A5045648319- Diamond and Carbon-based Materials Research
- CAR-T cell therapy research
- Cancer Immunotherapy and Biomarkers
- Lubricants and Their Additives
- Tribology and Wear Analysis
- Metal and Thin Film Mechanics
- Immune Cell Function and Interaction
- Online Learning and Analytics
- Prenatal Screening and Diagnostics
- Thermal properties of materials
- Intelligent Tutoring Systems and Adaptive Learning
- Teaching and Learning Programming
- Advanced materials and composites
- SARS-CoV-2 and COVID-19 Research
- Viral Infectious Diseases and Gene Expression in Insects
- Educational Technology and Assessment
- Solar-Powered Water Purification Methods
- Graphene research and applications
- Renal and related cancers
- Nanowire Synthesis and Applications
- Pediatric Urology and Nephrology Studies
- COVID-19 Clinical Research Studies
- Thermal Expansion and Ionic Conductivity
- Imbalanced Data Classification Techniques
- Single-cell and spatial transcriptomics
Ningbo Institute of Industrial Technology
2022-2025
Chinese Academy of Sciences
2022-2025
Guangzhou Medical University
2023-2024
University of Waterloo
2023-2024
BGI Group (China)
2020-2023
University of Chinese Academy of Sciences
2020-2023
Zhongkai University of Agriculture and Engineering
2022-2023
General Hospital of Shenyang Military Region
2007
The tribological properties of the epoxy were significantly improved due to synergy biomimetic F-CDs and sulfonated h-BN.
Hydraulic technology has been instrumental in the extensive application of offshore mechanical equipment, particularly drilling platforms and ships, where high-performance hydraulic fluids are essential for safe efficient operations. Addressing urgent need water-based as an alternative to traditional oil-based fluids, this study introduces a novel fluid fortified with phytic acid, derived from plant seeds, achieve low biotoxicity, coefficient friction, reduced frictional heat generation. The...
For effective heat dissipation in portable electronics, there is a great demand for lightweight and flexible films with superior thermal transport properties. Despite extensive efforts, enhancing the intrinsic low conductivity of polymers while simultaneously maintaining their flexibility difficult to achieve due dilemma quarrying appropriate filler loading. Herein, cellulose nanofiber-based film high in-plane up 72.53 W m-1 K-1 was obtained by harnessing advantage functionalized boron...
Smart responsive materials are capable of responding to external stimuli and, compared traditional materials, can be effectively reused and reduce usage costs in applications. However, smart often face challenges such as the inability repair extensive damage, instability long-term performance, inapplicability extreme environments. This study combines 2D diamond nanosheets with organic fluorinated molecules prepare a nanofluid (fluorinated nanosheets, F-DN) self-healing self-adhesion...
The preexistence of immune cells in the tumor microenvironment substantiates efficacy immunotherapy cancer patients. Although complex intratumoral heterogeneity has been extensively studied single cell resolution, hi-res spatial investigations are limited. In this study, we performed a transcriptome analysis 4 colorectal adenocarcinoma specimens and 2 paired distant normal to identify molecular pattern involved discontinuous inflammatory response pathologically annotated regions. Based on...
Due to their excellent biocompatibility, outstanding mechanical properties, high strength-to-weight ratio, and good corrosion resistance, titanium (Ti) alloys are extensively used as implant materials in artificial joints. However, Ti suffer from poor wear resulting a considerably short lifetime. In this study, we demonstrate that the chemical self-assembly of novel two-dimensional (2D) diamond nanosheet coatings on combined with natural silk fibroin lubricating fluid synergistically results...
A simple method was proposed to produce a flexible heat spreader with efficient thermal transportation performance.
Dry friction between seal faces, caused by unstable or extreme operating conditions, significantly affects the running stability and service life of mechanical seals. Therefore, in this work, nanocrystalline diamond (NCD) coatings were prepared on surface silicon carbide (SiC) rings hot filament chemical vapor deposition (HFCVD). The test results under dry environment reveals that coefficient (COF) SiC-NCD pairs is about 0.07-0.09, which reduced 83-86% compared to SiC-SiC pairs. wear rate...
Exploiting novel strategies for simultaneously harvesting ubiquitous, renewable, and easily accessible solar energy based on the photothermal effect, efficiently storing acquired thermal plays a vital role in revolutionizing current fossil fuel-dominating structure. Developing black phosphorene-based phase-change composites with optimized conversion efficiencyand high latent heat is most promising way to achieve efficient rapid storage. However, exfoliating high-quality phosphorene...
Solar Energy Harvesting In article number 2303933, Wenying Zhou, Zhongwei Wang, Nan Jiang, Jinhong Yu, and co-workers synthesize high-quality black phosphorus (BP) nanosheets under low-temperature, oxygen-free conditions using a controlled "top-down" method. By adjusting the temperature during ice crystal growth, they achieve well-ordered BP skeletons. The addition of polyethylene glycol results in unprecedented thermal conductivity, excellent performance heat storage, photothermal...
Tumor-specific antigens can activate T cell-based antitumor immune responses and are ideal targets for cancer immunotherapy. However, their identification is still challenging. Although mass spectrometry directly identify human leukocyte antigen (HLA) binding peptides in tumor cells, it focuses on tumor-specific derived from annotated protein-coding regions constituting only 1.5% of the genome. We developed a novel proteogenomic integration strategy to expand breadth epitopes all genomic...
Diamond films prepared by chemical vapor deposition will exhibit different surface morphologies, which are determined the texture and structural perfection of deposited diamond. In general, its morphology can be controlled adjusting conditions. present work, <110> textured diamond film was on single crystalline silicon through pre-seeding nanosheets, rather than controlling The employed nano-sheets were cleavage along a plane, exhibiting good crystallinity. Before deposition,...
T-cell receptor (TCR)-engineered T cells can precisely recognize a broad repertoire of targets derived from both intracellular and surface proteins tumor cells. TCR-T adoptive cell therapy has shown safety promising efficacy in solid immunotherapy. However, antigen-specific functional TCR screening is time-consuming expensive, which limits its application clinically. Here, we developed novel integrated antigen–TCR platform based on droplet microfluidic technology, enabling high-throughput...
Instructors often grant students extensions or grace days to relax deadline constraints. However, researchers have yet investigate the value of time in identifying students' abilities and why use them computing education. Our study shows that scheduling conflicts underestimation coursework were top two reasons late, providing very first qualitative analysis results. By categorizing who used did not cost-free extensions, we found had a significantly lower assignment exam grades than those...
The switchable chimeric antigen receptors (CARs) have shown many advantages in CAR T-cell therapy. However, human primary T-cells are required to evaluate antigen-specific adaptors by IFN-γ assay or FACS analysis, which limits the throughput of adaptor screening. A sensitive and robust CD16-CAR Jurkat NFAT-eGFP reporter system has been developed assess therapeutic efficacy antibody-targeted CAR-T-cell effectively evaluating activation various tumor cells impact immune checkpoint inhibitor...
TCR-T cell therapy plays a critical role in the treatment of malignant cancers. However, it is unclear how cells are affected by PD-L1 molecule tumor environment. We performed an in-depth evaluation on differential expressions can affect functionality T cells.
In programming courses, test-based automated feedback systems often face a limitation: instructors cannot effectively enhance during ongoing assignments. While passing test case may adequately indicate that certain rubric criteria have been met by student's program, failure can arise from many reasons. When fails due to reasons not previously coded for, it create confusion. This tends divert focus genuine learning towards guessing the test. A more effective approach would be for system...