A5073431138- Respiratory viral infections research
- Congenital Diaphragmatic Hernia Studies
- Influenza Virus Research Studies
- Vaccine Coverage and Hesitancy
- Climate Change and Health Impacts
- Pneumonia and Respiratory Infections
- Respiratory Support and Mechanisms
- Viral gastroenteritis research and epidemiology
- COVID-19 Clinical Research Studies
- Neonatal Respiratory Health Research
- COVID-19 Impact on Reproduction
- Emergency and Acute Care Studies
- Virology and Viral Diseases
- Tracheal and airway disorders
- Viral Infections and Vectors
- SARS-CoV-2 and COVID-19 Research
- Child and Adolescent Health
- Viral Infections and Outbreaks Research
- Infection Control and Ventilation
- Kawasaki Disease and Coronary Complications
- COVID-19 epidemiological studies
- Healthcare and Environmental Waste Management
- Global Health Care Issues
- Healthcare cost, quality, practices
- Global Maternal and Child Health
The University of Sydney
2019-2025
Children's Hospital at Westmead
2018-2025
Taronga Conservation Society Australia
2023
National Centre for Immunisation Research & Surveillance
2018-2022
Sydney Children’s Hospitals Network
2018-2022
Sydney Children's Hospital
2019-2020
Nepean Hospital
2020
Hunter New England Local Health District
2020
University of Newcastle Australia
2020
National Centre for Research
2019
School closures have occurred globally during the COVID-19 pandemic. However, empiric data on transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among children and in educational settings are scarce. In Australia, most schools remained open first epidemic wave, albeit with reduced student physical attendance at peak. We examined SARS-CoV-2 staff early childhood education care (ECEC) Australian state New South Wales (NSW).Laboratory-confirmed paediatric (aged ≤18...
COVID-19 public health measures altered respiratory syncytial virus (RSV) epidemiology. We examined age-stratified trends in RSV-related disease Australian children 2020 compared with previous years.
Acute respiratory infections cause significant paediatric morbidity, but for pathogens other than influenza, syncytial virus (RSV), and SARS-CoV-2, systematic monitoring is not commonly performed. This retrospective analysis of six years routinely collected pathogen multiplex PCR testing at a major hospital in New South Wales Australia, describes the epidemiology, year-round seasonality, co-detection patterns 15 viral pathogens. 32,599 samples from children aged under 16 were analysed. Most...
Objective To estimate rates of respiratory syncytial virus (RSV)-associated hospitalisation across the age spectrum, and to identify groups at particular risk serious RSV-associated disease. Design, setting participants Retrospective review National Hospital Morbidity Database data for all hospitalisations in Australia, 2006–2015. Main outcomes measures RSV-coded by age, sex, Indigenous status, jurisdiction, seasonality (month year); hospital length stay; in-hospital deaths. Results During...
The Immunization Agenda 2030 emphasises the need for a motivated, skilled and knowledgeable workforce equipped to plan, manage, implement monitor immunisation programmes at all levels. rapid introduction of COVID-19 vaccines during pandemic highlighted adaptability health but also exposed gaps in professional development learning. This practice paper describes implementation an training programme Kingdom Cambodia Lao People’s Democratic Republic. was developed delivered by project team...
To describe the severity and clinical spectrum of coronavirus disease 2019 (COVID-19) in children during 2021 New South Wales outbreak Delta variant severe acute respiratory syndrome 2 (SARS-CoV-2).Prospective cohort study three metropolitan Sydney local health districts, 1 June - 31 October 2021.Children under 16 years age with positive SARS-CoV-2 nucleic acid test results admitted to hospital or managed by Children's Hospital Network (SCHN) virtual care team.Age-specific infection...
The interdependence between healthy people and a planet is increasingly recognized. 'The Lancet Countdown on Health Climate Change' has called for 'people-centred', health-driven transformation to combat the effects of climate change (Romanello et al., 2023). In 2023, United Nations Change Conference (COP28) was first its kind include health as core theme reflecting formal recognition impacts health, community's role in addressing this challenge. Simultaneously, there an increasing desire...
