- Reproductive Physiology in Livestock
- Antibiotics Pharmacokinetics and Efficacy
- Reproductive Biology and Fertility
- Genetic and phenotypic traits in livestock
- Birth, Development, and Health
- Regulation of Appetite and Obesity
- Inflammatory mediators and NSAID effects
- Ovarian function and disorders
- Veterinary medicine and infectious diseases
- Veterinary Pharmacology and Anesthesia
- Aquaculture disease management and microbiota
- Effects and risks of endocrine disrupting chemicals
- Gestational Diabetes Research and Management
- Animal Behavior and Welfare Studies
- Adipokines, Inflammation, and Metabolic Diseases
- Receptor Mechanisms and Signaling
- Drug Transport and Resistance Mechanisms
- Pregnancy and preeclampsia studies
- Biochemical Analysis and Sensing Techniques
- Fatty Acid Research and Health
- Ichthyology and Marine Biology
- Venomous Animal Envenomation and Studies
- Pain Mechanisms and Treatments
- Marine Sponges and Natural Products
- Veterinary Equine Medical Research
Universidad Complutense de Madrid
2009-2025
Austral University of Chile
2008
Hospital Universitario Puerta de Hierro Majadahonda
2006
National University of the Littoral
1998
Fungal diseases, despite their low incidence in sharks and rays, are considered emerging diseases this group of animals can lead to high mortality rates treatment. The information available related the treatment fungal elasmobranchs is limited frequently based on empirical knowledge provided by professionals clinicians working with these species. use azole antifungal drugs, especially voriconazole, has shown promise as a potential option for infections elasmobranchs, favorable outcomes some...
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Meloxicam is a nonsteroidal anti-inflammatory drug commonly used in avian species. In this study, the pharmacokinetic parameters for meloxicam were determined following single intravenous (i.v.), intramuscular (i.m.) and oral (p.o.) administrations of (1 mg/kg·b.w.) adult African grey parrots (Psittacus erithacus; n = 6). Serial plasma samples collected concentrations using validated high-performance liquid chromatography assay. A noncompartmental analysis was performed. No undesirable side...
The use of polyphenols is a promising strategy for preventing or alleviating intrauterine growth restriction (IUGR) because polyphenol supplementation increases plasma antioxidant capacity and improves oxidative stress at the feto-placental unit; which are recognized as main issues in IUGR. However, there scarcity experimental data on both realistic benefits potential hazards during gestation. Hence, we aimed to swine model IUGR pregnancy determine possible effects maternal with...
This study determined the effects of short-term energy inputs on ghrelin secretion and possible links with changes in follicle population or ovulation rate. Oestrous cycle was synchronized 16 Manchega sheep using progestagen sponges cloprostenol. Half animals were treated from days 0 to 4 by oral administration, twice daily, 200 ml a glucogenic mixture containing 70% glycerol, 20% 1,2-propanediol 10% water; control group received water. The mean (± s.e.m. ) plasma glucose increased...
The present study compared the occurrence of oestrus behaviour and ovulation in response to insertion CIDR devices plus a classical treatment with equine chorionic gonadotrophin (eCG; single dose at removal) or alternative treatments gonadotrophin-releasing hormone (GnRH, either 56 hr after removal, one another removal). appearance during reproductive season ranged between 84% 95% all females showing signs had subsequent ovulations. response, seasonal anoestrus, was similar group treated...
Contents The aims of this study were to evaluate the chronology periovulatory events (oestrus behaviour, LH surge and ovulation) in 16 superovulated Manchega sheep determine whether follicular status at start FSH supply might affect their occurrence. Mean timing for onset oestrus behaviour was detected 28.1 ± 0.7 h after sponge withdrawal; preovulatory ovulation started 37.2 65.4 progestagen withdrawal, respectively. intervals between oestrus, affected by a high individual variability, which...
Abstract OBJECTIVE To determine the pharmacokinetics of meloxicam in African grey parrots ( Psittacus erithacus ) during administration multiple doses. ANIMALS 6 healthy parrots. PROCEDURES Meloxicam was administered at each 3 dosages (1 mg/kg, IM, q 24 h, for 7 days; 1 PO, 12 and 1.6 days) with an 8-week washout period between treatments. Blood samples were collected hours after drug (times presumptive peak trough concentrations) pharmacokinetic analysis. Birds visually assessed all...
