A5100392566- Adsorption and biosorption for pollutant removal
- Drug Solubulity and Delivery Systems
- Pharmacological Effects of Natural Compounds
- Advanced Drug Delivery Systems
- Mesenchymal stem cell research
- Dermatology and Skin Diseases
- MRI in cancer diagnosis
- Analytical Methods in Pharmaceuticals
- Natural product bioactivities and synthesis
- Circadian rhythm and melatonin
- Hereditary Neurological Disorders
- Arsenic contamination and mitigation
- Peripheral Nerve Disorders
- Immunotherapy and Immune Responses
- Musicians’ Health and Performance
- Tissue Engineering and Regenerative Medicine
- Wastewater Treatment and Nitrogen Removal
- Vestibular and auditory disorders
- Environmental remediation with nanomaterials
- Phytochemistry and Bioactive Compounds
- Retinal Imaging and Analysis
- Electrokinetic Soil Remediation Techniques
- Advancements in Transdermal Drug Delivery
- Apelin-related biomedical research
- Biofuel production and bioconversion
Korea Institute of Industrial Technology
2023
Korea Environmental Industry and Technology Institute
2018
Kyung Hee University
2012-2017
Eulji University Hospital
2016
East Carolina University
2016
Dankook University
2014-2015
Sungkyunkwan University
2015
Samsung Medical Center
2015
Gyeongsang National University
2015
Dankook University Hospital
2014
Gastroretentive (GR) systems are designed to prolong gastric residence time allow sustained absorption and improve the oral bioavailability of drugs with a narrow window in upper part gastrointestinal tract. The present study aimed develop GR system for acyclovir using 3D printing technology evaluate its vivo pharmacokinetics after administration Beagle dogs. consisted gastro-floating device, which can float fluid, prepared by fused deposition modeling printer conventional sustained-release...
It has been studied that mesenchymal stem cells (MSCs) have the capability to promote angiogenesis. Furthermore, there is strong evidence hypoxic conditions can enhance angiogenesis and immune modulation mediated by MSCs, a notion applied in many fields of clinical application. In present study, we compared efficacy hypoxia preconditioned human umbilical cord-derived (hUC-MSCs) normoxia conditioned hUC-MSCs for treatment ischemic injury hindlimbs an immunodeficient mouse model. Expression...
Background: Monitoring of an animal's blood glucose concentration is critical for diagnostic and therapeutic decisions. Over the past few decades, portable meters (PBGMs) have been used to monitor concentrations in animals. Recently, new improved PBGMs made available on market.Objective: The purpose this study was evaluate four use dogs cats.Animals methods: A total 155 venous samples 85 cats were tested using PBGMs. Control solutions from manufacturers determine precision each meter....
Salicornia europaea (Amaranthaceae) (SE) has been shown to reduce obesity, but it remains a problem as food supplement because of its high salt content (25-35% NaCl).This study investigated the anti-obesity effects and mechanism action desalted SE powder (DSP).Sprague-Dawley rats (n = 50) were divided into normal control group (NC), high-fat diet (HFD)-induced obesity (HFD), HFD groups co-administered DSP (250 500 mg/kg) or Garcinia cambogia (Clusiaceae) extract (GE, 200 mg/kg, standard...
The contamination of water by arsenic (As) is a serious environmental problem, and many cost effective adsorbents have been developed to solve this problem. This study examines the effectiveness reusing alum sludge from purification facilities as As in aqueous systems. Adsorption kinetics adsorption isotherm temperature were methods investigated. Kinetics revealed that As(III) As(V) has rate-limiting steps such surface diffusion pore diffusion. In equilibrium study, Langmuir was well fitted...
Atopic dermatitis (AD) is an inflammatory skin disorder that both uncomfortable and distressing to patients, its prevalence has been steadily increasing. It obvious the identification of efficient markers AD in plasma would offer possibility effective diagnosis, prevention, treatment strategies. In this study, a proteomic approach was used analyze glycoproteins from children with healthy child donors. Several protein spots showing significant quantitative changes patients were identified....
