A5012841148- Smoking Behavior and Cessation
- Child Nutrition and Water Access
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Screening and Detection
- Child Nutrition and Feeding Issues
- School Health and Nursing Education
- Cervical Cancer and HPV Research
- Global Cancer Incidence and Screening
- Statistical Methods and Bayesian Inference
- Statistical Methods and Inference
- Nutritional Studies and Diet
- Behavioral Health and Interventions
- COVID-19 and healthcare impacts
- Viral gastroenteritis research and epidemiology
- Advanced Statistical Methods and Models
- Long-Term Effects of COVID-19
- Substance Abuse Treatment and Outcomes
- Sexual function and dysfunction studies
- Digital Mental Health Interventions
- Advanced MRI Techniques and Applications
- Cardiovascular Conditions and Treatments
- Cardiac Health and Mental Health
- Mobile Health and mHealth Applications
- Sodium Intake and Health
- Health Literacy and Information Accessibility
University of Virginia
2020-2025
University of Virginia Health System
2022-2024
Texas Tech University
2012-2020
The University of Texas at El Paso
2014-2020
American Headache Society
2020
New York Proton Center
2020
Charlottesville Medical Research
2020
Texas Tech University Health Sciences Center
2012-2019
Baylor College of Medicine
2017
University of Pennsylvania
2017
Experimental studies in biomedical research frequently pose analytical problems related to small sample size. In such studies, there are conflicting findings regarding the choice of parametric and nonparametric analysis, especially with non‐normal data. instances, some methodologists questioned validity tests suggested tests. contrast, other found be too conservative less powerful thus preferred using Some researchers have recommended a bootstrap test; however, this method also has size...
Background & AimsEnvironmental enteric dysfunction (EED) limits the Sustainable Development Goals of improved childhood growth and survival. We applied mucosal genomics to advance our understanding EED.MethodsThe Study Environmental Enteropathy Malnutrition (SEEM) followed 416 children from birth 24 months in a rural district Pakistan. Biomarkers were measured at 9 tested for association with months. The duodenal methylome transcriptome determined 52 undernourished SEEM participants 42 North...
Gonadectomy is widely used to treat and prevent behavior problems including the aggressive of dogs. The aim this study was determine whether toward familiar people, strangers, or other dogs significantly different in gonadectomized at various ages vs. intact using Canine Behavioral Assessment Research Questionnaire (C-BARQ) with multivariate analysis. Of 15,370 initial surveys, those for reported have been less than 6 weeks age correct a problem, incomplete answers questions regarding...
In two population-based cohorts, we did not find an independent relationship between albuminuria and ILA, with age emerging as a key confounding factor. Our results suggest there may be common systemic pathology of aging that underlies ILA. Background Pulmonary microvascular dysfunction has been suggested to early feature interstitial lung changes, which precede disease (ILD). The prospective association albuminuria, marker endothelial dysfunction, abnormalities (ILA) high-attenuation areas...
To assess the endoscopic characteristics of gastric polyps and their association with Helicobacter pylori (H. pylori) status in a predominantly Hispanic population.We conducted retrospective study all esophagogastroduodenoscopies performed at our institution. Demographic, histopathological data were reviewed. Categorization patients into Non-Hispanic was based on self-identification. Patients without resection/biopsy not included analysis. Identification type histological examination. One...
Studying the effect of exposure or intervention on a dichotomous outcome is very common in medical research. Logistic regression (LR) often used to determine such association which provides odds ratio (OR). OR overestimates size for prevalent data. In situations, use relative risk (RR) has been suggested. We propose modifications Zhang and Yu Diaz-Quijano methods. These methods were compared with stratified Mantel Haenszel method, LR, log binomial (LBR), Poisson/Cox regression, modified...
Introduction Environmental enteropathy is an important contributor to childhood malnutrition in the developing world. Chronic exposure fecal pathogens leads alteration intestinal structure and function, resulting impaired gut immune malabsorption, growth faltering leading environmental enteropathy. Methods A community-based intervention study was carried out on children till 24 months of age Matiari district, Pakistan. Blood specimens were collected from enrolled aged 3–6 9 months. real-time...
To characterize patterns of fruit and vegetable (F&V) intake in US adults with without chronic kidney disease (CKD).We used 24-hour dietary recall data from multiple cycles the National Health Nutrition Examination Survey spanning 3 groups 1988 to 2018 (1988-1994; 2003-2010; 2011-2018). We categorized F&Vs based on food processing phytochemical content. assessed using latent class analysis compared across temporal cohorts CKD status weighted multinomial logistic regression.Four similar...
We previously found that type 2 immunity promotes coronavirus disease 2019 (COVID-19) pathogenesis in a mouse model. To test relevance to human disease, we used electronic health record databases and determined patients on dupilumab (anti-interleukin [IL]-4R monoclonal antibody blocks IL-13 IL-4 signaling) at the time of COVID-19 infection had lower mortality.
Recent genome-wide association studies (GWASs) have identified numerous putative genetic polymorphisms associated with bipolar disorder (BD) and/or schizophrenia (SC). We hypothesized that a portion of these would also be BD in the Latino American population. To identify such regions, we tested previously variants SC and ancestral haploblocks containing single nucleotide (SNPs) sample subjects BD.A total 2254 individuals were genotyped for 91 SNPs previous GWASs, along selected strong...
Intestinal inflammation and malabsorption in environmental enteric dysfunction (EED) are associated with early childhood growth faltering impoverished settings worldwide. The goal of this study was to identify candidate biomarkers inflammation, EED histology, as predictors later outcomes by focusing on the liver-gut axis investigating bile acid metabolome. Undernourished rural Pakistani infants (n = 365) weight-for-height Z score (WHZ) < -2 were followed up age 24 mo monitored for growth,...
Background Alcohol misuse is the fourth leading cause of death in United States and a significant problem US military. Brief alcohol interventions can reduce negative outcomes civilian military populations, but additional scalable are needed to binge heavy drinking. SMS text messaging could address this need, date, no programs exist for populations. Objective We aimed develop an intervention drinking among Airmen Technical Training Air Force. Methods implemented 2-phase, mixed methods study...