Karan Kumar

ORCID: 0000-0003-0012-8314
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About
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Research Areas
  • Enzyme Catalysis and Immobilization
  • Microbial Metabolic Engineering and Bioproduction
  • Biofuel production and bioconversion
  • Enzyme Production and Characterization
  • Biodiesel Production and Applications
  • Pesticide Exposure and Toxicity
  • Free Radicals and Antioxidants
  • Protein Hydrolysis and Bioactive Peptides
  • Food Industry and Aquatic Biology
  • Hydrogen Storage and Materials
  • Microbial Fuel Cells and Bioremediation
  • Catalysis for Biomass Conversion
  • Biomedical Ethics and Regulation
  • Water-Energy-Food Nexus Studies
  • Effects of Environmental Stressors on Livestock
  • Natural Products and Applications
  • Antenna Design and Analysis
  • Antenna Design and Optimization
  • Muscle Physiology and Disorders
  • Immunotoxicology and immune responses
  • Microbial Metabolites in Food Biotechnology
  • Aquaculture Nutrition and Growth
  • Advanced Combustion Engine Technologies
  • Porphyrin Metabolism and Disorders
  • Bioeconomy and Sustainability Development

Indian Institute of Technology Guwahati
2019-2024

Touro College
2021

Mayo Clinic
2007

Abstract Bacteria from diverse genera, including Acetivibrio , Bacillus Cellulosilyticum Clostridium Desulfotomaculum Lachnoclostridium Moorella Ruminiclostridium and Thermoanaerobacterium have attracted significant attention due to their versatile metabolic capabilities encompassing acetogenic, cellulolytic, C 1 ‐metabolic properties, acetone‐butanol‐ethanol fermentation. Despite biotechnological significance, a comprehensive understanding of clostridial physiology evolution has remained...

10.1002/bit.28610 article EN Biotechnology and Bioengineering 2023-12-04

Abstract This study investigates acetone-butanol-ethanol (ABE) fermentation, a process using solventogenic Clostridium species to produce acetone, butanol, and ethanol. Recent biotechnological advancements, such as omics, systems biology, metabolic engineering, have reignited interest in butanol production, responding the increasing gasoline costs demand for sustainable energy systems. unravels distinct physiological attributes of C. acetobutylicum ( Cac ) pasteurianum Cpa ), significantly...

10.1101/2023.12.08.570763 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2023-12-08

Abstract Second generation alcoholic biofuels synthesis from lignocellulosic biomass (LB) consists three steps viz., pre-treatment, detoxification, and fermentation. This dilute acid pre-treatment process generates several compounds like acids, aldehydes, ketones, oxides their phenolic derivatives that are potential inhibitors of some the crucial enzymes in metabolic pathway ABE With application hybrid quantum mechanics/ molecular mechanics (QM/MM) approach, our aim is to discern mechanism...

10.1101/2022.11.19.517192 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2022-11-22

The purpose of this literature review is to gain an overview the role platelet-activating factor (PAF) within each body systems and how it contributes normal pathophysiological states. showed that there are multiple functions PAF common several systems; however, little evidence explain why has affect across systems. Interestingly, seems be conflicting research as whether overall protective or pathogenic pathway. Within research, was found different pathways depending on specific system, well...

10.3390/hearts2040042 article EN cc-by Hearts 2021-11-29

Ultrasound has emerged as an efficient green technology for intensification of lipase-catalyzed processes. These processes are high significance in the context renewable fuels synthesis. In this paper, we have attempted to reveal molecular mechanism sonication-induced enhancement lipase-catalysed reactions. Using hybrid quantum mechanics/ mechanics computations, initially determined structure and amino acid composition binding pockets two common lipase enzyme, viz. CALB TLL . Next, these...

10.22541/au.166722851.12958171/v1 preprint EN Authorea (Authorea) 2022-10-31

n-Butyl levulinate (n-BL) has numerous applications in biofuel and green solvents. In this paper, we have reported mechanistic accounts of sonoenzymatic synthesis n-BL using Novozym 435. Esterification parameters were optimized with statistical design experiments. Application 35 kHz sonication boosted yield from 70.9% to 92.22%. Mechanistic investigation Ping-Pong Bi-Bi kinetics model molecular docking simulations revealed interesting influence on esterification reaction. Exposure induced...

10.22541/au.170666363.34692682/v1 preprint EN Authorea (Authorea) 2024-01-31
Tia Utami Mathieu Danoy Rubina Rahaman Khadim Fumiya Tokito Hiroshi Arakawa and 95 more Yukio Kato Taketomo Kido Atsushi Miyajima Masaki Nishikawa Yasuyuki Sakai Anju Anil Maruthai Kavitha Alvaro R. Lara José Utrilla Luz María Martínez Niels Krausch Lucas Kaspersetz David Hidalgo Nicolás Cruz-Bournazou Peter Neubauer Juan‐Carlos Sigala Guillermo Gosset Jochen Büchs Hamid Khodabandehlou Mohammad Rashedi Tony Wang Aditya Tulsyan Gregg Schorner Christopher Garvin Cenk Ündey Lena Gaugler Sebastian Hofmann Michael Schlüter Ralf Takors Richard Wu B.C.M. Chan Zac Sarich Yaokai Duan Janice Chen Jiu‐Li Song Mike Berke Les P. Miranda Chetan T. Goudar Romain Kinet Anne Richelle Michael Colle Didier Demaegd Von Moritz Matthew Stosch Hannah Sanders Frank Sehrt Philippe Delvigne Young Lyun Oh M. R. Becker Kerri M. Mendola Leila H. Choe Kelvin H. Lee Yinges Yigzaw Alexander Seay Jerome Bill Xuanwen Li David J. Roush Steven M. Cramer Stefano Menegatti Abraham M. Lenhoff Karan Kumar Lepakshi Barbora Vijayanand S. Moholkar Isabela De Oliveira Pereira Ângela Dos Santos Nick Candiotto Guimarães C. R. de O. Lima Eduardo Zanella Akinori Matsushika Sarita Cândida Rabelo Boris U. Stambuk Jaciane Lutz Ienczak Maximilienne Toetie Allaart Charilaos Korkontzelos Diana Sousa Robbert Kleerebezem Keqi Wang Wei Xie Sarah W. Harcum Florian Klingler Patrick Schlossbauer Lukas Naumann René Handrick Friedemann Hesse Christian Neusüß Kerstin Communication Goran Mihajlović Victoria Rashid Jia Sodré Timothy Luo Matthias Nöbel Craig Barry M. A. MacDonald Kym Baker

10.1002/bit.28708 article EN Biotechnology and Bioengineering 2024-03-30
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