- Abdominal Surgery and Complications
- COVID-19 and healthcare impacts
- Cardiac, Anesthesia and Surgical Outcomes
- Advanced MRI Techniques and Applications
- Hernia repair and management
- Appendicitis Diagnosis and Management
- Colorectal Cancer Surgical Treatments
- Intraperitoneal and Appendiceal Malignancies
- Intestinal and Peritoneal Adhesions
- Medical Imaging Techniques and Applications
- Nutrition and Health in Aging
- Gallbladder and Bile Duct Disorders
- Sarcoma Diagnosis and Treatment
- Trauma and Emergency Care Studies
- Minimally Invasive Surgical Techniques
- Pelvic floor disorders treatments
- Respiratory Support and Mechanisms
- Gynecological conditions and treatments
- Clinical practice guidelines implementation
- Assisted Reproductive Technology and Twin Pregnancy
- Primary Care and Health Outcomes
- Advanced X-ray Imaging Techniques
- Healthcare cost, quality, practices
- Atomic and Subatomic Physics Research
- Thermoregulation and physiological responses
University Hospital of Wales
2015-2025
Cardiff and Vale University Health Board
2021-2022
Cardiff University
2022
Sheffield Teaching Hospitals NHS Foundation Trust
2020
Royal College of Surgeons of Edinburgh
2019-2020
Royal College of Anaesthetists
2019-2020
Royal College of Surgeons of England
2019-2020
Northern General Hospital
2019-2020
Crescent University
2019
University of Edinburgh
2019
The COVID-19 pandemic led to widespread disruption of colorectal cancer services during 2020. Established referral pathways were modified in response reduced diagnostic availability. aim this paper is assess the impact on referral, presentation and stage.This was a single centre, retrospective cohort study performed at tertiary centre. Patients diagnosed managed with adenocarcinoma between January December 2020 compared patients from 2018 2019 terms demographics, mode pathological staging.In...
Abstract Aim Incisional Hernia (IH) is a common complication of colorectal surgery, affecting up to 30% patients. There an association between surgeon experience and outcomes in hernia yet little regarding impact the performing abdominal wall closure (AWC) on IH rate. We aimed assess rates at 1 year following AWC junior senior surgeons patients undergoing surgery. Method This exploratory analysis who participated Hughes Abdominal Repair Trial (HART), prospective, multicentre randomised...
Correlations of energy state with response to therapy are more difficult analyze because the large effect tumor clearing and oxygenation upon as detected by PMRS alone. The combination time-resolved hemoglobinometry using picosecond laser technology localized seems appropriate unravel complexities therapeutic intervention, energetics, oxygenation.
Background. Protein calorie malnutrition, which is highly prevalent in tumor-bearing hosts, increases toxicity to 5-fluorouracil (5-FU), but the mechanisms are unclear. This study investigated effects of protein depletion on 5-FU vivo hepatic metabolism using F19-nuclear magnetic resonance spectroscopy (19F-NMRS). Methods. Rats received normal (21.5%) or low (2.5%) diet for 25 days. was injected intraperitoneally, and fluorine spectra were obtained. Parallel experiments conducted determine...
Twenty-three patients with bone and soft tissue tumors were studied combined magnetic resonance (MR) imaging spectroscopy. The MR examinations utilized to determine the size, internal characteristics, relationships of tumor surrounding tissues. They also determined optimal placement surface coil. coil profile was localization technique utilized. Four one-dimensional chemical shift localization. Tumors grouped according histologic type, degree muscle contamination, extent necrosis....
Eighteen patients with soft tissue masses underwent integrated magnetic resonance imaging (MRI) and phosphorus spectroscopy (31P-MRS) to evaluate benign malignant tumor morphology metabolism. Spectra from tumors had a significantly higher proportion of phosphate in the low-energy portion 31P spectrum (P < 0.001) concomitant decrease phosphocreatine 0.01) compared spectra normal muscle. Malignant mean pH 7.35 ± 0.13 which was greater than that muscle 7.08 0.07 0.001). All relative levels...
Incisional hernia (IH) is a common complication of colorectal surgery, affecting up to 30% patients at 2 years. Given the associated morbidity and high recurrence rates after attempted repair IH, emphasis should be placed on prevention. There an association between surgeon volume outcomes in yet there little evidence regarding impact seniority performing abdominal wall closure IH rate. The aim our study was assess 1 year following junior senior surgeons undergoing elective surgery.This...
The use of standard CO2 for insufflation during laparoscopic colorectal surgery may be associated with cooling and drying the peritoneal cavity, contributing to perioperative hypothermia. aim this work was assess feasibility a study compare warmed, humidified (WHCO2) (using HumiGard, Fisher Paykel Healthcare) measures its impact on quality recovery surgical patients.A single-centre, triple-blind, feasibility, randomized controlled trial (RCT) adults scheduled planned surgery. primary outcome...
The COVID-19 pandemic has caused unprecedented health care challenges mandating surgical service reconfiguration. Within our hospital, emergency and elective streams were separated self-contained Protected Elective Surgical Units developed to mitigate against infection-related morbidity. Aims of this study determine the risk transmission mortality whether development can result in significant reduction risk.A retrospective observational consecutive patients from 18 specialties undergoing or...
Abstract Introduction There is an association between surgeon volume and outcomes in hernia surgery, yet little evidence regarding impact of the experience performing abdominal wall closure (AWC) on IH rate. Our aim was to assess rates at 1 year following surgery Registrar Consultant surgeons patients undergoing elective colorectal surgery. Methods Patients for cancer 2014-2018 were identified through Hughes Abdominal Repair Trial (HART). Grade AWC categorised into “Trainee” “Consultant”...
Faecal incontinence (FI) is a debilitating symptom with likely underreported incidence in the general population. Postpartum or postmenopausal women are at increased risk of this. General Practitioners (GPs) have vital role screening patient groups FI. Knowledge underlying diseases associated FI important for all clinicians who contact this group. An online questionnaire (Survey MonkeyTM, San Mateo, CA, USA) was sent to GPs Wales and England through deanery, social media GP educational...