Lie Wu

ORCID: 0000-0003-0184-2106
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Research Areas
  • Nanoplatforms for cancer theranostics
  • Advanced Nanomaterials in Catalysis
  • Advanced Photocatalysis Techniques
  • MXene and MAX Phase Materials
  • Extracellular vesicles in disease
  • 2D Materials and Applications
  • Advanced biosensing and bioanalysis techniques
  • Electrochemical sensors and biosensors
  • Advanced Sensor and Energy Harvesting Materials
  • Advanced Memory and Neural Computing
  • Electrocatalysts for Energy Conversion
  • Nanocluster Synthesis and Applications
  • Biosensors and Analytical Detection
  • Conducting polymers and applications
  • Polydiacetylene-based materials and applications
  • Graphene and Nanomaterials Applications
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Peptidase Inhibition and Analysis
  • Advancements in Battery Materials
  • Surface Modification and Superhydrophobicity
  • Colorectal and Anal Carcinomas
  • Lightning and Electromagnetic Phenomena
  • Protease and Inhibitor Mechanisms
  • Advanced Fiber Optic Sensors
  • Nicotinic Acetylcholine Receptors Study

Shenzhen Institutes of Advanced Technology
2017-2025

Chinese Academy of Sciences
2017-2025

Wuhan University of Science and Technology
2025

Changchun Institute of Applied Chemistry
1996-2023

University of Chinese Academy of Sciences
2020-2022

Zhejiang Cancer Hospital
2015-2020

First Affiliated Hospital of Shantou University Medical College
2008

Shantou University
2008

Wenzhou University
2005

Baylor College of Medicine
1995

Implant-related infections are serious complications after bone surgery and can compromise the intended functions of artificial implants, leading to surgical failure even amputation in severe cases. Various strategies have been proposed endow implants with desirable antibacterial properties, but unfortunately, most them inevitably suffer from some side effects detrimental normal tissues. In this study, a multifunctional implant is designed work conjunction sequential photothermal mediation,...

10.1021/acsnano.1c06062 article EN ACS Nano 2021-10-27

Nanomedicines intergrating both therapy and diagnosis functions provide a promising strategy for anticancer treatment. As novel two-dimensional materials, black phosphorus nanosheets (BPs) possess unique properties biomedical applications, pratically photothermal (PTT) of cancer, but their lack air water stability may hinder application. Herein, covalent functionalization based on Nile Blue (NB) dye via diazonium chemistry is established to modify BPs, not only enhancing the BPs also...

10.1021/acs.chemmater.7b01106 article EN Chemistry of Materials 2017-08-03

Abstract Black phosphorus (BP) possesses unique physical properties and, owing to its intrinsic instability, the proper surface and chemical coordination is key point in many applications. Herein, a facile efficient lanthanide‐coordination strategy based on lanthanide (Ln) sulfonate complexes designed passivate functionalize different BP‐based nanostructures including quantum dots, nanosheets, microflakes. By means of Ln–P coordination, lone‐pair electrons are occupied, thus preventing...

10.1002/smll.201801405 article EN Small 2018-06-21

Abstract 2D materials with large specific surface area and robust mechanical properties are appropriate for electrocatalysis. However, the unsatisfactory adsorption energy limited active sites restrict their commercial application. Herein, a facile rapid electrochemical strategy enabling synchronous exfoliation doping is designed to directly synthesize metal‐doped from bulk crystals. By using black phosphorus as model, various metal doped phosphorene such BP (Co) , (Mo) (Ni) obtained,...

10.1002/smtd.201900083 article EN Small Methods 2019-04-10

Black phosphorus quantum dots are incorporated into liposomal bilayers to produce a drug delivery system with excellent near-infrared (NIR) photothermal properties and release capability controlled by light.

10.1039/c8cc03423k article EN Chemical Communications 2018-01-01

A two-dimensional (2D) antimicrobial nanoagent is synthesized by incorporating the titanium aminobenzenesulfanato complexes (Ti-SA4) onto black phosphorus nanosheets (BPs). The strong P–Ti coordination between Ti-SA4 and BPs results in high loading capacity (∼43%) of enhances stability against oxidation. Compared to bare Ti-SA4, Ti-SA4@BPs exhibit improved antibacterial efficacy, most bacteria are inactivated within 3 h with a dose only 50 μg/mL. underlying mechanism investigated. This...

10.1021/acsanm.8b02065 article EN ACS Applied Nano Materials 2019-01-30

Abstract The photothermal performance of black phosphorus (BP) in the near infrared (NIR)‐II bio‐window (1000–1500 nm) is low, which limits its biomedical applications. Herein, ultrasmall nickel phosphide quantum dots (Ni 2 P QDs) are synthesized with BP (BPQDs) as template by topochemical transformation. size Ni QDs ≈3.5 nm, similar to that BPQDs, whereas absorption and conversion efficiency at 1064 nm (43.5%) significantly improved compared those BPQDs. To facilitate vivo applications, an...

10.1002/advs.202305762 article EN cc-by Advanced Science 2023-12-19

Flexible pressure sensors with a broad range and high sensitivity are greatly desired yet challenging to build. Herein, we have successfully fabricated pressure–temperature dual sensor via an ionic assisted charge enhancement strategy. Benefiting from the immobilization effect for [EMIM+] [TFSI–] ion pairs transfer between liquid (IL) HFMO (H10Fe3Mo21O51), formed IL-HFMO-TPU shows of 25.35 kPa–1 sensing (∼10 MPa), respectively. Furthermore, device exhibits durability stability (5000 cycles@1...

