A5004065744- Nonmelanoma Skin Cancer Studies
- Polyomavirus and related diseases
- Cutaneous Melanoma Detection and Management
- melanin and skin pigmentation
- Skin Protection and Aging
- Cancer and Skin Lesions
- Genetic and rare skin diseases.
- RNA regulation and disease
- Hair Growth and Disorders
- Cutaneous lymphoproliferative disorders research
- Hereditary Neurological Disorders
- Autoimmune Bullous Skin Diseases
- Cytomegalovirus and herpesvirus research
- Herpesvirus Infections and Treatments
- Tumors and Oncological Cases
- Parkinson's Disease Mechanisms and Treatments
- Head and Neck Anomalies
- Oral and Maxillofacial Pathology
- Restless Legs Syndrome Research
- interferon and immune responses
- Lymphoma Diagnosis and Treatment
- Vascular Tumors and Angiosarcomas
- Sarcoidosis and Beryllium Toxicity Research
- Cancer-related gene regulation
- CNS Lymphoma Diagnosis and Treatment
University of Verona
2022-2023
University of Florida Health
2020-2023
University of Florida
2016-2022
Florida College
2018-2021
Hospital Central de la Defensa Gómez Ulla
2019
University of Milan
2016
Nordic Lymphoma Group
2013
Hospital General Universitario Gregorio Marañón
2000-2010
University of Pennsylvania
2003
Fondazione Ricerca Molinette
1995
Primary cutaneous γδ T-cell lymphomas (PCGD-TCLs) are considered a subgroup of aggressive cytotoxic (CTCLs). We have taken advantage new, commercially available antibody that recognizes the receptor-γ (TCR-γ) subunit TCR in paraffin-embedded tissue. analyzed series 146 primary received for consultation or second opinion CNIO Pathology Department. Cases were classified according to World Health Organization 2008 classification as mycosis fungoides (MF; n=96), PCGD-TCLs (n=5), pagetoid...
Vorinostat (suberoylanilide hydroxamic acid, SAHA), an inhibitor of class I and II histone deacetylases, has been approved for the treatment cutaneous T-cell lymphoma. In spite emerging information on effect vorinostat in many types cancer, little is yet known about this drug's mechanism action, which essential its proper use combination therapy. We investigated alterations gene expression profile over time lymphoma cells treated with vorinostat. Subsequently, we evaluated inhibitors PI3K,...
Although considered as a first-group carcinogen, indoor tanning is common practice in Europe. Euromelanoma pan-European skin cancer prevention campaign.To compare several European countries terms of the prevalence and determinants sunbed use.Participants campaigns filled questionnaires containing demographics risk factors, including type/duration use. Multivariate analyses adjusted for age, gender, education, type year survey were employed to assess factors independently associated with use...
Sunbed use has been significantly associated with increased risk of melanoma and non-melanoma skin cancer (NMSC), but its relationship melanoma's factors such as high nevus count, atypical nevi lentigines is poorly studied. Euromelanoma a prevention campaign conducted all over Europe. It offers once-a-year screening during which participants' data, including sunbed phenotype, are collected via questionnaires.To investigate the association nevi, suspicion cancer.To ensure reliability we...
Treatment of recalcitrant warts in solid organ transplant recipients (SOTR) can pose a therapeutic challenge for dermatologists. Successful treatment serve as secondary prevention skin cancer those with chronic immunosuppression. Given the heterogeneity associated comorbid conditions SOTR, clinical trials are difficult to conduct this high-risk population, therefore, our practice is mostly driven by observed responses from studies immunocompetent patients or case reports immunocompromised...
The use of UV-emitting tanning devices for cosmetic purposes is associated with an increased risk melanoma and non-melanoma skin cancer. Young women are the most frequent users, therefore, there increasing concern about regulation sunbed use.The primary objective to assess current legislation on among European countries.We developed a 30-item questionnaire gather relevant information legislation. was sent Euromelanoma coordinators designated out network.We obtained response rate 64%. More...
There is little information about neuropsychiatric comorbidities in Charcot-Marie-Tooth disease (CMT). We assessed frequency of anxiety, depression, and general distress CMT.We administered online the Hospital Anxiety-Depression Scale (HADS) to CMT patients Italian registry controls. HADS-A HADS-D scores ≥ 11 defined presence anxiety/depression HADS total score (HADS-T) 22 distress. analysed correlation with severity clinical characteristics, use anxiolytics/antidepressants...
Drug-induced sarcoidosis has been rarely described but it constitutes a potential side effect of immunomodulatory medications. We report case rituximab-induced scar and review similar published cases. Although there is evidence B-cell dysregulation in the pathogenesis sarcoidosis, use rituximab for this disease needs to be carefully evaluated based on reports worsening de novo development after therapy.
Solid organ and stem cell transplant recipients have an increased risk of developing cutaneous infections, which often are refractory to conventional treatment (Euvrard et al., Journal the American Academy Dermatology, 2001, 44, 932-939). Molluscum contagiosum, a common self-limited disease primarily affecting children, can be more severe unresponsive therapy in patients (Gardner & Ormond, Clinical Experimental 2006, 31, 452-453). Candida immunotherapy has been widely used for warts,...
Sleep abnormalities have been reported in Charcot-Marie-Tooth disease (CMT), but data are scanty. We investigated their presence and correlation a large CMT patients' series.Epworth Sleepiness Scale (ESS) Pittsburgh Quality Index (PSQI) were administered to patients of the Italian registry controls. ESS score > 10 indicated abnormal daytime somnolence, PSQI 5 bad sleep quality. analyzed with severity characteristics, Hospital Anxiety Depression (HADS), Modified Fatigue Impact (MFIS), Body...
BACKGROUND Adequate sun protection practices in chronically immunosuppressed patients can minimize the burden of most common type skin cancer this population. In addition, early recognition by lead to decreased morbidity, and possibly mortality from disease. Nevertheless, there are significant gaps knowledge measures cancer. OBJECTIVE The aim study is determine risk factors solid organ transplant recipients (SOTRs) for developing their exposure education behavior post-transplantation....
An 8-year-old male lion with progressive lack of secondary sex characteristics, dysorexia and weight loss was referred to our Institution.The patient anaesthetized undergo general clinical evaluation, hematologic, serum biochemical hormonal profile, FIV/FeLV tests.Total body computed tomography, abdominal ultrasonography fine-needle aspirates the liver left adrenal lesion were performed.Imaging findings showed presence a neoplastic on gland generalized hepatopathy.Blood tests reported an...
Reactive angioendotheliomatosis (RAE) is an uncommon, benign, antiproliferative condition associated with systemic diseases that may cause occlusion or inflammation of the vascular lumina. A link between antiphospholipid syndrome (APS) and RAE has been reported a few times in literature. Herein, we present unique case diagnosed patient primary APS who was well-managed on warfarin rituximab no recent thrombotic events. As can precede follow diagnosis APS, presence indicates need to workup for...