A5059527919- Gastrointestinal motility and disorders
- Helicobacter pylori-related gastroenterology studies
- Gastroesophageal reflux and treatments
- Diet and metabolism studies
- Gastrointestinal disorders and treatments
- Pancreatic and Hepatic Oncology Research
- Esophageal and GI Pathology
- Pancreatitis Pathology and Treatment
- Gastric Cancer Management and Outcomes
- Bariatric Surgery and Outcomes
- Gallbladder and Bile Duct Disorders
- Intestinal Malrotation and Obstruction Disorders
- Myofascial pain diagnosis and treatment
- Clinical Nutrition and Gastroenterology
- Biliary and Gastrointestinal Fistulas
- Eosinophilic Esophagitis
- Microscopic Colitis
- Inflammatory Bowel Disease
- Appendicitis Diagnosis and Management
- Asymmetric Synthesis and Catalysis
- Intraperitoneal and Appendiceal Malignancies
- Gut microbiota and health
- Acupuncture Treatment Research Studies
- Synthetic Organic Chemistry Methods
- Colorectal Cancer Screening and Detection
Cleveland State University
2025
Texas Tech University
2015-2024
Texas Tech University Health Sciences Center
2015-2024
Southern Arizona VA Health Care System
2019
William Beaumont Army Medical Center
2017
The University of Texas Health Science Center at Houston
2012-2014
The University of Texas at El Paso
2010-2014
New York State Psychiatric Institute
2011
New York Psychoanalytic Society and Institute
2011
Columbia University
2011
The advent and use of highly sensitive molecular biology techniques to explore the microbiota microbiome in environmental tissue samples have detected presence contaminating microbial DNA within reagents. These contaminants may distort taxonomic distributions relative frequencies datasets, as well contribute erroneous interpretations identifications. We herein report on occurrence bacterial contamination commonly used extraction kits PCR reagents effect these contaminates data...
Since Crohn's disease is a transmural disease, we hypothesized that examination of deep submucosal tissues directly involved in the inflammatory process may provide unique insights into bacterial populations transgressing intestinal barriers and more representative causes agents disease. We performed 16s microbiota sequencing on isolated ilea mucosal 20 patients with 15 non-inflammatory bowel controls depth coverage averaging 81,500 sequences each 70 DNA samples yielding an overall...
Abstract Background Depletion and ultrastructural changes of interstitial cells Cajal ( ICC ) in the gastric body antrum have been observed gastroparesis. This research was performed to investigate population muscularis propria fibrosis muscular layer pylorus Methods Full thickness pyloric antral biopsies were obtained from 17 gastroparetic 6 non‐gastroparetic controls. Biopsies stained with C‐Kit for Trichrome collagen fibrosis. Interstitial depletion defined as mean count <10 per 20...
In adult animals, the medial prefrontal cortex (mPFC) plays a significant role in regulating emotions and projects to amygdala periaqueductal gray (PAG) modulate emotional responses. However, little is known about development of this neural circuit its relevance unlearned fear pre-adulthood. To address these issues, we examined mPFC 14-d-old (infants), 26-d-old (juveniles), 38- 42-d-old (adolescents) rats represent different developmental social milestones. The expression patterns neuronal...
Complicated cholecystitis can make dissections around the triangle of Calot difficult with a higher risk duct and arterial injury. We reviewed series patients receiving either partial or subtotal cholecystectomies compared it total respect to complications. A retrospective chart review was performed on all for at University Medical Center El Paso from June 2004 December 2010. similar number who had were selected as comparison group that same time period. 116 (58 in each group). There seven...
Crohn's disease is characterized by increased permeability of the intestinal mucosal barriers and an abnormal or dysregulated immune response to specific and/or commensal bacteria arising from lumen. To determine types that are transgressing barrier colonizing submucosal tissues, we performed 16S rRNA gene microbiota sequencing tissues at advancing margin in ileal disease. Microbial populations were compared between mucosa submucosa non-inflammatory bowel (non-IBD) controls, as well...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis and biological evaluation of a monocyclic, fully functional analog compactinClayton H. Heathcock, Brian R. Davis, Cheri HadleyCite this: J. Med. Chem. 1989, 32, 1, 197–202Publication Date (Print):January 1989Publication History Published online1 May 2002Published inissue 1 January 1989https://pubs.acs.org/doi/10.1021/jm00121a036https://doi.org/10.1021/jm00121a036research-articleACS PublicationsRequest reuse permissionsArticle...
Staple line leaks are a serious problem in bariatric surgery and major cause of morbidity mortality. Adverse events caused by medical devices reported to the Food Drug Administration which maintains Manufacturer User Facility Device Experience (MAUDE) database. We examined adverse stapler MAUDE database, specifically with regards surgery.The database was queried for staplers between January 1, 2018 - December 31, 2020; Intuitive, Ethicon, Medtronic/Covidien; limited our search "gastric...
Objective: To determine whether bacterial pathogens can be detected within the diseased submucosal tissues of patients with Crohn's disease by molecular techniques independent cultural methods. Design: We designed a quantitative polymerase chain reaction to detect 32 virulence genes and transposons controls compared microbiome submucosa mucosal populations. Results: Within tissues, invasion/adherence eaeA invA were in 43% (P=0.01 0.008 vs. mucosa controls, respectively)...