10.1021/acs.nanolett.4c01506 article EN Nano Letters 2024-05-28

Background and Purpose: Although inorganic nanomaterials have been widely used in multimodal cancer therapies, the intrinsic contributions of materials are not well understood sometimes underestimated.In this work, bioactive phospho-therapy with black phosphorus nanosheets (BPs) for vivo tumor suppression is studied.Methods: Orthotopic liver acute myeloid leukemia chosen as models solid hematological tumor, respectively.BPs injected into mice through tail vein growth monitored by IVIS...

10.7150/thno.43092 article EN cc-by Theranostics 2020-01-01

Abstract The stability and activity of self‐cascade enzymes based on glucose oxidase (GOx) peroxidase (POD) are usually low, which has significant limitations in tumor catalytic therapy. Building nanoislands‐supported single‐atom nanozymes with strong atomic‐nano interaction is an effective strategy for enhancing the enzyme‐like activity. Herein, noble metal iridium (Ir) single‐atoms successfully deposited CeO 2 quantum dots (QDs) nanoislands to construct Ir/CeO (SANIs). QDs abundant oxygen...

10.1002/adfm.202504434 article EN Advanced Functional Materials 2025-03-27

Scalable synthesis of few-layered phosphorene typically relies on liquid ultrasonic/shear exfoliation but this technique suffers from drawbacks such as the long processing time, small sheet size, and poor quality. Herein, a simple efficient plasma-liquid for rapid (∼5 minutes) scalable production high-quality has been described. The plasma-exfoliated tunable thickness less than 10 nanometers large size over micrometer, enabling fabrication macroscopic photodetection device with good...

10.1039/c9cc07640a article EN Chemical Communications 2019-11-15

1. The effect of the voltage-dependent Ca channel (VDCC) antagonist omega-conotoxin-MVIIC (omega-CTx-MVIIC) on presynaptic influx and synaptic transmission was studied in area CA1 guinea pig hippocampus. transient ([Ca]t) field excitatory postsynaptic potential (fEPSP) evoked by a single electrical stimulus were simultaneously recorded at CA3 to synapses. 2. omega-CTx-MVIIC dose dependently blocked fEPSP [Ca]t without affecting fiber volley resting level. During application omega-CTx-MVIIC,...

10.1152/jn.1995.73.5.1965 article EN Journal of Neurophysiology 1995-05-01

Abstract Metal phosphide nanoribbons are suitable building blocks for flexible photoelectronic microdevices due to the special electronic structure, large contact area, and excellent mechanical properties. In this work, single‐crystal copper (Cu 3 P NRs) prepared topochemically from crystalline red phosphorus (cRP retain cRP morphology. The Cu NRs used construct memristors on ITO/PEN substrate with native oxidized shell of serving as charge trapping layer modulate resistance switching...

10.1002/adfm.202110900 article EN Advanced Functional Materials 2021-12-01

Gastric cancer is one of the most common types cancer, with a high mortality rate. The aim this study was to investigate role several key molecules, including cytokeratin (CK) 19 and CK20, urokinase plasminogen activator (uPA), C-reactive protein (CRP) matrix metalloproteinase (MMP)-9, which are involved in invasion metastasis, order determine whether they may be considered as novel prognostic factors for gastric cancer. Peripheral blood collected from 165 patients adenocarcinoma who...

10.3892/mco.2015.624 article EN Molecular and Clinical Oncology 2015-08-18

Open AccessCCS ChemistryRESEARCH ARTICLE1 Jun 2019Black Phosphorus: An Effective Feedstock for the Synthesis of Phosphorus-Based Chemicals Lie Wu†, Shi Bian†, Hao Huang, Jiahong Wang, Danni Liu, Paul K. Chu and Xue-Feng Yu Wu† Center Biomedical Materials Interfaces, Shenzhen Institutes Advanced Technology, Chinese Academy Sciences, 518055 (China) , Bian† Huang Wang Department Physics Science, City University Hong Kong, Kowloon 999077, Kong Liu *Corresponding author: E-mail Address: [email...

10.31635/ccschem.019.20180013 article EN cc-by-nc CCS Chemistry 2019-06-01

In article number 1801405, Xue-Feng Yu and co-workers establish a facile lanthanide-coordination strategy based on lanthanide sulfonate complexes for surface modification of various black phosphorus nanostructures. It presents an efficient method to protect against oxidation, the magnetic resonance or fluorescence derived from enable functionalization extending its application range.

10.1002/smll.201870134 article EN Small 2018-07-01

Optimal approaches to patients with local recurrence of rectal cancer are unclear in China. This study aimed evaluaty -30te the clinical outcomes and toxicity associated different treatment regimens for cancer.A retrospective chart review previous radical surgical between March 2010 December 2017 curative intent was performed. Disease-related endpoints included progression-free survival (PFS) overall (OS) using Kaplan-Meier method. Toxicities were assessed Common Terminology Criteria Adverse...

10.2147/cmar.s278427 article EN cc-by-nc Cancer Management and Research 2020-11-01

The antifogging coating based on super-hydrophilic polymer is regarded as the most promising strategy to avoid fogging but suffers from short-term effectiveness due failure induced by water invasion. In this study, a black phosphorus nanosheets (BPs) hybrid hetero-network (PUA/PAHS/BPs HN) was prepared UV curing for first time achieve long-term performance. (HN) structure composed of two novel cross-linked acrylic resin and polyurethane acrylate. Different physical blending, covalent P-C...

10.3390/nano13010086 article EN cc-by Nanomaterials 2022-12-24
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