A5017222098- Ocular Surface and Contact Lens
- Nanoplatforms for cancer theranostics
- Advanced Nanomaterials in Catalysis
- Glaucoma and retinal disorders
- Fungal Infections and Studies
- Antifungal resistance and susceptibility
- Antibiotic Use and Resistance
- Corneal Surgery and Treatments
- Pneumocystis jirovecii pneumonia detection and treatment
- Environmental remediation with nanomaterials
- Fibroblast Growth Factor Research
- Antimicrobial Resistance in Staphylococcus
- Mesenchymal stem cell research
- Bacterial Identification and Susceptibility Testing
- Extracellular vesicles in disease
- 2D Materials and Applications
- RNA regulation and disease
- Patient Satisfaction in Healthcare
- Sulfur Compounds in Biology
- Dermatology and Skin Diseases
- Microbial Fuel Cells and Bioremediation
- Advanced Glycation End Products research
- Advanced oxidation water treatment
- Advanced biosensing and bioanalysis techniques
- Nasolacrimal Duct Obstruction Treatments
Shenzhen Institutes of Advanced Technology
2023-2025
Chinese Academy of Sciences
2023-2025
University of Chinese Academy of Sciences
2025
Zhengzhou University of Light Industry
2023-2024
Weifang Medical University
2023
Peking University Shenzhen Hospital
2023
Tianjin Medical University
2019-2021
Tianjin Medical University Eye Hospital
2019-2021
National Taiwan University Hospital
2008-2014
Abstract The photothermal performance of black phosphorus (BP) in the near infrared (NIR)‐II bio‐window (1000–1500 nm) is low, which limits its biomedical applications. Herein, ultrasmall nickel phosphide quantum dots (Ni 2 P QDs) are synthesized with BP (BPQDs) as template by topochemical transformation. size Ni QDs ≈3.5 nm, similar to that BPQDs, whereas absorption and conversion efficiency at 1064 nm (43.5%) significantly improved compared those BPQDs. To facilitate vivo applications, an...
Rationale: Corneal transplantation is an effective treatment to corneal blindness. However, the immune rejection imperils allograft survival. An interventional modality urgently needed inhibit and promote In our previous study, subconjunctival injections of bone marrow-derived mesenchymal stem cells (BM-MSCs) into a rat model extended survival for 2 d. this we sought generate IL-10-overexpressing BM-MSCs, aiming boost survival-promoting effects BM-MSCs on allografts explore molecular...
Abstract The stability and activity of self‐cascade enzymes based on glucose oxidase (GOx) peroxidase (POD) are usually low, which has significant limitations in tumor catalytic therapy. Building nanoislands‐supported single‐atom nanozymes with strong atomic‐nano interaction is an effective strategy for enhancing the enzyme‐like activity. Herein, noble metal iridium (Ir) single‐atoms successfully deposited CeO 2 quantum dots (QDs) nanoislands to construct Ir/CeO (SANIs). QDs abundant oxygen...
Voriconazole, posaconazole, caspofungin, micafungin, and anidulafungin demonstrated potent in vitro activities against 286 invasive Candida isolates. Analysis of the fluconazole susceptibilities 204 bloodstream glabrata isolates revealed a rapid shift from susceptible (64% 1999 to 2001 19% 2007) susceptible-dose dependent (27% 75% 2007).
Purpose . To observe ocular surface changes in Type II diabetic patients with different disease durations and to understand the correlations between clinical parameters durations. Methods In this cross-sectional, prospective study, 51 healthy controls 91 diabetes were enrolled. The diabetics divided into 3 subgroups according duration, including duration <10 y group, 10 20 ≥21 group. All subjects underwent examinations, lipid layer thickness (LLT), blinking rate, tear meniscus height...
Abstract An important mechanism involved in dry eye (DE) is the association between tear hyperosmolarity and inflammation severity. Inflammation DE might be mediated by NLRP3 inflammasome, which activated exposure to reactive oxygen species (ROS). A combination of carboxymethylcellulose (CMC) α-melanocyte stimulating hormone (α-MSH) may influence through this mechanism, thus avoiding defects signal drug. In study, we assessed whether treatment comprising CMC combined with α-MSH could...
To investigate the regulatory roles of members peroxisome proliferator-activated receptor (PPAR) family in lacrimal gland dysfunction under conditions desiccating stress or diabetes.Quantitative polymerase chain reaction (qPCR) was used to examine expression PPARs cornea, conjunctiva, meibomian gland, and adult rats. The rats were divided into 3 groups: a control group, dry eye diabetic group. phenol red threads test, tear film break-up time (BUT) test fluorescein staining carried out...
Objective The immune rejection mediated by CD4+ T cell and antigen presenting macrophages is the leading cause of corneal transplantation failure. Bone marrow-derived mesenchymal stem cells (BM-MSCs) possess robust immunomodulatory potentials, have been shown us others to promote allograft survival. However, immunological mechanism underlying protective effects BM-MSCs remains unclear. Therefore, in current study, this was investigated a BM-MSC-treated rat model rejection, hope facilitate...
This study proposed a new concept of “co-processing” waste activated sludge with low organic content (WAS-LOC) peroxysulfate and environmentally friendly nanoscale zero-valent iron (Fe0). Fe0, peroxysulfate, the combination Fe0(co-processing) were added to different alkaline pretreatment fermentation systems. The results showed that system displayed remarkable hydrolysis performance compared other systems highest production proteins polysaccharides 482.04 224.21 mg chemical oxygen demand...
This study evaluated a “co-processing” waste activated sludge strategy with peroxysulfate and environmentally friendly zero-valent iron nanoparticles (Fe0). Fe0, peroxysulfate, co-processing Fe0 were added to different fermentation systems. The results showed that the system displayed remarkable hydrolysis performance compared other systems, was 108-1.55 times (protein) 1.19-1.67 (polysaccharide) for However, exhibited good acidification which 1.35-41.73times enhanced activity of protease,...
Peroxisome proliferators-activated receptor-γ (PPAR-γ) is a member of the nuclear receptor superfamily. It has ability regulating lipid and glucose metabolization, anti-inflammatory inhibition autoimmunity. PPAR-γ may be effective for treating dry eye through limiting production inflammatory factors lacrimal gland, participating in development aging meibomian inflammation conjunctiva controlling diabetes Sjogren’s syndrome. (Int Rev Ophthalmol, 2018, 42: 371-375) Key words: dry...