A5102798092- Drilling and Well Engineering
- Hydraulic Fracturing and Reservoir Analysis
- Methane Hydrates and Related Phenomena
- Coal Properties and Utilization
- Oil and Gas Production Techniques
- Erosion and Abrasive Machining
- Hydrocarbon exploration and reservoir analysis
- CO2 Sequestration and Geologic Interactions
- Metallurgy and Material Forming
- Spacecraft and Cryogenic Technologies
- Structural Response to Dynamic Loads
- Immune cells in cancer
- Neuroinflammation and Neurodegeneration Mechanisms
- Combustion and Detonation Processes
- Metal Forming Simulation Techniques
- Thyroid Cancer Diagnosis and Treatment
- Transportation Safety and Impact Analysis
- Corrosion Behavior and Inhibition
- Particle Dynamics in Fluid Flows
- High-Velocity Impact and Material Behavior
- Advanced machining processes and optimization
- Industrial Engineering and Technologies
- Tunneling and Rock Mechanics
- Fluid Dynamics and Heat Transfer
- High-Temperature Coating Behaviors
Harbin Medical University
2025
Second Affiliated Hospital of Harbin Medical University
2025
China University of Petroleum, East China
2015-2024
Beijing University of Civil Engineering and Architecture
2022-2024
Neurological Surgery
2023-2024
Northwestern University
2023-2024
Shanghai Tenth People's Hospital
2020-2022
Tongji University
2020-2022
Wuhan Union Hospital
2022
Shandong Agricultural University
2022
Abstract As a key component of the standard care for glioblastoma, radiotherapy induces several immune resistance mechanisms, such as upregulation CD47 and PD-L1. Here, leveraging these radiotherapy-elicited processes, we generate bridging-lipid nanoparticle (B-LNP) that engages tumor-associated myeloid cells (TAMCs) to glioblastoma via anti-CD47/PD-L1 dual ligation. We show engager B-LNPs block PD-L1 promote TAMC phagocytic activity. To enhance subsequent T cell recruitment antitumor...
Background: The risk stratification system of the American College Radiology Thyroid Imaging Reporting and Data System (ACR TI-RADS) for thyroid nodules is affected by low diagnostic specificity. Machine learning (ML) methods can optimize performance in medical image analysis. However, it unknown which ML-based pattern more effective improving reducing nodule biopsies. Therefore, we compared ML-assisted visual approaches radiomics with ACR TI-RADS unnecessary fine-needle aspiration biopsy...
Introduction Glioblastoma multiforme (GBM) pathobiology is characterized by its significant induction of immunosuppression within the tumor microenvironment, predominantly mediated immunosuppressive tumor-associated myeloid cells (TAMCs). Myeloid play a pivotal role in shaping GBM microenvironment and influencing immune responses, with direct interactions effector critically impacting these processes. Methods Our study investigates CXCR6/CXCL16 axis T-cell tissues. We examined surface...
During hydraulic fracturing operations of low-permeability reservoirs, packers are the key component to ensure success multistage fracturing. Packers enable sections wellbore be sealed off and separately fractured by pressure, one at a time, while remainder is not affected. However, reliable sealing properties packer rubber required meet high-pressure high-temperature (HPHT) conditions reservoirs (such as 70 MPa 170 °C). In this study, structures with two different materials optimized...
Field gas explosion experiments were conducted on two types of polyurea coated metal plates (PCMPs). The resistance performance PCMP quantified based failure criteria and relative deformation. mechanism was analyzed from the perspective stress propagation phase transition. results showed that under fluctuating upward load, dynamic response process gradually transitioned quasi elastic-plastic vibration to enhanced plastic structural in both elastic stages conformed overpressure criterion....
To explore the novel diagnostic value of epigenetic imprinting biomarkers in thyroid nodules.A total 550 patients with fine-needle aspiration (FNA)-evaluated and histopathologically confirmed nodules were consecutively recruited from eight medical centers. Quantitative chromogenic imprinted gene situ hybridization (QCIGISH) was used to assess allelic expression genes SNRPN HM13, on basis which a grading model for developed. The retrospectively trained 124 postsurgical samples, optimized 32...
The CO2 corrosion behaviour of X65 carbon steel under water-in-oil droplet and oil-in-water was systematically investigated by a combination scanning electron microscopy, Raman spectroscopy, NPFLex3D COMSOL simulation. Under the droplet, formation crystalline FeCO3 can be contributed to high concentration Fe2+ CO32-, short diffusion path near edge promoted precipitation. islands caused invasion water found, indicating that small droplets emphasised development localized underneath oil droplet.
Five types of polyurea elastomers were synthesized by changing the isocyanate component and mechanical properties materials measured. Fiber-reinforced cement boards (FRCB) strengthened with different formulations processed, a series experiments carried out on specimens gas explosion devices. The results showed that conventional polyureas had their own advantages. Based overpressure criterion, blast resistances reinforced plates quantitatively evaluated, best was selected to guide formulation...
Abstract Casing corrosion during CO 2 injection or storage results in significant economic loss and increased production risks. Therefore, this paper, a corroded casing risk assessment model based on analytic hierarchy process fuzzy comprehensive evaluation is established to identify potential risks time. First, the rate residual strength characteristics are analyzed through tests numerical simulations, respectively, determine factors that may lead an accident. Then, index system for six...