Introduction The Paediatric Active Enhanced Disease Surveillance (PAEDS) network is a hospital-based active surveillance system employing prospective case ascertainment for selected serious childhood conditions, particularly vaccine preventable diseases and potential adverse events following immunisation (AEFI). PAEDS data used to better understand these inform policy practice under the National Immunisation Program, enable rapid public health responses certain conditions of importance....
Aim Respiratory syncytial virus (RSV) is a leading cause of acute lower respiratory tract infections in children and the development vaccines to protect at‐risk groups global priority. The aim this study was describe RSV subtype circulation patterns associated disease severity inform on potential impact an RSV‐specific prevention strategy. Methods Single‐centre retrospective observational aged <16 years with laboratory‐confirmed infection from 2014 2018 inclusive. We described features...
Respiratory syncytial virus (RSV) is the leading cause of acute lower respiratory infections (ALRIs) in children <2 years age. Currently, there are limited data on risk factors for very severe RSV-ALRI requiring intensive care unit (ICU) admission.
Bronchiolitis is a common respiratory illness and leading cause of hospitalisation in infancy. We aimed to appraise three recent national bronchiolitis guidelines produced by the Australasian Paediatric Research Emergency Departments International Collaborative, National Institute for Health Care Excellence UK American Academy Pediatrics.A group final-year medical students one senior clinician used AGREE II tool each guideline two stages. First, appraised independently presented their...
The Paediatric Active Enhanced Disease Surveillance (PAEDS) network is a hospital-based active surveillance system employing prospective case ascertainment for selected serious childhood conditions, particularly vaccine-preventable diseases and potential adverse events following immunisation (AEFI). This report presents data 2017 2018.Specialist nurses screened hospital admissions, emergency department (ED) records, laboratory other on daily basis in seven paediatric tertiary referral...
Aim To identify and describe potentially vaccine‐preventable child deaths in New South Wales (NSW). Methods Child NSW from 2005 to 2014 preventable by vaccination were identified the Death Register (maintained Ombudsman) Notifiable Conditions Information Management System (NSW Health). Medical post‐mortem records reviewed. Cases classified as based on strength of evidence for relevant infection causing death likelihood that was through vaccination. A two‐source capture–recapture method used...
ABSTRACT Objective(s) To describe the severity and clinical spectrum of SARS-CoV-2 infection in Australian children during 2021 Delta outbreak. Design, Setting & Participants A prospective cohort study <16 years with a positive nucleic acid test cared for by Sydney Children’s Hospital Network (SCHN) virtual inpatient medical teams between 1 June – 31 October 2021. Main outcome measures Demographic data from all admitted patients random sample outpatients managed under SCHN care team...
<sec> <title>BACKGROUND</title> Electronic immunisation registers (EIRs) have been promoted as health system strengthening tools that, if used effectively, can lead to greater efficiency and improvements in vaccination coverage. Several low-and-middle-income countries (LMICs) introduced EIRs for COVID-19 are now integrating them routine immunisation. </sec> <title>OBJECTIVE</title> This paper describes the protocol evaluate implementation of an EIR Lao PDR, that started 2022, identify...
Abstract Background Respiratory syncytial virus (RSV) is the leading cause of acute lower respiratory infections (ALRIs) associated hospitalisations in children. It unclear if hospitalized RSV-ALRI differs clinically from other viral ALRIs. We aimed to compare disease impact hospitalised RSV with ALRI children under 2 years. Methods conducted a retrospective study using electronic medical records ALRIs at Sydney Children’s Hospitals Network 2020-2022. compared demographics and clinical...
Respiratory syncytial virus (RSV) is a leading cause of acute lower respiratory tract infection and an important contributor to child mortality. In this study, we estimated the frequency described clinical features RSV-attributable deaths in Australian children.We conducted retrospective observational study RSV-associated hospitalized children <16 years age over 21-year period (1998-2018) pediatric tertiary/quaternary referral hospital New South Wales (NSW), Australia. were identified,...