A5020202434- Advanced Radiotherapy Techniques
- Radiation Therapy and Dosimetry
- Particle physics theoretical and experimental studies
- bioluminescence and chemiluminescence research
- Medical Imaging Techniques and Applications
- Photochemistry and Electron Transfer Studies
- Prostate Cancer Diagnosis and Treatment
- Ocular Oncology and Treatments
- Advanced X-ray and CT Imaging
- Muon and positron interactions and applications
- High-Energy Particle Collisions Research
- Radiation Detection and Scintillator Technologies
- Radiation Dose and Imaging
- Superconducting Materials and Applications
- Quantum Chromodynamics and Particle Interactions
- Computational Physics and Python Applications
- Radical Photochemical Reactions
- Sarcoma Diagnosis and Treatment
- Chemical Reactions and Isotopes
- Free Radicals and Antioxidants
- Nuclear Physics and Applications
- Bone Tumor Diagnosis and Treatments
- Boron Compounds in Chemistry
- Ocular Infections and Treatments
- Photoreceptor and optogenetics research
Massachusetts General Hospital
2014-2023
Harvard University
2013-2023
Institute of Biochemical Physics NM Emanuel
1996-2023
Kazan State Technological University
2017-2021
Institute of Mining
2019
Far Eastern Federal University
2018
Russian Academy of Sciences
1996-2015
University of Würzburg
1996-2009
Boston University
1999-2009
Harvard University Press
2007
We present the final report from a series of precision measurements muon anomalous magnetic moment, ${a}_{\ensuremath{\mu}}=(g\ensuremath{-}2)/2$. The details experimental method, apparatus, data taking, and analysis are summarized. Data obtained at Brookhaven National Laboratory, using nearly equal samples positive negative muons, were used to deduce ${a}_{\ensuremath{\mu}}(\mathrm{\text{Expt}})=11659208.0(5.4)(3.3)\ifmmode\times\else\texttimes\fi{}{10}^{\ensuremath{-}10}$, where...
The anomalous magnetic moment of the negative muon has been measured to a precision 0.7 ppm (ppm) at Brookhaven Alternating Gradient Synchrotron. This result is based on data collected in 2001, and over an order magnitude more precise than previous measurement for muon. a(mu(-))=11 659 214(8)(3) x 10(-10) (0.7 ppm), where first uncertainty statistical second systematic, consistent with measurements anomaly positive average a(mu)(exp)=11 208(6) (0.5 ppm).
We propose and study a unified model for handling dose constraints (physical dose, equivalent uniform (EUD), etc) radiation source in single mathematical framework based on the split feasibility problem. The does not impose an exogenous objective (merit) function. optimization algorithm minimizes weighted proximity function that measures sum of squares distances to constraint sets. This guarantees convergence feasible solution point if problem is consistent (i.e., has solution), or,...
A precise measurement of the anomalous g value, a(mu) = (g-2)/2, for positive muon has been made at Brookhaven Alternating Gradient Synchrotron. The result a(mu+) 11 659 202(14) (6) x 10(-10) (1.3 ppm) is in good agreement with previous measurements and an error one third that combined data. current theoretical value from standard model a(mu)(SM) 159.6(6.7) (0.57 a(mu)(exp) - 43(16) which world average experimental value.
Three independent searches for an electric dipole moment (EDM) of the positive and negative muons have been performed, using spin precession data from muon g-2 storage ring at Brookhaven National Laboratory. Details on experimental apparatus three analyses are presented. Since individual results muon, as well combined result, d=-0.1(0.9)E-19 e-cm, all consistent with zero, we set a new EDM limit, |d| < 1.9E-19 e-cm (95% C.L.). This represents factor 5 improvement over previous best limit EDM.
A higher precision measurement of the anomalous g value, a(mu)=(g-2)/2, for positive muon has been made at Brookhaven Alternating Gradient Synchrotron, based on data collected in year 2000. The result a(mu(+))=11 659 204(7)(5)x10(-10) (0.7 ppm) is good agreement with previous measurements and an error about one-half that combined data. present world average experimental value a(mu)(expt)=11 203(8)x10(-10) ppm).
Treatment delivery with active beam scanning in proton radiation therapy introduces the problem of interplay effects when pencil motion occurs on a similar time scale as intra-fractional tumor motion. In situations where fractionation may not provide enough repetition to blur interplay, repeated or 'repainting' each field several times within fraction has been suggested. The purpose this work was investigate effectiveness different repainting strategies scanning. To assess dosimetric impact...
We present a method to include robustness in multi-criteria optimization (MCO) framework for intensity-modulated proton therapy (IMPT). The approach allows one simultaneously explore the trade-off between different objectives as well and nominal plan quality. In MCO, database of plans each emphasizing treatment planning objectives, is pre-computed approximate Pareto surface. An IMPT that strikes best balance can be selected by navigating on our approach, integrated into MCO adding...
A significant and increasing number of patients receiving radiation therapy present with metal objects close to, or even within, the treatment area, resulting in artifacts computed tomography (CT) imaging, which is most commonly used imaging method for planning therapy. In presence implants, such as dental fillings head-and-neck tumors, spinal stabilization implants paraspinal hip replacements prostate cancer treatments, extreme photon absorption by object leads to prominent image artifacts....
Received 22 August 2002DOI:https://doi.org/10.1103/PhysRevLett.89.129903©2002 American Physical Society
With proton beam radiation therapy a smaller volume of normal tissues is irradiated at high dose levels for most anatomic sites than feasible with any photon technique. This due to the Laws Physics, which determine absorption energy from photons and protons. In other words, decreases exponentially depth in material. contrast, protons have finite range that dependent. Accordingly, by appropriate distribution energies, can be uniform across target essentially zero deep atomic composition The...
With the recent availability of 4D-CT, accuracy information on internal organ motion during respiration has improved significantly. We investigate utility in IMRT treatment planning, using an in-house prototype optimization system. Four approaches are compared: (1) planning with optimized margins, based information; (2) 'motion kernel' approach, which a more accurate description dose deposit from pencil beam to moving target is achieved either through time-weighted averaging influence...