The removal characteristics of Cd(II), Cu(II), Pb(II), and Zn(II) from model aqueous solutions by 5 natural Mongolian zeolites were investigated. adsorption metals on reached a plateau value within 6 h. kinetic data fitted with models. equilibrium capacity the was measured using Langmuir Freundlich isotherm order zeolite Pb(II) > Cu(II) Cd(II). maximum depends its cation exchange pH. leaching properties simulated four solutions. results show that can be used as an adsorbent for metal ions or...
The aim of this study was to investigate the chondroprotective effect a standardized extract (KBH-JP-040) Korean traditional herbs Kalopanax pictus Castor-Aralia, Hericium erinaceus (Bull.) Persoon, and Astragalus membranaceus Schischkin on in vivo vitro osteoarthritis (OA) models. Cultured rat chondrocytes were pre-treated with KBH-JP-040 (50, 100 200 μg/mL) for 1 h, then recombinant human IL-1α (rhIL-1α) 24 h. For model, rabbits (n = 60) equally divided into experimental groups: normal...
Paenibacillus elgii SD17 (KCTC <TEX>$10016BP^T$</TEX>=NBRC <TEX>$100335^T$</TEX>) was recently reported as a new species. Based on its inhibitory activity to Thanatephorus cucumeris AG1-1, strain further evaluated for potential biocontrol agent against soil-borne diseases of turf grasses in Korea. P. showed broad spectrum antimicrobial vitro test and suppressed development grass diseases; Pythium blight caused by aphanidermatum brown patch T. AG1-1 creeping bentgrass (Agrostis palustris) the...
Reverse osmosis (RO) has been widely utilized in water reclamation plants and produces a concentrated brine (or reject) stream as by-product. RO concentrates (ROC) contain vast quantities of salts dissolved organic matter, such biomass humic-like substances, which hinder biological wastewater treatment (such nitrogen removal). In this study, we cultivated granular sludge an aerobic sequencing batch reactor to treat municipal with loading rate 2.1–4.3 kgCOD/m3 day at room temperature (25 °C),...
We developed a simple, sensitive, and effective ultra-performance liquid chromatography/tandem mass spectrometry (HPLC-MS/MS) method with an electrospray ionization (ESI) interface in multiple reaction monitoring (MRM) positive ion modes to determine diazepam concentrations human plasma using voriconazole as internal standard (IS). Diazepam IS were detected at transition 285.2→193.1 350.2→127.1, respectively. After liquid-liquid extraction (LLE) 1.2 ml of ethyl acetate:n-hexane (80:20, v/v),...
A bronchial artery (BA) aneurysm is a rare, life-threatening disease when it ruptures.Recently, we experienced case of massive hemoptysis due to BA rupture in pulmonary tuberculosis cavity, treated with embolization followed by surgical resection the cavitary lesion.To our knowledge, this first associated tuberculosis.(
세포 노쇠화(cell senescence)는 나이 듦에 따른 내인성 노화 및 질병들에서 나타날 수 있는 세포의 노화인자 발현, 세포분열 정지 등의 현상으로 일컬어진다. 피부세포의 경우, 외부요인으로 인한 노쇠화가 일어나 세포분열의 기능 이상이 관찰되며 이는 피부노화를 가속화시키는 요인이 된다. 본 연구에서는, cordycepin을 이용하여 노화된 노쇠화 억제 향상을 유도하여 피부노화 개선의 가능성을 제시하였다. 사람에서 유래한 섬유아세포를 <TEX>${\beta}$</TEX>-galactosidase 활성 세포염색 결과, 많은 계대의 세포에서 발현이 높게 나타남을 알 있었다. 항산화 항염 효과가 알려진 세포에 처리하였을 때 활성이 확연히 떨어짐을 확인하였고 무혈청 배지 조건에서 계대 증식 생존율을 높이는 결과를 보였으며 노쇠화와 연관성이 대두되고 미토콘드리아의 기능관련 실험을 진행한 높은 ROS억제능이 나타났다. 연구를 통하여 사람 피부 섬유아세포에서의 cordycepin의...