physiology Research
- Sleep and Wakefulness Research
- Genomics and Phylogenetic Studies
- Health, Environment, Cognitive Aging
Allen Institute for Brain Science
2013-2022
Allen Institute
2013-2022
Baker Hughes (United States)
2022
KU Leuven
2020
Evangelical Theological Faculty
2020
Temple University
2015
University of Johannesburg
2014
Imperial College London
1971-2008
Aarhus University
2007
University of South Florida
2006
Bombardment of three mutants the chloroplast atpB gene Chlamydomonas reinhardtii with high-velocity tungsten microprojectiles that were coated cloned DNA carrying wild-type permanently restored photosynthetic capacity algae. In most transformants one mutants, a fragment 2.5-kilobase deletion was to normal size by homologous replacement event; in about 25 percent restriction 50 100 base pairs smaller or larger than wild type. About one-fourth this mutant contained unintegrated donor plasmid...
INTRODUCTION The brain is responsible for cognition, behavior, and much of what makes us uniquely human. development the a highly complex process, this process reliant on precise regulation molecular cellular events grounded in spatiotemporal transcriptome. Disruption can lead to neuropsychiatric disorders. RATIONALE regulatory, epigenomic, transcriptomic features human have not been comprehensively compiled across time, regions, or cell types. Understanding etiology disorders requires...
Glioblastoma is an aggressive brain tumor that carries a poor prognosis. The tumor's molecular and cellular landscapes are complex, their relationships to histologic features routinely used for diagnosis unclear. We present the Ivy Atlas, anatomically based transcriptional atlas of human glioblastoma aligns individual with genomic alterations gene expression patterns, thus assigning information most important morphologic hallmarks tumor. its clinical database freely accessible online data...
ABSTRACT Detailed anatomical understanding of the human brain is essential for unraveling its functional architecture, yet current reference atlases have major limitations such as lack whole‐brain coverage, relatively low image resolution, and sparse structural annotation. We present first digital atlas to incorporate neuroimaging, high‐resolution histology, chemoarchitecture across a complete adult female brain, consisting magnetic resonance imaging (MRI), diffusion‐weighted (DWI), 1,356...
In this era of complete genomes, our knowledge neuroanatomical circuitry remains surprisingly sparse. Such is however critical both for basic and clinical research into brain function. Here we advocate a concerted effort to fill gap, through systematic, experimental mapping neural circuits at mesoscopic scale resolution suitable comprehensive, brain-wide coverage, using injections tracers or viral vectors. We detail the scientific medical rationale briefly review existing techniques. define...