A5012035198- Birth, Development, and Health
- Adipose Tissue and Metabolism
- Pregnancy and preeclampsia studies
- Gestational Diabetes Research and Management
- SARS-CoV-2 and COVID-19 Research
- Veterinary Oncology Research
- Genetic and phenotypic traits in livestock
- Metabolism, Diabetes, and Cancer
- Animal Virus Infections Studies
- Diet and metabolism studies
- Adipokines, Inflammation, and Metabolic Diseases
- Rabies epidemiology and control
- Spanish History and Politics
- Memory, violence, and history
- Assisted Reproductive Technology and Twin Pregnancy
- Infectious Encephalopathies and Encephalitis
- Ruminant Nutrition and Digestive Physiology
- Conflict, Peace, and Violence in Colombia
- Child Nutrition and Water Access
- Body Composition Measurement Techniques
- Tendon Structure and Treatment
- Regulation of Appetite and Obesity
- Congenital Anomalies and Fetal Surgery
- Salivary Gland Tumors Diagnosis and Treatment
- Cardiovascular Function and Risk Factors
Universidad Europea
2024
Universidad Alfonso X el Sabio
2018-2021
Universidad Complutense de Madrid
2014-2016
The present study aimed to determine, in a swine model of leptin resistance, the effects type and timing maternal malnutrition on growth patterns, adiposity metabolic features progeny when exposed an obesogenic diet during their juvenile development possible concomitant offspring sex. Thus, four groups were considered. A CONTROL group involved pigs born from sows fed with fulfilling daily maintenance requirements for pregnancy. treated females same but either 160% or 50% pregnancy entire...
Maternal energy restriction during pregnancy predisposes to metabolic alterations in the offspring. The present study was designed evaluate phenotypic and consequences following maternal undernutrition an obese pig model define potential role of hypothalamic gene expression programming effects. Iberian sows were fed a control or 50 % restricted diet for last two-thirds gestation. Newborns assessed body organ weights, hormonal status, genes implicated homeostasis, glucocorticoid function...
The use of polyphenols is a promising strategy for preventing or alleviating intrauterine growth restriction (IUGR) because polyphenol supplementation increases plasma antioxidant capacity and improves oxidative stress at the feto-placental unit; which are recognized as main issues in IUGR. However, there scarcity experimental data on both realistic benefits potential hazards during gestation. Hence, we aimed to swine model IUGR pregnancy determine possible effects maternal with...
Abstract COVID-19 is a zoonotic disease caused by SARS-CoV-2. Infections of animals with SARS-CoV-2 have recently been reported, and an increase severe lung pathologies in domestic dogs has also detected veterinarians Spain. Therefore, further descriptions the pathological processes those that show symptoms similar to described humans affected would be highly valuable. The potential for companion contribute continued transmission community spread this known human-to-human urgent issue...
The present study evaluated the effectiveness of sildenafil citrate (SC) to improve placental and fetal growth in a diet-induced rabbit model intrauterine restriction (IUGR). Pregnant rabbits were fed either ad libitum (Group C) or restricted 50% dietary requirements R) treated with SC SC). treatment improved development by increasing vascularity vessel hypertrophy decidua. assessment feto-placental haemodynamics showed higher resistance pulsatility indices at middle cerebral artery (MCA)...
Intrauterine growth restriction (IUGR) is associated with adverse perinatal outcomes and late-onset diseases in offspring. Eating disorders, voluntary caloric maternal undernutrition can all induce IUGR but a relevant model required to measure its possible consequences. In this work, pregnant rabbits were used as an model. Control females ( n= 4) received ad libitum diet throughout pregnancy, whereas underfed 5) restricted 50% of their daily requirements. Offspring size was measured by...
New Findings What is the central question of this study? effect prepuberal metformin therapy and lifestyle in an obese swine model (Iberian gilts) with thrifty genotype on patterns growth, fattening, metabolic status attainment puberty? main finding its importance? An obesogenic diet had deleterious effects corpulence, adiposity parameters. These features were favourably modulated by adequate treatment, which favoured muscle deposition. However, advanced onset puberty, would be a negative...
The main role of early nutritional programming in the current rise obesity and associated diseases is well known. However, translational studies are mostly based postnatal food excess and, thus, there a paucity information on phenotype individuals with prenatal deficiencies but adequate conditions. Thus, we assessed effects (comparing descendants from females fed diet fulfilling 100 or only 50% their requirements for pregnancy) gene expression, patterns growth fattening, metabolic status...
Abstract Background The objective of this study was to investigate the metabolic and osmotic effects different doses glycerol or a – propylene glycol mixture in Sarda sheep with aim identify those able beneficially modify ewe’s status without harmful changes red blood cell (RBC) indices. Thereafter, selected were tested for their on ovarian activity during an induced follicular phase compared hormonal treatment equine chorionic gonadotrophin (eCG). Results Glycerol administered alone (G...
Chemodectomas are low prevalence tumors with complex clinical management. Many present as an incidental finding however, in other dogs, they produce pericardial effusion and/or compression, leading to the appearance of severe signs. There currently several approaches: surgery, radiotherapy, stent placement and chemotherapy. This is first description percutaneous echo-guided radiofrequency ablation aortic body tumors. minimally invasive treatment based on high frequency alternating electrical...
Abstract The present study used a sheep model of intrauterine growth restriction, combining maternal undernutrition and twinning, to determine possible markers early damage the fetal kidney. occurrence deviations in hemodynamics which may be indicative changes blood perfusion was assessed by Doppler ultrasonography. A total 24 divided two groups were fed with same standard grain-based diet but fulfilling either their daily maintenance requirements for pregnancy (control group; n =12, six...
The present study assessed the relationship between obesity induced by lifestyle and systemic oxidative stress possible modulations oral metformin treatments in young individuals, using a translational swine model of associated cardiometabolic disorders (Iberian pig). results indicate existence an age-related increase both adiposity (using hydrogen peroxide as marker), which is higher individuals with obesogenic increased weight obesity. Such effect was not found treated metformin....
Nasal carcinomas in dogs are locally invasive neoplasms with a low metastatic rate that pose significant treatment challenges due to their location and aggressiveness. This study evaluates the safety, feasibility, therapeutic outcomes of computed tomography-guided radiofrequency ablation (CT-guided RFA) 15 diagnosed nasal adenocarcinoma. All patients underwent staging histopathological diagnosis before treatment. CT-guided RFA achieved tumor volume reduction (82.8%) improvement clinical...
Early diagnosis of tendon injuries and accurate long-term monitoring the healing process are key for equine veterinarians that use conventional ultrasonography. The development strain elastography could improve management clinical cases. aim study was to assess intraobserver repeatability interobserver reproducibility manual measurements colored areas tendons within elastograms standardize this modality by comparing analysis images with ImageJ. Twenty injured superficial digital flexor...
Summary COVID-19 is a zoonotic disease originated by SARS-CoV-2. Infection of animals with SARS-CoV-2 are being reported during last months, and also an increase severe lung pathologies in domestic dogs has been detected veterinarians Spain. Therefore it necessary to describe the pathological processes those that show symptoms similar described humans affected COVID-19. The potential for companion contributing continued human-to-human disease, infectivity, community spread urgent issue be...
Background: COVID-19 is a zoonotic disease originated by SARS-CoV-2. Infection of animals with SARS-CoV-2 are being reported during last months, and also an increase severe lung pathologies in domestic dogs has been detected veterinarians Spain. Therefore it necessary to describe the pathological processes those that show symptoms similar described humans affected COVID-19. The potential for companion contributing continued human-to-human disease, infectivity, community spread urgent issue...