A5074866331- Lung Cancer Treatments and Mutations
- Obstructive Sleep Apnea Research
- Cancer Immunotherapy and Biomarkers
- Cancer Treatment and Pharmacology
- Gastric Cancer Management and Outcomes
- Ferroptosis and cancer prognosis
- Colorectal Cancer Treatments and Studies
- Lymphoma Diagnosis and Treatment
- Polyoxometalates: Synthesis and Applications
- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Colorectal and Anal Carcinomas
- Metal-Organic Frameworks: Synthesis and Applications
- Pelvic floor disorders treatments
- Lung Cancer Diagnosis and Treatment
- Helicobacter pylori-related gastroenterology studies
- Colorectal Cancer Surgical Treatments
- Chemical Synthesis and Reactions
- Cancer Genomics and Diagnostics
- Lung Cancer Research Studies
- Epigenetics and DNA Methylation
- Radiomics and Machine Learning in Medical Imaging
- Esophageal Cancer Research and Treatment
- Organ Transplantation Techniques and Outcomes
- Cardiac Imaging and Diagnostics
China University of Geosciences
2025
Southeast University
2025
Second Affiliated Hospital of Nanjing Medical University
2020-2025
Xinxiang Medical University
2023-2024
Xinjiang Medical University
2017-2024
Tumor Hospital of Xinjiang Medical University
2017-2024
Brandeis University
2024
The University of Texas Southwestern Medical Center
2021-2024
Nanjing Medical University
2020-2024
Wuxi People's Hospital
2024
The epoxidation of olefins with H2O2 was performed a tungsten-containing catalyst. This insoluble catalyst forms soluble active species by the action H2O2, and when is used up, precipitates for easy recycling. Thus, advantages both homogeneous heterogeneous catalysts are combined in one system through reaction-controlled phase transfer When coupled 2-ethylanthraquinone/2-ethylanthrahydroquinone redox process production, O2 can be propylene to oxide 85% yield based on...
Engineered glyphosate resistance is the most widely adopted genetically modified trait in agriculture, gaining widespread acceptance by providing a simple robust weed control system. However, extensive and sustained use of as sole mechanism has led to field selection for glyphosate-resistant weeds induced significant population shifts with inherent tolerance glyphosate. Additional mechanisms that can complement crops are, therefore, urgently needed. 2,4-dichlorophenoxyacetic acid (2,4-D) an...
<h3>Objective</h3> Stem cell transplantation provides a promising alternative for the treatment of fulminant hepatic failure (FHF). However, it lacks fundamental understanding stem cells' activities. Our objective was to clarify cell-recipient interactions overcoming barriers clinical application. <h3>Design</h3> We used an in-house large-animal (pig) model FHF rescue by human bone marrow mesenchymal cells (hBMSCs) and profiled The control groups pigs (n=15 per group) both received...
Silicosis is a fatal occupational lung disease which currently has no effective treatment. Dihydroquercetin (DHQ) flavonoid compound known for its anti-inflammatory, anti-oxidant and anti-cancer bioactivity. However, whether DHQ protects against silica-induced fibrosis remains unknown. Therefore, we aimed to investigate the effect of on underlying molecular mechanism in vivo vitro . Our results demonstrated that treatment markedly attenuated SiO 2 -induced inflammation degree tissues C57BL/6...
Helicobacter pylori is an important pathogenic factor in gastric carcinogenesis. Angiogenesis (i.e., the growth of new blood vessels) closely associated with incidence and development cancer. Our previous study found that COX-2 stimulates cancer cells to induce expression angiogenic VEGF through unknown mechanism. Therefore, aim this was clarify role angiogenesis H. pylori-induced development. To relationship between infection angiogenesis, we first investigated colonization, COX-2, VEGF,...
BACKGROUND. HBV-related acute-on-chronic liver failure (HBV-ACLF) is hallmarked by high short-term mortality rates, calling for accurate prognostic biomarkers initial risk stratification.
BACKGROUND:Increasing evidence suggests that cancer-associated inflammation is associated with poorer outcomes. The neutrophil-to-lymphocyte ratio (NLR), considered as a systemic marker, thought to predict prognoses in colorectal cancer. In this study, we explored the association between NLR and following neoadjuvant chemoradiotherapy (CRT) for locally advanced rectal cancer (LARC). MATERIAL AND METHODS:From February 2002 December 2012, group of 202 patients diagnosed LARC receiving CRT...
Renal ischemia-reperfusion (IR) injury is one of the most common acute kidney injuries, but there still a lack effective treatment in clinical setting. Trehalose (Tre), natural disaccharide, has been demonstrated to protect against oxidative stress, inflammation, and apoptosis. However, whether it could IR-induced renal needs be investigated. In an vivo experiment, C57BL/6J mice were pretreated with or without Tre (2 g/kg) through daily single intraperitoneal injection from 3 days before IR...
Daptomycin is effective in treating infections caused by antibiotic-resistant Gram-positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococci (VRE), and S. (VRSA). Due to its distinct mechanism of action toward multidrug-resistant bacteria, daptomycin provides an attractive structural motif generate new daptomycin-based antibiotics combat the problem bacterial resistance. In this study, we used total synthesis method produce analogues...
Integrins are involved in extracellular and intracellular signaling often aberrantly expressed tumors. Integrin beta 2 (ITGB2) has previously been demonstrated to be correlated with the host defense. However, expression profile role of ITGB2 non-small-cell lung cancer (NSCLC) remain unclear. Here, we found that genetic alterations was predominated by gene mutation copy number deletion using cBioPortal analysis, its downregulated NSCLC tissues, as validated UALCAN, TCGA, GEO databases our...
Objective: The goal of this study is to evaluate pulmonary function and respiratory center drive in patients with early-stage idiopathic Parkinson's disease (IPD) facilitate early diagnosis Disease (PD). Methods: 43 IPD (Hoehn Yahr scale 1) 41 matched healthy individuals (e.g. age, sex, height, weight, BMI) were enrolled study. Motor status was evaluated using the Movement Disorders Society-Unified PD Rating Scale (MDS-UPDRS). Pulmonary measured tests (PFT). All also subjected a series...
Since most d-amino acids (DAAs) are utilized by bacterial cells but not mammalian eukaryotic hosts, recently DAA-based molecular imaging strategies have been extensively explored for noninvasively differentiating infections from the host's inflammatory responses. Given glutamine's pivotal role in survival, cell growth, biofilm formation, and even virulence, here we report a new positron emission tomography (PET) approach using d-5-[11C]glutamine (d-[5-11C]-Gln) potential clinical assessment...
To explore the novel diagnostic value of epigenetic imprinting biomarkers in thyroid nodules.A total 550 patients with fine-needle aspiration (FNA)-evaluated and histopathologically confirmed nodules were consecutively recruited from eight medical centers. Quantitative chromogenic imprinted gene situ hybridization (QCIGISH) was used to assess allelic expression genes SNRPN HM13, on basis which a grading model for developed. The retrospectively trained 124 postsurgical samples, optimized 32...
We report on a synthesis protocol, experimental characterization, and theoretical modeling of active pulsatile Belousov–Zhabotinsky (BZ) hydrogels. Our two-step technique allows independent optimization the geometry, chemical, mechanical properties BZ gels. identify role surrounding medium chemistry gel radius for occurrence oscillations, quantified by Damköhler number, which is ratio chemical reaction to diffusion rates. Tuning size maximize its chemomechanical oscillation amplitude, we...
The aim of this study was to evaluate the clinical characteristics and survival outcomes patients with primary mediastinal germ cell tumor (PMGCT) by identifying prognostic factors efficacies different treatment modalities.