Kevin Joines

ORCID: 0000-0003-2340-4369
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About
Contact & Profiles
Research Areas
  • Cell Image Analysis Techniques
  • Neural dynamics and brain function
  • Global Cancer Incidence and Screening
  • Bioinformatics and Genomic Networks
  • Lung Cancer Diagnosis and Treatment
  • Palliative Care and End-of-Life Issues
  • Frailty in Older Adults
  • Neuroscience and Neuropharmacology Research
  • Single-cell and spatial transcriptomics
  • bioluminescence and chemiluminescence research
  • Photoreceptor and optogenetics research
  • Patient-Provider Communication in Healthcare
  • Microtubule and mitosis dynamics
  • Neuroscience and Neural Engineering
  • Biotin and Related Studies
  • Colorectal Cancer Screening and Detection

Allen Institute
2014-2018

Allen Institute for Brain Science
2014-2018

Glioblastoma is an aggressive brain tumor that carries a poor prognosis. The tumor's molecular and cellular landscapes are complex, their relationships to histologic features routinely used for diagnosis unclear. We present the Ivy Atlas, anatomically based transcriptional atlas of human glioblastoma aligns individual with genomic alterations gene expression patterns, thus assigning information most important morphologic hallmarks tumor. its clinical database freely accessible online data...

10.1126/science.aaf2666 article EN Science 2018-05-10

ABSTRACT As an anterograde neuronal tracer, recombinant adeno‐associated virus (AAV) has distinct advantages over the widely used biotinylated dextran amine (BDA). However, sensitivity and selectivity of AAV remain uncharacterized for many brain regions species. To validate this tracing method further, (serotype 1) was systematically compared with BDA as tracer by injecting both tracers into three cortical 15 subcortical in C57BL/6J mice. Identical parameters were our sequential...

10.1002/cne.23567 article EN The Journal of Comparative Neurology 2014-02-24

ABSTRACT As an anterograde neuronal tracer, recombinant adeno‐associated virus (AAV) has distinct advantages over the widely used biotinylated dextran amine (BDA). However, sensitivity and selectivity of AAV remain uncharacterized for many brain regions species. To validate this tracing method further, (serotype 1) was systematically compared with BDA as tracer by injecting both tracers into three cortical 15 subcortical in C57BL/6J mice. Identical parameters were our sequential...

10.1002/cne.23587 article EN The Journal of Comparative Neurology 2014-04-19
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