A5014531785- Breast Cancer Treatment Studies
- Breast Lesions and Carcinomas
- MRI in cancer diagnosis
- Medical Imaging Techniques and Applications
- Cancer Genomics and Diagnostics
- Radiomics and Machine Learning in Medical Imaging
- Global Cancer Incidence and Screening
- Breast Implant and Reconstruction
- Digital Radiography and Breast Imaging
- Cancer Immunotherapy and Biomarkers
- Anatomy and Medical Technology
- Cancer Diagnosis and Treatment
- AI in cancer detection
- Cancer Cells and Metastasis
- Surgical Simulation and Training
- Advanced Breast Cancer Therapies
- Cancer and Skin Lesions
- Digital Imaging in Medicine
- Cancer Treatment and Pharmacology
- Advanced MRI Techniques and Applications
- Radiopharmaceutical Chemistry and Applications
- BRCA gene mutations in cancer
- Advanced X-ray and CT Imaging
- Ultrasound and Hyperthermia Applications
- HER2/EGFR in Cancer Research
The University of Texas MD Anderson Cancer Center
2015-2024
University of Puerto Rico System
2024
Nektar Therapeutics (United States)
2021
Dana-Farber Cancer Institute
2019
The University of Texas Health Science Center at Houston
2018
Roche (Switzerland)
2016
Varian Medical Systems (Germany)
2016
Novartis (Switzerland)
2016
Purpose Placing clips in nodes with biopsy-confirmed metastasis before initiating neoadjuvant therapy allows for evaluation of response breast cancer. Our goal was to determine if pathologic changes clipped reflect the status nodal basin and targeted axillary dissection (TAD), which includes sentinel lymph node (SLND) selective localization removal nodes, improves false-negative rate (FNR) compared SLND alone. Methods A prospective study patients metastases a clip placed sampled performed....
Medical three-dimensional (3D) printing has expanded dramatically over the past three decades with growth in both facility adoption and variety of medical applications. Consideration for each step required to create accurate 3D printed models from imaging data impacts patient care management. In this paper, a writing group representing Radiological Society North America Special Interest Group on Printing (SIG) provides recommendations that have been vetted voted by SIG active membership....
Objective: To determine the accuracy of fine-needle aspiration (FNA) and vacuum-assisted core biopsy (VACB) in assessing presence residual cancer breast after neoadjuvant systemic therapy (NST). Summary Background Data: Pathologic complete response (pCR) rates NST have improved dramatically, suggesting that surgery might be avoided some patients. Safe avoidance would require accurate confirmation no invasive/in situ carcinoma. Methods: Forty patients with T1-3N0-3 triple-negative or...
This purpose of this study is to describe the imaging findings in patients who presented with a diagnosis primary breast sarcoma.A search was performed pathology database at single institution for histopathologic sarcoma or pure sarcomatoid carcinoma and underwent preoperative mammography, sonography, MRI. Patients malignant phyllodes tumors were excluded. The studies retrospectively reviewed using American College Radiology BI-RADS lexicon. We documented clinical presentation,...
Abstract Patient-derived xenograft (PDX) models of breast cancer are an effective discovery platform and tool for preclinical pharmacologic testing biomarker identification. We established orthotopic PDX triple negative (TNBC) from the primary tumors patients prior to following neoadjuvant chemotherapy (NACT) while they were enrolled in ARTEMIS trial (NCT02276443). Serial biopsies obtained treatment (pre-NACT), poorly responsive disease after four cycles Adriamycin cyclophosphamide (AC,...
High stromal tumor-infiltrating lymphocytes (sTILs) are associated with improved pathologic complete response (pCR) in triple-negative breast cancer (TNBC). We hypothesize that integrating high sTILs and additional clinicopathologic features pCR could enhance our ability to predict the group of patients on whom treatment de-escalation strategies be tested. In this prospective early-stage TNBC neoadjuvant chemotherapy study, pretreatment biopsies from 408 were evaluated for their clinical...
Objective: To determine the relationship between negative margin width and locoregional recurrence (LRR) in a contemporary cohort of ductal carcinoma situ (DCIS) patients. Background: Recent national consensus guidelines recommend an optimal 2 mm or greater for management DCIS; however, controversy regarding re-excision remains when managing margins <2 mm. Methods: One thousand four hundred ninety-one patients with DCIS who underwent breast-conserving surgery from 1996 to 2010 were...
The purpose of this article is to describe the feasibility and safety a multidisciplinary approach imaging-guided axillary staging that facilitates personalized, less invasive surgical management axilla through targeted dissection in patients with biopsy-proven nodal metastasis undergoing neoadjuvant chemotherapy.Axillary status, critical breast cancer staging, affects prognosis treatment. As paradigm shifts toward minimally therapy, clip marker placed biopsied metastatic node for N1-N2...
Medical 3D printing has demonstrated value in anatomic models for abdominal, hepatobiliary, and gastrointestinal conditions. A writing group composed of the Radiological Society North America (RSNA) Special Interest Group on Printing (SIG) provides appropriateness criteria indications.A literature search was conducted to identify all relevant articles using technology associated with a number abdominal pathologic processes. Each included study graded according published...
PURPOSE The PI3K pathway is frequently altered in triple-negative breast cancer (TNBC). Limited cell line and human data suggest that TNBC tumors characterized as mesenchymal (M) luminal androgen receptor (LAR) subtypes have increased incidence of alterations the pathway. impact across poorly understood. METHODS Pretreatment tumor was evaluated from operable patients enrolled on a clinical trial neoadjuvant therapy (NAT; A Robust Evaluation fraMework to Improve Survival [ClinicalTrials.gov...
The use of medical 3D printing has expanded dramatically for breast diseases. A writing group composed the Radiological Society North America (RSNA) Special Interest Group on Printing (SIG) provides updated appropriateness criteria in various clinical scenarios. Evidence-based are provided following scenarios: benign lesions and high-risk lesions, cancer, reconstruction, radiation (treatment planning delivery).
Adenomyoepithelial Tumors of the Breast: Imaging Findings With Histopathologic CorrelationMargaret Adejolu1 2, Yun Wu3, Lumarie Santiago1 and Wei T. Yang1Audio Available | Share
Abstract Background Advancements in three-dimensional (3D) printing have enabled production of patient-specific guides to aid perforator mapping and pedicle dissection during abdominal flap harvest. We present our early experience using this tool navigate deep inferior epigastric artery (DIEA) topography evaluate its impact on operative efficiency clinical outcomes. Patients Methods Between January 2013 December 2018, a total 50 women underwent computed tomographic angiography (CTA)-guided...