Contents The Iberian pig is an autochthonous breed of the Mediterranean area, reared extensively in central and southern areas Spain Portugal that known worldwide for production ham. characteristics ham are related to its abundance intramuscular fat, owing high capacity accumulate fat under skin between muscular fibres. This ability store excess enables survival during periods scarcity it has been found other antique animal breeds even humans, being named as thrifty genotype . reproductive...
Maternal supplementation with hydroxytyrosol, a polyphenol present in olive leaves and fruits, is highly promising strategy to improve the oxidative metabolic status of fetuses at risk intrauterine growth restriction, which may diminish appearance low-birth-weight neonates. The study aimed determine whether by preventing lipid peroxidation, influence fat accretion energy homeostasis liver, as well fatty acid composition liver muscle. results indicate that hydroxytyrosol treatment...
Metformin is an anti-hyperglycemic drug widely used for the treatment of insulin resistance and glucose intolerance currently considered preventing large-for-gestational-age (LGA) offspring in pregnant women affected by obesity or diabetes. Our hypothesis was opposite—metformin may be improving development intrauterine growth restriction (IUGR) appearance small-for-gestational-age (SGA) neonates non-obese non-diabetic but malnourished pregnancies. The current study, performed a swine...
Currently, there is an intense effort to find alternative hormone eCG induce ovulation after estrus synchronization treatments in sheep. One of the proposed alternatives based on use hCG, but results are controversial since fertility rates commonly affected. The present study aims evaluate, therefore, adequacy hCG protocols for and ovulation. Ovarian follicle dynamics, occurrence behavior subsequent ovulation, quality corpora lutea, pregnancy rate controlled natural mating were assessed two...
The study reports on differences in the dynamics of growth and functionality preovulatory follicles response to oestrous synchronization, either by administration two doses prostaglandin or an intravaginal progestagen sponge, goats. progestagen-treated group (n = 8) showed more size (> =5.5 mm) than cloprostenol during follicular phase (4.5 +/- 0.6 vs 1.9 0.2, p < 0.01). diameters largest (LF1, LF2 LF3) were also larger 7.8 0.3 7.0 0.2 mm, 0.05; LF2, 6.7 5.6 0.01; LF3, 5.5 4.2 that 27.2%...
Maternal supplementation with the polyphenol hydroxytyrosol in a swine model of intrauterine growth restriction (IUGR) improves fetal oxidative status, decreases appearance low birth-weight neonates and favors during early postnatal stages (lactation). The current study aimed to determine whether can also improve developmental patterns, metabolic traits, body composition offspring later (from weaning adulthood). A total 21 piglets born from control untreated sows 20 treated last two-thirds...
Maternal supplementation with antioxidants and n3 PUFAs may be a promising strategy to reduce the risk of intrauterine growth restriction preterm delivery, which diminish appearance low-birth-weight neonates. The present study aimed determine benefits risks dietary combining hydroxytyrosol, polyphenol from olive leaves fruits, PUFAs, linseed oil, on developmental patterns metabolic traits offspring in swine, model IUGR pregnancies. results obtained indicate that maternal hydroxytyrosol n-3...
Introduction Fungal diseases are frequently associated with elevated mortality rates in elasmobranchs. Currently, there is a notable absence of scientifically validated therapeutic medications that can ensure both effectiveness and safety when administered to this group animals. The empirical prescription azole antifungal agents, particularly voriconazole, has been posited as potentially efficacious treatment approach for addressing most common mycoses sharks rays. However, still no...
The foreseen shortage of eCG for estrus synchronization in sheep makes necessary the development alternative protocols. aim present work was to evaluate reproductive response breeding season administration GnRH using propylene-glycol as a cosolvent and subcutaneous route slowing extending release GnRH, well most adequate timing such administration. In study, protocols based on short-term CIDR treatment single dose at 36 h after removal induced similar ovarian or intramuscular distilled water...