A5101435060- Neural dynamics and brain function
- Neuroscience and Music Perception
- EEG and Brain-Computer Interfaces
- Multisensory perception and integration
- Visual perception and processing mechanisms
- Functional Brain Connectivity Studies
- Neuroscience and Neural Engineering
- Bone health and osteoporosis research
- Bone health and treatments
- Neuroscience and Neuropharmacology Research
- Olfactory and Sensory Function Studies
- Advanced Memory and Neural Computing
- Hearing Loss and Rehabilitation
- stochastic dynamics and bifurcation
- Neural Networks and Applications
- Parathyroid Disorders and Treatments
- Neural Networks and Reservoir Computing
- Tactile and Sensory Interactions
- Neurobiology and Insect Physiology Research
- Bone Metabolism and Diseases
- Memory and Neural Mechanisms
- Color perception and design
- Face Recognition and Perception
- Thyroid Cancer Diagnosis and Treatment
- Bone and Joint Diseases
New York University
2014-2023
Nathan Kline Institute for Psychiatric Research
2014-2023
NYU Langone Health
2022-2023
Semmelweis University
2004-2022
Columbia University
2007-2014
Hungarian Academy of Sciences
1986-2010
Lymphatic Education & Research Network
2010
Pázmány Péter Catholic University
2008
Long Island Jewish Medical Center
2008
Whereas gamma-band neuronal oscillations clearly appear integral to visual attention, the role of lower-frequency is still being debated. Mounting evidence indicates that a key functional property these rhythmic shifting excitability in local ensembles. Here, we show when attended stimuli are stream, delta-band primary cortex entrain rhythm resulting increased response gain for task-relevant events and decreased reaction times. Because hierarchical cross-frequency coupling, delta phase also...
EEG oscillations are hypothesized to reflect cyclical variations in the neuronal excitability, with particular frequency bands reflecting differing spatial scales of brain operation. However, despite decades clinical and scientific investigation, there is no unifying theory organization, role ongoing activity sensory processing remains controversial. This study analyzed laminar profiles synaptic [current source density CSD] multiunit (MUA), both spontaneous stimulus-driven, primary auditory...
The more we anticipate a response to predictable stimulus, the faster react. This empirical observation has been confirmed and quantified by many investigators suggesting that processing of behaviorally relevant stimuli is facilitated probability-based confidence anticipation. However, exact neural mechanisms underlying this phenomenon are largely unknown. Here show performance changes related different levels expectancy originate in dynamic modulation delta oscillation phase. Our results...
Previous studies raise the hypothesis that attentional bias in phase of neocortical excitability fluctuations (oscillations) represents a fundamental mechanism for tuning brain to temporal dynamics task-relevant event patterns. To evaluate this hypothesis, we recorded intracranial electrocortical activity human epilepsy patients while they performed an audiovisual stream selection task. Consistent with our (1) modulation oscillatory entrainment operates distinct network areas including...
ABSTRACT While bisphosphonates reduce fracture risk over 3 to 5 years, the optimal duration of treatment is uncertain. In a randomized extension study (E1) Health Outcomes and Reduced Incidence with Zoledronic Acid Once Yearly−Pivotal Fracture Trial (HORIZON−PFT), zoledronic acid (ZOL) mg annually for 6 years showed maintenance bone mineral density (BMD), decrease in morphometric vertebral fractures, modest reduction turnover markers (BTMs) compared discontinuation after years. To...
The functional significance of the α rhythm is widely debated. It has been proposed that reflects sensory inhibition and/or a temporal sampling or “parsing” mechanism. There also continuing disagreement over more fundamental questions which cortical layers generate rhythms and whether generation equivalent across systems. To address these latter questions, we analyzed laminar profiles local field potentials (LFPs) concomitant multiunit activity (MUA) from macaque V1, S1, A1 during both...
Primates actively examine the visual world by rapidly shifting gaze (fixation) over elements in a scene. Despite this fact, we typically study vision presenting stimuli with held constant. To better understand dynamics of natural vision, examined how onset fixation affects ongoing neuronal activity absence stimulation. We used multiunit and current source density measurements to index firing patterns underlying synaptic processes macaque V1. Initial averaging neural synchronized suggested...
Abstract The caudal medial auditory area (CM) has anatomical and physiological features consistent with its role as a first‐stage (or “belt”) association cortex. It is also site of multisensory convergence, robust somatosensory responses. In this study, we investigated the cerebral cortical sources inputs to CM by injecting retrograde tracers in macaque monkeys. A companion paper describes thalamic connections (Hackett et al., J. Comp. Neurol. [this issue]). likely input were adjacent...
We measured the timing, areal distribution, and laminar profile of fast, wavelength-insensitive slower, wavelength-sensitive responses in V1 extrastriate areas, using current-source density analysis awake macaque monkeys. There were 3 main findings. 1) confirmed previously reported significant ventral–dorsal stream latency lags at level V4 (V4 mean = 38.7 ms vs. middle temporal 26.9 ms) inferotemporal cortex (IT 43.4 dorsal bank superior sulcus 33.9 ms). 2) found that inputs areas V1, V4, IT...
Studies in humans and monkeys report widespread multisensory interactions at or near primary visual auditory areas of neocortex. The range scale these effects has prompted increased interest interconnectivity between the putatively "unisensory" cortices lower hierarchical levels. Recent anatomical tract-tracing studies have revealed direct projections from cortex to area (V1) secondary (V2) that could serve as a substrate for influences over low-level processing. To better understand...
Recent neuroscience advances suggest that when interacting with our environment, along previous experience, we use contextual cues and regularities to form predictions guide perceptions actions. The goal of such active "predictive sensing" is selectively enhance the processing representation behaviorally relevant information in an efficient manner. Since a hallmark schizophrenia impaired selection, tested whether this deficiency stems from dysfunctional predictive sensing by measuring degree...